[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"labor\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:labor":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100506348","phase-4-impact-of-prophylactic-ephedrine-on-fetal-heart-tracing-and-uterine-tetanic-contraction-after-cse-100506348",false,"NCT05873218","Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE","Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After Combined Spinal Epidural on Laboring Parturients","Inclusion Criteria:\n\n* Women aged 18-55 years\n* Requesting labor analgesia\n* Able to provide informed written consent\n* Category 1 fetal tracing prior to placement of neuraxial anesthesia\n\nExclusion Criteria:\n\n* Refusal of neuraxial anesthesia\n* History of hypertension\n* Suspected pre-eclampsia\n* Category 2 or 3 fetal tracing prior to placement of neuraxial anesthesia",true,"FEMALE","18 Years","55 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","Labor analgesia is an important component of the care of laboring patients. A known side effect of combined spinal and epidural anesthesia (a type of labor analgesia) is an increased incidence of category II fetal heart rate tracing (defined below) and low blood pressure. The study team aims to study if a prophylactic dose of ephedrine will decrease the occurrence of this type of tracing after combined spinal epidural (CSE) anesthesia placement. Ephedrine is not currently routinely used as prevention for category II tracings or low blood pressure. The use of Ephedrine in this study is investigational (this is the first time that the drug has been studied for its effect on these conditions).\n\nFetal heart rate (FHR) tracings are classified into three categories. In clinical practice, FHR tracing categories are used as a guide to obstetric management and suggest the following approach:\n\n* Category I tracing is \"reactive\" and reassuring → may continue labor\n* Category II tracing is neither category I nor category III. For obvious reasons, category II is the broadest and largest category, consisting of various FHR tracing patterns that do not fit into either category I or category III.\n* Category III tracing is non-reassuring → expedited vaginal or cesarean delivery recommended.\n\nA Category II tracing is not diagnostic. Most pregnancies have at least one Category II tracing. There is not always an identifiable reason for a Category II tracing.\n\nEphedrine is a medication that causes an increase in heart rate and blood pressure while also causing some degree of relaxation of the uterus therefore improving uterine blood flow. It has been used in the obstetric population for over 50 years without issues. The dose that the research team will administer, 7.5 mg, is below the dose the research team will often administer to treat hypotension (low blood pressure).",[28],"Labor",[30,31,32,33,34],"Randomized Control Trial","Prophylactic Ephedrine","Fetal Heart Rate Tracing","Combined Spinal Epidural","Labor analgesia","RECRUITING","2026-05-04",{"date":38,"type":39},"2026-05-06","ACTUAL",{"date":41,"type":39},"2023-06-26",{"date":43,"type":22},"2027-05",{"name":45,"class":46},"Icahn School of Medicine at Mount Sinai","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100621839","the-effect-of-chocolate-consumption-during-labor-on-second-stage-duration-100621839","NCT07375836","The Effect of Chocolate Consumption During Labor on Second Stage Duration","Inclusion Criteria:\n\n1. Gestational age ≥37 weeks\n2. Single fetus in cephalic presentation\n3. Spontaneous or induced labor in the active phase (dilation ≥ 5 cm).\n4. Normal assessment of the mother and fetus upon admission to the delivery room (normal indices, normal monitoring and biophysical profile)\n5. BMI 18-35 -\n\nExclusion Criteria:\n\n1. Multiple pregnancies\n2. Gestational age \\\u003C37 weeks\n3. Gestational or pre-gestational diabetes\n4. Significant underlying diseases\n5. Previous cesarean section\u002Fmyomectomy\n6. Known significant fetal malformation\n7. Sensitivity to chocolate ingredients\n8. Lack of documentation of necessary information -","50 Years",{"count":56,"type":22},180,[58],"NA","Childbirth is an energy-intensive physiological process, requiring sustained effort comparable in intensity to moderate physical activity. Studies suggest that providing an available energy source during labor, such as dextrose infusion or natural carbohydrate-rich foods such as dates, may shorten the duration of labor and improve cervical dilation without adversely affecting obstetric outcomes. The primary objective of the study is to examine whether giving chocolate during labor affects the duration of the second stage of labor, compared to a control group that will not receive a nutritional intervention. The study is a prospective, randomized, controlled trial that will be conducted in the delivery room of Hillel Yaffe Medical Center. Healthy pregnant women with a singleton pregnancy at ≥37 weeks gestational age, in spontaneous or induced labor, without diabetes (pre\u002Fgestational), will be recruited to participate. Participants in the intervention group will receive one serving of 50 grams of milk chocolate (cocoa content 25-30%, without filling or additives) at a cervical dilation of 6 cm or more (and not yet fully dilated). The mother will be asked to consume the serving gradually over 30 minutes. Milk chocolate was chosen because it is better tolerated compared to dark chocolate, has a more gentle profile of active ingredients (which can increase nausea and heartburn) and provides a source of available carbohydrates. The study will be conducted in accordance with the guidelines of the Ministry of Health's procedure for medical experiments on humans, and will be conducted after approval by the Institutional Helsinki Committee.",[28,61,62],"Second Stage of Labor","Pregnancy",[64,65,66,67,62,28,68],"Second stage of labor","Oral carbohydrate intake","Non-pharmacologic intervention","Maternal exhaustion","Randomized controlled trial","NOT_YET_RECRUITING","2026-02-01",{"date":72,"type":39},"2026-02-04",{"date":74,"type":22},"2026-02",{"date":76,"type":22},"2027-01",{"name":78,"class":79},"Hillel Yaffe Medical Center","OTHER_GOV",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":16,"sex":17,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100554462","the-effect-of-pregnant-controlled-sacral-massage-on-mothers-labor-pain-perception-process-and-midwives-satisfaction-100554462","NCT06499402","The Effect of Pregnant-controlled Sacral Massage on Mothers' Labor Pain, Perception, Process and Midwives' Satisfaction","Inclusion Criteria:\n\n* Participating in the study voluntarily\n* having a cervical dilatation of 5-6 cm,\n* being between 38-40 weeks of pregnancy,- being a single fetus, having a cephalic presentation,\n* having a fetal weight between 2.5-4 kg,\n* having no vision-hearing problems,\n* having communication and cooperation skills\n\nExclusion Criteria:\n\n* having pregnancy complications\n* Those who have acute inflammatory problems in soft tissues, skin or joints, burns, nerve injuries, open wounds, rheumatoid and gouty arthritis,\n* those who have used any non-pharmacological methods will not be admitted.","18 Days","45 Days",{"count":89,"type":22},112,[58],"Our study aims to determine the effect of pregnant-controlled automatic sacral massage on mothers' labor pain, perception, process and midwives' satisfaction. The research was planned as a randomized controlled experimental study. A total of 112 women, 56 pregnant women in the experimental and control groups, will be included in the study. In this project, an automatic massage device will be used during the active phase (when the cervical opening is between 5-6 cm and 10 cm) and a massage device in line with the pregnancy-controlled sacral massage application protocol. Pregnant women are followed throughout the active phase of labor and indicators reflecting labor pain, progress of labor, and the health status of the mother and the baby are used with the \"Individual Identification Form\", \"Visual Comparison Scale\", \"Labor Monitoring Form\", \"Mother's Birth Perception Scale (ADAS)\". The satisfaction of midwives will be evaluated with the \"Evaluation of Satisfaction Status of Midwives Form\".",[93,28],"Labor Pain","2024-07-11",{"date":96,"type":39},"2024-07-15",{"date":98,"type":22},"2024-07-22",{"date":100,"type":22},"2024-09-22",{"name":102,"class":46},"Osmaniye Korkut Ata University"]