[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"language-development\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:language-development":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,51,86,108,138,164,192,224,253,281,302],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100528138","using-neuroimaging-and-behavioral-assessments-to-understand-late-talking-100528138",false,"NCT06156865","Using Neuroimaging and Behavioral Assessments to Understand Late Talking","Neuroimaging Reveals Treatment-related Changes in DLD: A Randomized Controlled Trial (Supplement)","Inclusion Criteria:\n\n* child and parent are monolingual\u002Fnative (primarily) English speakers\n* child is enrolled at one of the participating facilities\n* child is recruited via word of mouth, including social media\n* child is between 18 and 30 months of age\n* child does not have any contraindications to magnetic resonance imaging (i.e., intracranial metal implants, claustrophobia)\n* child does not have any uncorrected vision challenges\n\nExclusion Criteria:\n\n* Child does not meet criteria for LT or typical development\n* Standard magnetic resonance imaging exclusion criteria\n* Gestational age less than 37 weeks or greater than 42 weeks\n* Special education placement of child based on ability or behavior",true,"ALL","18 Months","30 Months",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder. While effective and early interventions can mitigate the impact of late talking, not enough is known about its neural basis, yet is needed to inform the design of more individualized interventions. This proposed effort uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie learning and late talking, while also considering their association to treatment-related changes in LT.",[28,29,30],"Developmental Language Disorder","Language Delay","Language Development",[32,33,34,35,36,37],"children","late talking","typical development","assessment","intervention","neuroimaging","RECRUITING","2026-05-29",{"date":41,"type":42},"2026-06-02","ACTUAL",{"date":44,"type":42},"2024-01-19",{"date":46,"type":22},"2027-06-30",{"name":48,"class":49},"University of Toronto","OTHER",2,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":16,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":85},"100607480","saga-for-toddlers-supporting-childrens-linguistic-and-socio-emotional-development-in-early-childhood-education-and-care-100607480","NCT07189104","SAGA for Toddlers. Supporting Children's Linguistic and Socio-Emotional Development in Early Childhood Education and Care","SAGA-T","Inclusion Criteria:\n\n* 11 to 36 -months old at the start of the study\n* Living in Finland\n* Attending Swedish speaking early childhood education and care\n\nExclusion Criteria:\n\n* None","11 Months","36 Months",{"count":61,"type":22},120,[25],"The goal of this study is to investigate whether a shared reading intervention including emotion and mind-related dialogues (SAGA for Toddlers) supports the development of 11 to 36 moth-old-children in early childhood education and care.\n\nThe main questions it aims to answer are:\n\n1. Does the SAGA model support children's social-emotional development?\n2. Does the SAGA model support children's language development?\n\nThe participating children will attend the intervention at the early childhood education and care.\n\nThe participating personnel at the early childhood education and care will receive training, implement the intervention, and answer questionnaires.\n\nThe participating caregivers will attend caregiver-evenings and answers questionnaires.",[65,30],"Social Emotional Competence",[67,68,36,69,70,71,72,73,74,75],"social-emotional development","language development","toddlers","early childhood education and care","caregivers","mentalization theory","SAGA model","group intervention","shared reading intervention","2026-05-04",{"date":78,"type":42},"2026-05-08",{"date":80,"type":42},"2025-09-25",{"date":82,"type":22},"2027-04",{"name":84,"class":49},"University of Helsinki",1,{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":16,"sex":17,"minAge":93,"maxAge":19,"enrollmentInfo":94,"targetDuration":4,"studyType":23,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":85},"100431997","can-the-language-environment-analysis-start-program-improve-childrens-readiness-for-school-lena-program-evaluation-100431997","NCT04905381","Can the Language Environment Analysis Start Program Improve Children's Readiness for School? LENA Program Evaluation","Can a Scalable Parenting Program Improve Children's Readiness for School? An Evaluation of the LENA Start Program","Inclusion Criteria:\n\nEligible adult participants include parents who meet all the criteria listed below.\n\n1. Must be 18 years old or older.\n2. Must have a child between 16 and 30 months old as of September 1, 2022.\n3. Must speak English or Spanish as their native language.\n4. Must live in the catchment area of Alief Independent School District. Children of the adult participants enrolled in the study are eligible to participate. The children must meet all the criteria below.\n\n1\\. Must be between 16 and 30 months old as of September 1, 2022 2. Must speak English or Spanish as their native language. 