[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"laser\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:laser":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,47,79,101,125,148,175,201],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100641584","comparison-of-eryag-assisted-laser-crown-lengthening-against-surgical-crown-lengthening-100641584",false,"NCT07653802","Comparison of Er:YAG Assisted Laser Crown Lengthening Against Surgical Crown Lengthening","Comparison of Er:YAG Assisted Laser Crown Lengthening Against Surgical Crown Lengthening: a Longitudinal Study.","* Inclusion criteria:\n\n  1. Teeth indicated for crown lengthening procedure either in the maxillary or mandibular arch.\n  2. Patients in the age group of 18-75 years.\n* Exclusion criteria:\n\n  1. Patients with uncontrolled diabetes mellitus. Uncontrolled diabetes mellitus diagnosed with HbA1C ≥ 7% will be an exclusion criterion.\n  2. Smokers (considered as smoking ≥ 10 cigarettes\u002Fday)\n  3. Pregnant women\n  4. Patients with uncontrolled systemic diseases that may affect the healing of soft and hard tissues of the periodontium will be excluded.",true,"ALL","20 Years","70 Years",{"count":21,"type":22},26,"ESTIMATED","INTERVENTIONAL",[25],"NA","Crown lengthening is a clinical procedure that involves reshaping the gingiva, and sometimes bone, in order to expose more of tooth's structure. The procedures is performed for both functional and aesthetic reasons. In certain instances, this procedure is performed to This procedure is commonly performed for both functional and aesthetic reasons, such as to prepare a tooth for a crown or to enhance the appearance of a smile. Traditional crown lengthening techniques typically involve surgical methods that can be invasive, leading to extended recovery times and postoperative discomfort in this study we compare traditional versus the laser aided crown lengthening to compare the periodontal parameters in both cases.",[28,29,30,31],"Crown Lengthening","Crown Lengthening Procedure With Ostectomy","Laser","Piezoelectric Technique",[33],"crown lengthening","RECRUITING","2026-06-16",{"date":37,"type":38},"2026-06-17","ACTUAL",{"date":40,"type":38},"2025-07-01",{"date":42,"type":22},"2026-09-30",{"name":44,"class":45},"Gulf Medical University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":46},"100636501","high-energy-laser-in-the-conservative-treatment-of-rhizarthrosis-100636501","NCT07566507","High-Energy Laser in the Conservative Treatment of Rhizarthrosis","High Intensity Laser Therapy (HL) vs Exercise in Thumb Osteoarthritis","HLEX-TO","Inclusion Criteria:\n\n* arthrosis of the trapezoid-metacarpal with stage 1 or 2 of the Eaton-Littler radiographic classification and pain (recent radiograph within 6 months previously);\n* clinical picture that has been occurring for at least 6 months;\n* pain scored with VAS scale at least 4\u002F10.\n\nExclusion Criteria:\n\n* rheumatoid arthritis or outcomes of trauma in the affected area, contra-indications to treatment with laser therapy (neoplasia, pregnancy, thrombocytopenia, epilepsy, uncompensated heart disease or arrhythmia, pacemaker, local infections),\n* corticosteroid infiltration or physical therapy in the previous 4 weeks.","18 Years",{"count":57,"type":22},42,[25],"Osteoarthritis (OA) is a degenerative joint disease that can affect the hands and is particularly debilitating when it involves the trapeziometacarpal joint (rhizarthrosis). It causes pain, deformity, limited movement and strength, joint instability, resulting in significant limitations in daily activities.Many conservative treatments, such as medications, therapeutic exercises, physical therapy, and orthoses, are effective for managing hand OA. For patients who do not respond to conservative treatments, surgical intervention will be necessary.",[61,62,30,63],"Thumb Osteoarthritis","Hand Injuries","Exercise",[65,66,67,68,69],"hand","rehabilitation","conservative","lasertherapy","exercise","2026-05-13",{"date":72,"type":38},"2026-05-15",{"date":74,"type":38},"2025-11-01",{"date":76,"type":22},"2028-12-01",{"name":78,"class":45},"Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":23,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":46},"100632879","different-laser-frequencies-on-neuropathic-outcomes-in-patients-with-bells-palsy-100632879","NCT07519421","Different Laser Frequencies on Neuropathic Outcomes in Patients With Bell's Palsy","Inclusion Criteria:\n\n1. Eighty subjects from both genders diagnosed with Bell's palsy will be recruited through direct referrals from their independent physician's neurology department.\n2. Subjects aged 18 and above from all genders\n3. Unilateral Bell's palsy either on the right or left side.\n4. The Facial disability index will be used for assessment and progression of Bell's palsy before and after treatment protocol.\n5. Patients will on level II, III, IV and V of House-Brackmann scale.\n\nExclusion Criteria:\n\n1. We will exclude patients who had central nervous system pathology, sensory loss over the face, or recurrence of facial palsy.\n2. Upper motor neuron fascial nerve palsy.\n3. Any infant or child (\\\u003C18 years).