[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"laryngoscopic-stress-response\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:laryngoscopic-stress-response":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100640579","phase-4-dexmedetomidine-vs-lignocaine-for-reducing-intubation-induced-hemodynamic-responses-in-cardiac-surgery-a-randomized-controlled-trial-100640579",false,"NCT07611890","Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial","Comparison of Intravenous Dexmedetomidine and Lignocaine in Reducing Hemodynamic Responses During Laryngoscopy and Endotracheal Intubation In Patients Undergoing Cardiac Surgery at Rawalpindi Institute Of Cardiology- A Randomized Controlled Trial","Inclusion Criteria:\n\nAmerican Society of Anesthesiologists (ASA) physical status III-IV. Patients who are at risk of cardiovascular events\n\nExclusion Criteria:\n\n1. Patients with known hypersensitivity to dexmedetomidine and Lignocaine.\n2. Patients on medications that could interfere with the study (e.g., beta-blockers, calcium channel blockers).\n3. Pregnant or lactating women.\n4. Patients with a history of airway anomalies or difficult intubation.","ALL","18 Years","65 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.",[27,28,29],"Laryngoscopic Stress Response","Dexmedetomidine","Lignocaine",[31,28,29,32],"Laryngoscopic stress response","Cardiac surgery","RECRUITING","2026-05-21",{"date":36,"type":37},"2026-05-28","ACTUAL",{"date":34,"type":37},{"date":40,"type":21},"2026-08-21",{"name":42,"class":43},"Rawalpindi Institute of Cardiology","OTHER"]