3. Must live in the catchment area of Alief Independent School District.\n\nExclusion Criteria:\n\nAdult participants will not be eligible for this study if they:\n\n* Are NOT 18 years old or older.\n* Do NOT have a child between 16 and 30 months as of September 1, 2022.\n* Do NOT speak English or Spanish as their native language.\n* Do NOT live in the catchment area of Alief Independent School District.\n\nChildren will not be eligible for this study if they:\n\n* Are NOT between 16 and 30 months as of September 1, 2022.\n* Do NOT speak English or Spanish as their native language.\n* Do NOT live in the catchment area of Alief Independent School District.","16 Months",{"count":95,"type":22},600,[25],"The objective of the project is to implement the LENA Start Program at the Alief The objective of the project is to implement the LENA Start Program at the Alief Independent School District in Houston, Texas. The purpose of the study is to learn how maternal expectations about language development influence the child's language development. Also, the study will evaluate how much the mothers believe can affect their child's language development. More specifically, the program implementation will serve as a model that other school districts can readily replicate.",[30],"2026-04-21",{"date":101,"type":42},"2026-04-24",{"date":103,"type":42},"2022-08-01",{"date":105,"type":22},"2028-12-31",{"name":107,"class":49},"William Marsh Rice University",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":115,"maxAge":4,"enrollmentInfo":116,"targetDuration":4,"studyType":23,"phases":118,"briefSummary":119,"conditions":120,"keywords":124,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":85},"100633641","prevent-language-delays-and-disorders-among-children-of-caregivers-with-substance-use-disorders-with-community-groups-and-individualized-services-100633641","NCT07529327","Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community Groups and Individualized Services","Evidence-based Intervention Enhancements to Reduce Language Delays and Disorders Among Children of Parents With Substance Use Disorders","Inclusion Criteria:\n\n1. Have a:\n\n   1. Self-reported lifetime history of substance use disorder treatment and\u002For\n   2. active substance use in the past year\n2. Be providing care for\u002Fparenting a child at least 10% of the time who is:\n\n   1. between the ages of 12-42 months\n   2. English\u002FSpanish bilingual or monolingual in English or Spanish\n   3. exposed to a third language once a week or less\n   4. not yet combining three or more words regularly\n   5. has less than 150 words in their expressive vocabulary\n3. Be able to provide consent for their target child to participate, or have a legal guardian provide consent for the child to participate\n4. Be able to speak and understand English and\u002For Spanish\n5. Be willing to attend groups once a week for six weeks at a participating site\u002Fgroup time\n6. If assigned additional services, willing to attend Zoom meetings\n7. Be 18 years of age or older\n\nExclusion Criteria:\n\n-Only one caregiver per focal child can participate in the research study. Caregivers whose participating child already has another caregiver enrolled in the research study will not be eligible to participate.","18 Years",{"count":117,"type":22},244,[25],"The goal of this clinical trial is to test ways to improve early language development among young children of parents with substance use disorder (SUD). Children of parents with SUD are at increased risk for language delays, and early supports may help prevent long-term learning challenges. This study will examine whether adding additional supports to group-based parenting intervention improves child language outcomes compared to the group intervention alone.",[29,121,122,30,123],"Substance Use Disorders","Language Disorders in Children","Prevention Intervention",[125,126,127,128],"Naturalistic communication intervention","Parenting","Group based intervention","Vocabulary Acquisition","2026-04-14",{"date":131,"type":42},"2026-04-20",{"date":133,"type":42},"2026-03-10",{"date":135,"type":22},"2029-11-30",{"name":137,"class":49},"University of Oregon",{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":4,"eligibilityCriteria":144,"healthyVolunteers":16,"sex":17,"minAge":145,"maxAge":146,"enrollmentInfo":147,"targetDuration":4,"studyType":149,"phases":4,"briefSummary":150,"conditions":151,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":85},"100633824","cortical-tracking-of-speech-in-the-first-year-of-life-100633824","NCT07531706","Cortical Tracking of Speech in the First Year of Life","Cortical Tracking of Speech in the First Year of Life: a Window Into (a)Typical Language Acquisition","Inclusion Criteria:\n\n* Healthy infants aged between 7 and 8 months\n* Infants with and without familial risk for language disorders (Infants are assigned to the group with familial risk for language disorders if at least one first-degree relative had a certified (clinical) diagnosis of language and\u002For learning disorders).