[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"kyphosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:kyphosis":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,64,92,108,130,160,187,211],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":36,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":63},"100523273","studying-melatonin-and-recovery-in-teens-100523273",false,"NCT06093477","Studying Melatonin and Recovery in Teens","SurgerySMART: Studying Melatonin and Recovery in Teens","SurgerySMART","Inclusion Criteria:\n\nPatients\u002Fyouth:\n\n* Age 12-18 years\n* Participants undergoing elective major musculoskeletal surgery for eligible conditions\n* California state resident\n* Regular access to internet and smartphone\n* Can read and understand English or Spanish\n\nParents\u002Fcaregivers\n\n* Biological parent or legal guardian of youth\n* Can read and understand English or Spanish\n\nExclusion Criteria:\n\nPatients\u002Fyouth\n\n* Prescription medication for premorbid insomnia\n* Cognitive impairment or developmental delay\n* Does not agree to a 1-week washout if taking over the counter supplements or other sleep aids prior to the start of the study medication\n* High risk for sleep related breathing disorder\n* Chronic medical condition that is severe\u002Fsystemic or requires regular treatment regimen\n* Psychiatric admission in prior 30 days\n* Patients that underwent major surgery in the last 3 months, or those that have not fully recovered from a prior surgery\n* BMI ≥ 99th percentile\n* Enrollment in another therapeutic study\n* Any serious underlying medical or psychiatric condition, that, in the opinion of the investigator, would contraindicate the patient's participation in the study","ALL","12 Years","18 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep. Melatonin is available as a dietary supplement that may be effective in promoting longer, higher quality sleep. This study will assess the feasibility and acceptability of melatonin for teens undergoing major musculoskeletal surgery, as well as determine optimal measured outcomes (sleep, pain, health-related quality of life) at short- and long-term follow-up.",[28,29,30,31,32,33,34,35],"Juvenile; Scoliosis","Scoliosis Idiopathic","Scoliosis; Adolescence","Scoliosis;Congenital","Kyphosis","Spondylolisthesis","Pectus Surgery","Hip Surgery",[37,38,39,40,41,42,43,44,45,46,47,48,49,50],"sleep","pain medicine","pediatric pain medicine","melatonin","pilot feasibility trial","acute pain","chronic pain","CPSP","chronic postsurgical pain","spinal fusion surgery","adolescent","perioperative melatonin","hip surgery","pectus surgery","RECRUITING","2026-03-16",{"date":54,"type":55},"2026-03-18","ACTUAL",{"date":57,"type":55},"2024-05-30",{"date":59,"type":22},"2028-03-31",{"name":61,"class":62},"Stanford University","OTHER",1,{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":4,"enrollmentInfo":72,"targetDuration":4,"studyType":74,"phases":4,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":91},"100430451","prospective-evaluation-of-complex-adult-spinal-deformity-cad-treated-with-minimally-invasive-surgery-100430451","NCT04885244","Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery","Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery (MIS)","MIS","Inclusion Criteria:\n\n1. \\>18 years of age at the time of treatment\n2. Diagnosis of adult congenital, degenerative, idiopathic, neuromuscular, inflammatory or iatrogenic spinal deformity\n3. EOS full body or standing 36\" AP \\& Lateral images of entire spine\n4. Surgery to be schedule to take place within 6 months (otherwise PROMs\u002FRadiographic images to be recollected)\n\n   AND Either:\n5. One of the following Radiographic criteria:\n\n   1. PI-LL ≥ 25 degrees\n   2. Thoracolumbar\u002Flumbar scoliosis ≥ 20 degrees\n   3. SVA \\>10cm\n   4. PT \\> 30 OR\n6. One of the Following Procedural criteria:\n\n   1. Surgery to include \\> 3 levels percutaneous posterior spinal instrumentation or 3 level stand-alone interbody. (Levels = vertebra (i.e. percutaneous screws at L2, L3, L4 would be eligible for posterior instrumentation and\u002For L3-L4, L4-L5 would be eligible as stand-alone for interbodies)\n   2. Posterior UIV and LIV must be placed percutaneously\n   3. Single-position surgery ≥ 3 levels fused (Levels=vertebra; S1 is counted as a level; S2 \\&\u002For pelvis\u002Filium is not)\n   4. Staged ≥ 3 levels fused with percutaneous pedicle screws\n   5. 