[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"labor-augmentation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:labor-augmentation":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100560717","phase-4-calcium-carbonate-to-augment-labor-contractions-100560717",false,"NCT06580782","Calcium Carbonate to Augment Labor Contractions","CALC","Inclusion Criteria:\n\n* 18 years or older\n* Nulliparas (no prior pregnancy lasting 20 weeks or greater of gestation)\n* Gestational age above 36 weeks, at enrollment\n* Present for induction or augmentation of labor inclusive of medical indication, elective induction at greater than 39 weeks' gestation, trial of labor after cesarean\n* Singleton gestation (a multiple gestation reduced to a singleton, either spontaneously or therapeutically, before 14 0\u002F7 weeks of gestation is acceptable)\n* Ability to give informed consent\n* Planned to undergo initiation of oxytocin infusion by their maternity care provider\n\nExclusion Criteria:\n\n* Unable to understand or read English\n* Presence of tachysystole (defined as more than 5 contractions in 10 minutes averaged over 30 minutes), recurrent variable or late fetal decelerations, and bradycardia in the prior 30 minutes before enrollment\n* Non-vertex presenting fetus at enrollment\n* Planned for cesarean delivery or contraindication to labor by institutional policy (e.g., placenta previa, vasa previa, active genital herpes infection, previous transmural myomectomy)\n* Multi-fetal gestation (twins, triplets, and higher order multiples)\n* Known contraindication to taking calcium carbonate including renal calculus, high urine calcium levels, elevated serum calcium, low serum phosphate, achlorhydria, or suspected digoxin toxicity.\n* Deliveries with fetal chronic and\u002For pregnancy-related conditions, IUFD (Intra Uterine Fetal Death) or premature \\< 36 weeks of gestation.\n* Major fetal anomaly suspected prenatally (defined as a fetal anomaly with anticipated neonatal intensive care unit admission)\n* Suspected alloimmunization (given the increased likelihood for anticipated neonatal intensive care unit admission)\n* Known severe fetal growth restriction (estimated fetal weight \\<3rd percentile) or abnormal umbilical artery Doppler studies (given the increased likelihood for anticipated neonatal intensive care unit admission)\n* Participation in another interventional study that influences management of labor and delivery or perinatal morbidity or mortality\n* Known allergic reactions to synthetic oxytocin intravenous solution or to Calcium Carbonate\n* Significantly impaired consciousness or executive function (e.g., intubated or sedated)\n* Patients treated with calcium channel blockers such as nifedipine or magnesium.\n* Chronic renal failure and hyperphosphatemia.\n* Inability to tolerate oral intake (i.e., nausea\u002Fvomiting)",true,"FEMALE","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The investigators think that calcium carbonate can act as an assistive medication to improve contractions during labor.",[27,28,29],"Labor Dystocia","Labor Induction","Labor Augmentation",[31,32,29,33,34],"Labor","Pregnancy","Calcium Carbonate","labor induction","RECRUITING","2025-10-21",{"date":38,"type":39},"2025-10-23","ACTUAL",{"date":41,"type":39},"2024-11-18",{"date":43,"type":21},"2025-12",{"name":45,"class":46},"Weill Medical College of Cornell University","OTHER"]