\n* Both parents are native-Italian speakers\n\nExclusion Criteria:\n\n* Gestational age \\\u003C 37 weeks and\u002For birth-weight \\\u003C 2500 grams\n* APGAR scores at birth at 1' and 5' \\\u003C 7\n* Bayley Cognitive Score \\\u003C 7\n* Presence of certified diagnosis of intellectual deficiency, attention-deficit disorder, sensorial and neurological disorders or autism within first-degree relatives.","30 Weeks","34 Weeks",{"count":148,"type":22},50,"OBSERVATIONAL","The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as early predictors of later language development outcomes in infants, including both typical and atypical trajectories.\n\nThe main questions it aims to answer are:\n\n* How do infants with and without a familial history of language and learning impairments differ in their neural ability to track speech and non-speech auditory stimuli at an early stage of development (around 8 months of age)?\n* To what extent do early cortical tracking mechanisms predict later language abilities, including both receptive and expressive skills, measured at approximately 18 months of age? Researchers will compare infants with a familial risk for language and learning impairments (FH+) to infants without such risk (FH-) to determine whether differences in early neural processing of auditory stimuli are associated with later language outcomes.\n\nParticipants will:\n\n* undergo a neurophysiological assessment involving non-invasive electroencephalographic (EEG) recording while being exposed to auditory stimuli, including: speech stimuli (pre-recorded simple stories in Italian, presented in infant-directed speech); non-speech stimuli (musical sounds matched for rhythmic and acoustic properties)\n* take part in a developmental assessment at approximately 8 months of age, including standardized measures of cognitive and early linguistic abilities\n* be involved in a follow-up assessment approximately 10 months later (around 18 months of age), during which standardized tests will evaluate language comprehension and production abilities\n* have additional background information collected, including family history of language and learning disorders and socio-demographic characteristics, to better understand potential risk and protective factors The study follows a longitudinal design and uses non-invasive procedures that do not require active responses from the infant.",[30,152,153,154],"Language Development Disorders","Infant Development","Infant Developmental Assessment","2026-04-09",{"date":157,"type":42},"2026-04-15",{"date":159,"type":42},"2025-10-14",{"date":161,"type":22},"2028-02",{"name":163,"class":49},"IRCCS Eugenio Medea",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":17,"minAge":171,"maxAge":145,"enrollmentInfo":172,"targetDuration":4,"studyType":23,"phases":174,"briefSummary":175,"conditions":176,"keywords":179,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":50},"100557298","the-impact-of-music-medicine-on-preterm-brain-development-and-behavior-100557298","NCT06536296","The Impact of Music Medicine on Preterm Brain Development and Behavior","The Impact of Music Medicine on Preterm Brain Development and Behavior - A Two-Center Randomized Controlled Trial \"The Lullaby Study\"","Inclusion Criteria:\n\n* Very preterm infants born between 24+0 and 30+6 weeks' gestational age (GA) from 2 level III NICUs (Brigham and Women's Hospital, Boston, MA and Yale New Haven, CT)\n* Infants who are medically stable per the clinical care team\n\nExclusion Criteria:\n\n* Infants with major genetic or congenital anomalies known to be associated with developmental delay\n* Infants with severe brain injury (such as intraparenchymal hemorrhage, severe white matter injury)\n* Infants who are severely ill infants for whom MBI is not feasible\n* Infants of parents who cannot complete questionnaires in English or Spanish.","24 Weeks",{"count":173,"type":22},243,[25],"The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.",[153,30,177,178],"Prematurity","Stress",[180,181,182],"Preterm","Neurodevelopment","Music-based Intervention","2026-03-23",{"date":185,"type":42},"2026-03-25",{"date":187,"type":42},"2025-05-19",{"date":189,"type":22},"2031-03-01",{"name":191,"class":49},"Brigham and Women's Hospital",{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":16,"sex":17,"minAge":199,"maxAge":145,"enrollmentInfo":200,"targetDuration":4,"studyType":23,"phases":202,"briefSummary":203,"conditions":204,"keywords":208,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":85},"100505449","combined-oral-motor-stimulation-and-language-on-preterm-infant-feeding-100505449","NCT05861531","Combined Oral Motor Stimulation and Language on Preterm Infant Feeding","The Combined Association of an Oral Motor Stimulation and Language Intervention on Preterm Infant Feeding","Inclusion Criteria:\n\n* 23-30 weeks\n* English and Spanish speaking\n\nExclusion Criteria:\n\n* Major congenital anomalies\n* Surgical necrotizing enterocolitis\n* Non-English and Non-Spanish speaking","23 Weeks",{"count":201,"type":22},124,[25],"This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings, linguistic feedback, and a language curriculum to improve the neonatal