3 column osteotomy with percutaneous fixation\n   6. ACR incorporating open or percutaneous fixation as long as UIV and LIV are percutaneous screws\n\nExclusion Criteria:\n\n1. Deformity due to acute trauma\n2. Active spine tumor or infection\n3. Patient is unwilling or unable to complete questionnaires\n4. Women who are pregnant\n5. Prisoners\n6. Open Posterior spinal fusion is planned (Open Anterior, i.e. ALIF, is acceptable)",{"count":73,"type":22},500,"OBSERVATIONAL","Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.",[77,78,32,79],"Adult Spinal Deformity","Scoliosis","Sagittal Imbalance",[78,32,79,81],"Spinal Deformity","2026-02-12",{"date":84,"type":55},"2026-02-17",{"date":86,"type":55},"2021-07-28",{"date":88,"type":22},"2034-12-31",{"name":90,"class":62},"International Spine Study Group Foundation",12,{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":4,"enrollmentInfo":98,"targetDuration":4,"studyType":74,"phases":4,"briefSummary":96,"conditions":100,"keywords":101,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":102,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":106,"locationsCount":107},"100430670","prospective-multicenter-case-control-analysis-of-the-versatie-posterior-fixation-system-to-prevent-proximal-junctional-failure-in-long-posterior-spinal-fusion-constructs-for-adult-patients-100430670","NCT04888104","Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients","Inclusion Criteria:\n\n1. \\>18 years of age at the time of treatment\n2. EOS full body or standing 36\" AP \\& Lateral images of entire spine\n3. Posterior spine fusion with pedicle screw fixation construct of 5 or more levels\n4. Pedicle screw fixation to be supplemented proximally with NuVasive VersaTie system\n5. Upper instrumented vertebra (UIV) terminating at a newly instrumented level\n6. Lowest instrumented vertebra (LIV) sacrum\u002Fpelvis\n7. Surgery scheduled to take place in the next 6 months\n\nExclusion Criteria:\n\n1. Active spine tumor or infection\n2. Deformity due to acute trauma\n3. Prisoners\n4. Women who are pregnant\n5. Patient is unwilling or unable to complete questionnaires",{"count":99,"type":22},225,[77,78,32],[78,32,79],{"date":84,"type":55},{"date":104,"type":55},"2021-07-09",{"date":88,"type":22},{"name":90,"class":62},9,{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":4,"enrollmentInfo":116,"targetDuration":118,"studyType":74,"phases":4,"briefSummary":119,"conditions":120,"keywords":121,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":123,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},"100377408","complex-adult-deformity-surgery-cads-100377408","NCT04194138","Complex Adult Deformity Surgery (CADS)","Multi-Center Prospective Evaluation of Complex Adult Spinal Deformity Surgery","CADS","Criteria:\n\nInclusion Criteria:\n\n1. Diagnosis of adult congenital, degenerative, idiopathic or iatrogenic spinal deformity\n2. Full body EOS radiographic assessment (sagittal and coronal visualization from skull to foot)\n3. Complex patients are defined as and meeting any one of the subsequent criteria:\n\n   1. Radiographic criteria:\n\n      * PI-LL ≥ 25 degrees\n      * TPA ≥ 30 degrees\n      * SVA\\>15cm\n      * Thoracic scoliosis ≥ 70 degrees\n      * Thoracolumbar\u002Flumbar scoliosis ≥ 50 degrees\n      * Global coronal malalignment \\>7cm\n   2. Procedural criteria:\n\n      * Posterior spinal fusion \\> 12 levels\n      * 3 column osteotomy or ACR\n   3. Geriatric criteria:\n\n      * Age \\>65 years and minimum 7 levels of spinal instrumentation during surgery\n\nExclusion Criteria:\n\n1. Age \\\u003C18 years of age\n2. Active spine tumor or infection\n3. Deformity due to acute trauma\n4. Neuromuscular conditions\u002Fdiseases (Parkinson's, Multiple Sclerosis, Post-polio syndrome)\n5. Syndromic scoliosis\n6. Inflammatory arthritis\u002Fauto immune diseases (Rheumatoid arthritis, Lupus, Ankylosing Spondylitis)\n7. Prisoners\n8. Women who are pregnant\n9. Non English speaking patients",{"count":117,"type":22},1500,"10 Years","Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.",[77,78,32,79],[78,32,79,122],"Spinal