[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"laparotomy-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:laparotomy-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100611630","phase-4-comparative-efficacy-of-rivaroxaban-and-enoxaparin-in-post-laparotomy-dvt-prevention-100611630",false,"NCT07243080","Comparative Efficacy of Rivaroxaban and Enoxaparin in Post-Laparotomy DVT Prevention","Comparison Between the Efficacy of Rivaroxaban vs Enoxaparin in Post-Operative Deep Venous Thrombosis Prophylaxis After Exploratory Laparotomy","Inclusion Criteria:• Patients aged 18 to 80 years\n\n* Both male or female patients\n* Patients who have undergone emergent exploratory laparotomy for any reason whether traumatic or non-traumatic\n* Patients with expected immobility for more than 24 hours\n\nExclusion Criteria:\n\n* Patients with diagnosed pre-operative DVT\n* BMI more than 40\n* Patient who are on mechanical ventilation post operatively\n* Patient with postoperative Myocardial infarction, ischemic heart disease or cerebrovascular accident\n* Patients who have undergone limb surgery in addition to exploratory laparotomy","ALL","18 Years","80 Years",{"count":20,"type":21},212,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The goal of this clinical trial is to learn if rivaroxaban works better than enoxaparin to prevent deep vein thrombosis (DVT) after emergency exploratory laparotomy in adults. It will also learn about the safety of rivaroxaban compared to enoxaparin.\n\nThe main questions it aims to answer are:\n\nDoes rivaroxaban lower the number of patients who develop DVT after exploratory laparotomy compared to enoxaparin?\n\nWhat medical problems or side effects do participants have when taking rivaroxaban versus enoxaparin?\n\nResearchers will compare rivaroxaban (an oral anticoagulant) to enoxaparin (a subcutaneous injection) to see which drug works better to prevent blood clots after surgery.\n\nParticipants will:\n\nTake rivaroxaban 10 mg orally once daily for 7 days, or enoxaparin 40 mg subcutaneously once daily for 7 days after surgery\n\nUndergo duplex color Doppler ultrasound scans of the legs on day 5 and day 10 after surgery\n\nBe monitored for bleeding, complications, and other side effects",[27,28],"Deep Venous Thromboses","Laparotomy Patients",[30,31,32,33,34,35,36,37,38],"Deep Vein Thrombosis","Exploratory Laparotomy","Rivaroxaban","Enoxaparin","Venous Thromboembolism","Anticoagulation","Prophylaxis","Randomized Controlled Trial","Thromboprophylaxis","RECRUITING","2025-11-19",{"date":42,"type":43},"2025-11-21","ACTUAL",{"date":45,"type":43},"2025-10-10",{"date":47,"type":21},"2025-11-15",{"name":49,"class":50},"Mayo Hospital Lahore","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":60,"minAge":17,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":66,"conditions":67,"keywords":78,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":51},"100609100","pre-habilitation-within-eras-protocol-for-gynecologic-oncology-surgery-the-preeras-study-100609100","NCT07210164","Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study","Prehabilitation With Exercise and Immunonutrition (Ocoxin®) in the Perioperative Management of Gynecologic Malignancies Under ERAS Protocol.","Pre_ERAS","Inclusion Criteria:\n\n* Type of gynecological malignancy: endometrial cancer, ovarian cancer, cervical cancer, treated with laparotomy after the decision of the gynecological-oncology unit (positive opinion of the Multidisciplinary Tumor Board - MDT)\n* Patient age: 18 to 85 years\n* General condition of the patient: ASA score I-III\n* Consent to implement the accelerated recovery protocol - Enhanced recovery after surgery (ERAS)\n* Sufficient understanding of the Greek language\n* Provision of signed, after thorough information, consent to participate in the study\n\nExclusion Criteria:\n\n* Women with performance status: ECOG \\>2 and ASA score \\>III\n* Women who have not been informed and have given written consent","FEMALE","85 Years",{"count":63,"type":21},100,[65],"NA","ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a quicker recovery. In gynecologic cancer surgeries, ERAS has been shown to help patients do better, have fewer problems, and leave the hospital sooner.\n\nA prehabilitation program, in combination with ERAS protocols, aims to optimize patients' physical and psychological condition prior to surgery for gynecological cancers. Interventions may include tailored exercise, nutritional support, respiratory training, and psychological preparation. By enhancing baseline fitness and resilience, prehabilitation improves the body's ability to tolerate surgical stress, reduces complications, and facilitates a faster, smoother recovery within the ERAS framework.",[68,69,70,71,72,73,28,74,75,76,77],"ERAS","Compliance","Quality of Life (QOL)","Excercise","Immunonutrition","Post Operative Pain","Surgical Complication","Gynaecological Malignancies","Gynaecologic Cancer","Gynaecological Oncology",[79,68,80,72],"Prehabilitation","Gynecologic Cancers","2025-09-29",{"date":83,"type":43},"2025-10-07",{"date":85,"type":21},"2025-12-01",{"date":87,"type":21},"2029-12-30",{"name":89,"class":50},"Aristotle University Of Thessaloniki"]