inpatient oral feeding and language outcomes for preterm infants.",[29,30,205,206,207],"Feeding; Difficult, Newborn","Mother-Infant Interaction","Maternal Behavior",[209,210,211,212,213,214],"Neonatal feeding","Neonatal language","Oromotor stimulation","Newborn reading","Parent infant interaction","LENA","2025-09-10",{"date":217,"type":42},"2025-09-17",{"date":219,"type":42},"2025-07-01",{"date":221,"type":22},"2030-07-01",{"name":223,"class":49},"Women and Infants Hospital of Rhode Island",{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":230,"eligibilityCriteria":231,"healthyVolunteers":16,"sex":17,"minAge":232,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":23,"phases":236,"briefSummary":237,"conditions":238,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":50},"100552914","talk-with-me-baby-to-enhance-the-early-home-language-environment-100552914","NCT06479278","Talk With Me Baby to Enhance the Early Home Language Environment","Talk With Me Baby: Leveraging Well-Child Care to Enhance the Early Home Language Environment for Rural and Underserved Children","TWMB","Inclusion Criteria:\n\nFor this study, each child-caregiver dyad will consist of:\n\n1. A caregiver who will receive TWMB during routine WCC visits for their child at participating clinics, and\n2. The child of the above caregiver for whom the WCC visits are conducted.\n\nA potential caregiver participant must meet all the following inclusion criteria to enroll in the study:\n\n1. Be the age of majority, or older, as defined by the state of residency.\n2. Able to complete study measures in English.\n3. Have the legal authority to consent to participate for themselves and to consent on behalf of their child.\n\nTo proceed to the follow-up portion of the study the caregiver (dyad) must have a LENA baseline assessment score that is ≤ 75th percentile compared to a child's age-referenced normative data.\n\nA potential child participant must meet all the following inclusion criteria to be enrolled in the study:\n\n1. Receive WCC at a participating clinic from a participating provider.\n2. Be zero to nine months (+ 0-30 days) old at enrollment.\n3. Was born at full term (\\> 37 weeks gestation).\n4. Was born in a singleton birth (i.e., was the only child delivered during the birth).","0 Months","9 Months",{"count":235,"type":22},66,[25],"The goal of this clinical trial is to learn if the Talk With Me Baby (TWMB) program improves the home-language environment for at-risk families with children ages two to six months when primary care providers deliver the program during well-child checkups. The main question it aims to answer is:\n\nWill the TWMB program increase the time a caregiver talks to their infant?\n\nParticipants will:\n\n1. Come to at least four well-child checkups\n2. Receive the TWMB program from the provider during the checkups\n3. Record their conversations with their infant before they receive the program and after they receive the program four times.",[30,239,153,240,241,242],"Speech","Infant Behavior","Language, Child","Language","2025-08-27",{"date":245,"type":42},"2025-08-29",{"date":247,"type":42},"2025-02-03",{"date":249,"type":22},"2026-08-31",{"name":251,"class":252},"IDeA States Pediatric Clinical Trials Network","NETWORK",{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":257,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":16,"sex":17,"minAge":259,"maxAge":260,"enrollmentInfo":261,"targetDuration":4,"studyType":23,"phases":263,"briefSummary":264,"conditions":265,"keywords":268,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":272,"lastUpdatePostDateStruct":273,"startDateStruct":275,"completionDateStruct":277,"leadSponsor":279,"locationsCount":85},"100596663","retrieval-based-word-learning-in-developmental-language-disorder-during-book-reading-ii-100596663","NCT07048392","Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II","Inclusion Criteria:\n\n* a significant deficit in language ability (language test score below cutoff for best sensitivity\u002Fspecificity) or documented age-appropriate language ability.\n* normal hearing.\n* no evidence of neurological damage or disease.\n* scores on tests of nonverbal intelligence above the intellectual disability range\n* not within Autistic range on Autism screening test\n* native English speaker (can be bilingual)\n\nExclusion Criteria:\n\n* failed hearing screening\n* known neurological damage or disease\n* scores on tests of nonverbal intelligence below the intellectual disability range (standard score less than 75)\n* autism spectrum disorder\n* non-native English speaker","48 Months","71 Months",{"count":262,"type":22},32,[25],"Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and eventual economic well-being. Word learning is one of the principal weaknesses in these children. This project focuses on the word learning abilities of four- and five-year-old children with DLD. The goal of the project is to build on the investigators' previous work to determine whether, as has been found thus far, special benefits accrue when these children must frequently recall newly introduced words during the course of learning. In this study, the