deformity",{"date":84,"type":55},{"date":125,"type":55},"2018-07-30",{"date":127,"type":22},"2032-07-31",{"name":90,"class":62},18,{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":136,"targetDuration":4,"studyType":23,"phases":138,"briefSummary":139,"conditions":140,"keywords":145,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":63},"100613036","the-effect-of-three-dimensional-exercises--schroth-method--on-trunk-muscle-endurance-sleep-quality-and-quality-of-life-in-adolescents-with-hyperkyphosis-100613036","NCT07261358","The Effect of Three-Dimensional Exercises ( Schroth Method ) on Trunk Muscle Endurance, Sleep Quality, and Quality of Life in Adolescents With Hyperkyphosis","Inclusion Criteria:\n\n* Adolescents between 12 and 18 years of age\n* Presence of thoracic kyphosis with a T3-T12 Cobb angle ≥45° measured on a lateral thoracic radiograph\n* Sufficient physical and cognitive ability to actively participate in the exercise protocol for at least 3 months\n* Adequate communication and cognitive capacity to understand the educational materials provided\n* Ability and willingness to regularly complete the exercise log throughout the study period\n\nExclusion Criteria:\n\n* Scoliosis with a Cobb angle \\>10° in the coronal plane\n* Presence of structural spinal deformities such as vertebral fracture, spondylolisthesis\n* History of previous spinal surgery\n* Neuromuscular disorders that may affect the spine (e.g., cerebral palsy, muscular dystrophy)\n* Structural or functional pathologies involving the spine, pelvic complex, or shoulder girdle\n* Balance disorders such as vestibular dysfunction, vertigo, or other conditions affecting postural control\n* Inability to comply with the exercise protocol due to intellectual disability, severe behavioral disorders, or significant communication impairments\n* Participation in professional-level sports activities that may influence exercise capacity or musculoskeletal function\n* Presence of serious cardiopulmonary diseases (e.g., congenital heart disease, pulmonary hypertension)",{"count":137,"type":22},60,[25],"Adolescence is a critical period for spinal growth, and progression of thoracic hyperkyphosis may lead to pain, weak trunk muscles, sleep disturbances, and reduced quality of life. This study aims to investigate the effects of three-dimensional exercise program based on the Schroth Method on trunk muscle endurance, thoracic kyphosis angle, pain, sleep quality and quality of life in adolescents aged 12-18 years with hyperkyphosis.",[141,32,142,143,144],"Spine Deformity","Adolescent","Sleep Quality","Trunk Muscle Endurance",[146,147,148,149],"postural kyphosis","sleep quality","trunk muscle endurance","adolescent spine deformity","2026-02-08",{"date":152,"type":55},"2026-02-11",{"date":154,"type":55},"2025-10-06",{"date":156,"type":22},"2026-05-01",{"name":158,"class":159},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":168,"enrollmentInfo":169,"targetDuration":4,"studyType":23,"phases":171,"briefSummary":172,"conditions":173,"keywords":174,"overallStatus":178,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":183,"leadSponsor":185,"locationsCount":63},"100612608","dns-vs-thoracic-stabilization-exercises-in-thoracic-kyphosis-100612608","NCT07255794","DNS vs Thoracic Stabilization Exercises in Thoracic Kyphosis","Comparison of the Effects of Dynamic Neuromuscular Stabilization and Thoracic Stabilization Exercises on Thoracic Erector Spinae Muscle Strength Using EMG Biofeedback in Individuals With Kyphosis","TK-DNS-TS","Inclusion Criteria:\n\n* Age between 18 and 40 years.\n* Presence of thoracic kyphosis based on clinical and flexible ruler assessment.\n* Able to perform exercise-based interventions.\n* Voluntarily agrees to participate and signs the informed consent form.\n* No neurological, systemic, cardiac or orthopedic condition that would prevent safe participation in the exercise program.\n\nExclusion Criteria:\n\n* Age outside the range of 18-40 years.\n* Pregnancy.\n* Malignancy.\n* History of spinal surgery within the last year.\n* Currently performing spinal or intensive core stabilization exercises.\n* Visual, auditory or cognitive impairment that would interfere with cooperation during the intervention.\n* Contraindications to exercise participation.