[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lactic-acid\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lactic-acid":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100545635","the-impact-of-rhinoplasty-approach-and-used-autologous-cartilage-grafts-on-the-nasal-skin-soft-tissue-envelope-metabolism-100545635",false,"NCT06384469","The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism","Inclusion Criteria:\n\n* Adult patients undergoing primary functional rhinoplasty who comply with the study\n* Adult patients undergoing primary functional rhinoplasty who have singed the informed consent, previously approved by the ethics commitee.\n\nExclusion Criteria: -\n\n* patients with previous surgical procedures to the nose\n* patients with greater previous injury or burns to the nasal skin\n* patients with autoimmune skin conditions\n* patients with significant cardiovascular diseases\n* patients unwilling to comply with the study\n* patients who do not want to sign the informed consent, previously approved by the ethics commitee.",true,"ALL","18 Years","80 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","This is a prospective observation cohort investigation. Patients, that is participants, undergoing primary functional rhinoplasty will be evaluated in terms of measuring capillary blood lactic acid concentration in the nasal skin-soft tissue envelope immediately after the procedure and 7 days after the procedure.\n\nThe aim of our study is to test whether or not different rhinoplasty approaches and volume of the used autologous cartilage grafts impact the nasal skin-soft tissue metabolism.",[25,26,27,28],"Rhinoplasty","Nasal Skin-soft Tissue Envelope Metabolism","Lactic Acid","Autologous Cartilage Grafting",[30,31,32,33,34,35],"Open rhinoplasty approach","Closed rhinoplasty approach","Lactic acid","Skin-soft tissue envelope","Metabolism","Autologous cartilage grafting","NOT_YET_RECRUITING","2024-04-25",{"date":39,"type":40},"2024-04-29","ACTUAL",{"date":42,"type":21},"2025-01-02",{"date":44,"type":21},"2026-09-01",{"name":46,"class":47},"University Hospital Sestre Milosrdnice","OTHER"]