investigators seek to replicate the advantage that repeated retrieval holds over simple exposure to the words appearing in the context of a story book by increasing the degree to which the words are integrated into the story line.",[266,267,30],"Developmental Language Disorder and Language Impairment","Specific Language Impairment",[269,270,271],"word learning","word retrieval","preschool-aged children","2025-07-03",{"date":274,"type":42},"2025-07-04",{"date":276,"type":42},"2025-03-01",{"date":278,"type":22},"2026-07-31",{"name":280,"class":49},"Purdue University",{"id":282,"slug":283,"hasResults":11,"nctId":284,"briefTitle":285,"officialTitle":285,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":16,"sex":17,"minAge":259,"maxAge":260,"enrollmentInfo":286,"targetDuration":4,"studyType":23,"phases":287,"briefSummary":288,"conditions":289,"keywords":290,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":294,"lastUpdatePostDateStruct":295,"startDateStruct":297,"completionDateStruct":299,"leadSponsor":301,"locationsCount":85},"100592560","retrieval-based-word-learning-in-developmental-language-disorder-adaptive-retrieval-schedule-100592560","NCT06995014","Retrieval-based Word Learning in Developmental Language Disorder: Adaptive Retrieval Schedule",{"count":262,"type":22},[25],"Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and eventual economic wellbeing. Word learning is one of the principal weaknesses in these children. This project focuses on the word learning abilities of four- and five-year-old children with DLD. The goal of the project is to determine whether special benefits accrue when these children must frequently recall newly introduced words during the course of learning. In the current study, the investigators compare a \"standard\" repeated spaced retrieval schedule, with fixed spacing between hearing a word and attempting to retrieve it, to an \"adaptive\" repeated spaced retrieval schedule in which opportunities to retrieve a given word are tailored to the individual child's current knowledge state. The goal of the study is to determine whether the adaptive schedule can increase children's absolute levels of learning while maintaining the advantages of repeated spaced retrieval.",[28,267,30],[291,292,293],"Word learning","Word retrieval","Preschool-aged children","2025-05-28",{"date":296,"type":42},"2025-06-03",{"date":298,"type":42},"2024-08-15",{"date":300,"type":22},"2025-12-31",{"name":280,"class":49},{"id":303,"slug":304,"hasResults":11,"nctId":305,"briefTitle":306,"officialTitle":307,"acronym":308,"eligibilityCriteria":309,"healthyVolunteers":16,"sex":17,"minAge":310,"maxAge":311,"enrollmentInfo":312,"targetDuration":4,"studyType":149,"phases":4,"briefSummary":313,"conditions":314,"keywords":318,"overallStatus":321,"whyStopped":4,"lastUpdateSubmitDate":322,"lastUpdatePostDateStruct":323,"startDateStruct":325,"completionDateStruct":327,"leadSponsor":329,"locationsCount":85},"100484333","hr-eeg-contribution-in-prognostic-evaluation-of-language-development-in-children-with-asd-100484333","NCT05586672","HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD","High Resolution Electroencephalogram Contribution in Prognostic Evaluation of Language Development in Children With Autism Spectrum Disorder","EE-TSA-LANG","Inclusion Criteria:\n\nFor all participants\n\n* Child aged from 3 years to 4 years and half at inclusion.\n* Information delivered and no parental objection for study participation.\n\nFor ASD group\n\n* Diagnosis of ASD according to DSM-V criteria.\n* Expressive language level \\\u003C 27 months regarding on IDE scale.\n\nFor Control group - Matched on age (at +\u002F- 3 months) and gender to ASD group participants.\n\nExclusion Criteria:\n\nFor all participants\n\n* Any illness or treatment that could significantly alter EEG-HR recording (epilepsy, anti-epileptic treatment, psychotropic drugs...).\n* Major hearing or vision disorders.\n\nFor ASD group\n\n\\- Severe and characterised neurological pathology other than ASD\n\nFor Control group\n\n* Characterised neurological or psychiatric pathology.\n* Characteristic language delay.","3 Years","4 Years",{"count":61,"type":22},"The goal of this prospective observational multicentric cohort study is to evaluate the clinical prognostic value of the speech tracking score of language development in children with ASD aged from 3 years to 4 years and half at inclusion.\n\nParticipants will followed during 4 years with an annual visit. During these visits, each participant will be clinically evaluated (scales and tests) and performed an EEG-HR recording. Two groups will be formed, one with children diagnosed with ASD with language delay, and a control group composed of non-ASD children without language delay, matched on age and gender with the ASD group.",[315,30,316,317],"Autism Spectrum Disorder","Neurocognitive Disorders","Child Language",[319,320,315,242],"High Resolution electroencephalogram","Child","NOT_YET_RECRUITING","2022-10-15",{"date":324,"type":42},"2022-10-19",{"date":326,"type":22},"2023-01-02",{"date":328,"type":22},"2028-06-30",{"name":330,"class":49},"Etablissement Public de Santé Barthélemy Durand"]