\n* Non-adherence to the exercise program (not performing exercises for three consecutive days).","40 Years",{"count":170,"type":22},30,[25],"This randomized controlled trial aims to compare the effects of Dynamic Neuromuscular Stabilization (DNS) exercises and thoracic stabilization exercises on thoracic erector spinae muscle strength, thoracic kyphosis angle, pain and trunk stabilization in individuals with thoracic kyphosis. Thirty participants aged 18-40 years with thoracic kyphosis will be randomly allocated to a DNS exercise group or a thoracic stabilization exercise group. Surface EMG biofeedback will be used to assess thoracic erector spinae muscle activation, while pain, thoracic kyphosis angle and trunk endurance will be evaluated using validated clinical tests. The interventions will be applied for 6 weeks, and outcomes will be assessed before and after the intervention period.",[32],[175,176,177],"dynamic neuromuscular stabilization(DNS)","electromyography","thoracic stabilization exercises","NOT_YET_RECRUITING","2025-11-20",{"date":181,"type":55},"2025-12-01",{"date":181,"type":22},{"date":184,"type":22},"2026-02-15",{"name":186,"class":62},"Esra BECENI",{"id":188,"slug":189,"hasResults":11,"nctId":190,"briefTitle":191,"officialTitle":192,"acronym":4,"eligibilityCriteria":193,"healthyVolunteers":11,"sex":17,"minAge":194,"maxAge":195,"enrollmentInfo":196,"targetDuration":4,"studyType":23,"phases":198,"briefSummary":199,"conditions":200,"keywords":201,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":202,"lastUpdatePostDateStruct":203,"startDateStruct":205,"completionDateStruct":207,"leadSponsor":209,"locationsCount":63},"100582722","comparison-of-exercise-with--without-bracing-in-office-workers-with-kyphosis-100582722","NCT06867003","Comparison of Exercise With & Without Bracing in Office Workers With Kyphosis","Effectiveness of Physical Therapy With &Amp; Without Bracing on Posture, Pain and Functional Outcomes in Office Workers With Kyphosis","Inclusion Criteria:\n\n* Office workers diagnosed with Postural Kyphosis\n* age limit 30 to 45years\n* Experience of upper back or neck pain lasting at least three months\n* Spend a minimum of 6 hours per day in a seated position for work.\n\nExclusion Criteria:\n\n* History of spinal surgery, severe scoliosis, or other significant spinal deformities.\n\nCurrent engagement in any structured physical therapy program or use of bracing for posture. Any neurological or musculoskeletal disorders impacting posture or movement.","30 Years","45 Years",{"count":197,"type":22},36,[25],"The study aims to Compare PT and bracing in improving posture, pain, and functionality in patient with kyphosis.\n\nIt also assess the additive benefits of combining PT with bracing. It also identify sustainable, non-surgical approaches for managing kyphosis in office",[32],[32],"2025-07-03",{"date":204,"type":55},"2025-07-09",{"date":206,"type":55},"2025-02-20",{"date":208,"type":22},"2026-02-20",{"name":210,"class":62},"Riphah International University",{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":11,"sex":17,"minAge":218,"maxAge":4,"enrollmentInfo":219,"targetDuration":4,"studyType":23,"phases":221,"briefSummary":222,"conditions":223,"keywords":224,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":233,"completionDateStruct":235,"leadSponsor":237,"locationsCount":63},"100522447","managing-kyphosis-with-exercise-100522447","NCT06082739","Managing Kyphosis With Exercise","Effectiveness of Various Exercises in Managing Kyphosis","Inclusion Criteria:\n\n* Patients ages 8 and older with postural or Scheuermann's kyphosis with \\>45° of kyphosis or \\>10° of thoracolumbar kyphosis from T11-L1 or other cases which seem to have excessive kyphosis.\n* Parents of patients aged 17 and younger who are 18 and older and cognitively able to complete a survey will be included in the study as well.\n\nExclusion Criteria:\n\n* Patients with congenital kyphosis or scoliosis greater than 30°.\n* Parents of patients aged 17 and younger who are less than 18 years of age or cognitively unable to complete a survey will be excluded from the study.\n* Any records flagged \"break the glass\" or \"research opt out.\"","8 Years",{"count":220,"type":22},120,[25],"The primary objective of this study is to determine if stretching exercises as a conservative treatment option will correct kyphosis in postural and Scheuermann's kyphosis.",[32],[225,226,227,228,229],"Scheuermann's","thoracolumbar","postural","stretching","back","2025-01-15",{"date":232,"type":55},"2025-01-17",{"date":234,"type":55},"2023-11-06",{"date":236,"type":22},"2029-10",{"name":238,"class":62},"Cedars-Sinai Medical Center"]