\n4. Bilateral Facial nerve palsy\n5. Severe hypertension (Blood pressure more than 200\u002F120 mmHg).",{"count":86,"type":22},80,[25],"this study was done to compare different laser frequencies on neuropathic outcomes in patients with Bell's palsy.",[90,91,30],"Neuropathy, Facial","Bell Palsy","2026-04-02",{"date":94,"type":38},"2026-04-09",{"date":96,"type":38},"2025-12-01",{"date":98,"type":22},"2026-06-15",{"name":100,"class":45},"Kafrelsheikh University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":16,"sex":17,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":23,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":46},"100628923","comparative-effectiveness-of-long-pulsed-1064-nm-ndyag-and-fractional-co-laser-in-skin-rejuvenation-100628923","NCT07467954","Comparative Effectiveness of Long-Pulsed 1064-nm Nd:YAG and Fractional CO₂ Laser in Skin Rejuvenation","A Comparative Split-Face Study of Long-Pulsed 1064-nm Nd:YAG and Fractional CO₂ Laser for Skin Rejuvenation Based on Dermal Thickness, Skin Elasticity, Wrinkle Assessment, and Global Aesthetic Improvement Scale Scores","Inclusion Criteria:\n\n* Male and female patients with skin aging classified as Glogau scale II-III\n* Age 30-59 years.\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women.\n* Active smokers.\n* Individuals with high levels of sun exposure.\n* History of facial laser therapy, microdermabrasion, chemical peeling, botulinum toxin injection, microneedling, or skin booster injections within the past six months.\n* Use of oral isotretinoin within the past six months.\n* Use of topical retinoids or their derivatives, topical vitamin C, or other collagen-stimulating and skin-rejuvenating agents within the past two weeks.\n* Use of oral vitamin C, collagen-stimulating supplements, antioxidants, or hormone therapy with skin-rejuvenating effects within the past one month.\n* Presence of active facial skin inflammation.\n* History of keloid formation.\n* History of allergy to topical lidocaine anesthesia.","30 Years","59 Years",{"count":111,"type":22},15,[25],"Skin rejuvenation is an effort to improve skin condition from the signs of skin aging. Skin aging is a complex biological process influenced by intrinsic and extrinsic factors, leading to changes in the epidermis and dermis, including decreased collagen characterized by dermal thinning, as well as alterations in skin appearance such as laxity and wrinkles. Laser therapy is one of the treatment modalities for skin rejuvenation, aiming to induce neocollagenesis and collagen remodeling, resulting in dermal thickening and improvement in skin appearance. Fractional CO₂ laser is an ablative laser considered the gold standard therapy for skin rejuvenation, whereas Long Pulsed (LP) Nd:YAG 1064 nm is a nonablative laser that is also used for skin rejuvenation. To date, there have been no studies evaluating the comparative effectiveness between fractional CO₂ laser and LP Nd:YAG 1064 nm for skin rejuvenation. Therefore, research comparing the effectiveness of fractional CO₂ laser and LP Nd:YAG 1064 nm for skin rejuvenation is needed, assessed based on dermal thickness, skin elasticity, wrinkles, and Global Aesthetic Improvement Scale scores.",[115,30],"Skin Rejuvenation","2026-03-08",{"date":118,"type":38},"2026-03-12",{"date":120,"type":38},"2025-10-14",{"date":122,"type":22},"2026-04-16",{"name":124,"class":45},"Universitas Padjadjaran",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":131,"minAge":18,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":23,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":46},"100619986","effect-of-laser-acupoints-on-fallopian-tube-obstruction-100619986","NCT07351747","Effect of Laser Acupoints on Fallopian Tube Obstruction","Inclusion Criteria:\n\n* Women aged 20-35 years - nulliparous.\n* Women diagnosed with fallopian tube obstruction.\n* Body mass index less than 30 kg\u002Fm2.\n* Consent to participate in the study.\n* General good health with no major co-existing medical conditions that could interfere with the treatment or outcomes.\n* No prior fertility treatments \\[e.g., In vitro fertilization (IVF), intrauterine insemination (IUI)\\] within the last 6 months.\n* Ability to attend all scheduled sessions and follow-up assessments.\n\nExclusion Criteria:\n\n* Currently pregnant or breastfeeding.\n* History of pelvic surgery within the past year.\n* Presence of severe systemic diseases such as active cancer or severe cardiovascular diseases.\n* History of allergic reactions or adverse responses to acupuncture or laser therapies.\n* Currently undergoing hormonal therapy or use of hormonal contraceptives.\n* Current or recent history of genital tract infections, including sexually transmitted. infections, which could affect the reproductive system.\n* Presence of significant uterine anomalies diagnosed through imaging that could impact fertility.\n* Polycystic Ovary Syndrome (PCOS).","FEMALE","35 Years",{"count":134,"type":22},36,[25],"This study aims to determine the efficacy of laser acupoint therapy on treating fallopian tube obstruction.",[30,138,139],"Acupoints","Fallopian Tube Obstruction","2026-01-10",{"date":142,"type":38},"2026-01-20",{"date":144,"type":38},"2025-04-01",{"date":146,"type":22},"2026-04-01",{"name":100,"class":45},{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":16,"sex":17,"minAge":154,"maxAge":155,"enrollmentInfo":156,"targetDuration":4,"studyType":23,"phases":158,"briefSummary":159,"conditions":160,"keywords":163,"overallStatus":165,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":4},"100592884","evaluation-of-the-effect-of-laser-therapy-on-lateral-pterygoid-muscle-in-patients-with-wilkes-stage-i-and-ii-temporomandibular-disorders-tmd-case-series-study-100592884","NCT06999239","Evaluation of the Effect of Laser Therapy on Lateral Pterygoid Muscle in Patients With Wilke's Stage I and II Temporomandibular Disorders (TMD): Case Series Study","Inclusion criteria:\n\n1. Patients age between 16-50 years with no sex predilection.\n2. Patients who will be free from any systemic diseases that affect temporomandibular joint.\n3. Patients who will be diagnosed with wilk's stage I and II temporomandibular disorders (TMD).\n4. Patients who will be ready to give informed consent.\n\nExclusion Criteria:\n\n1. Patients with previous temporo-mandibular surgeries.\n2. Patients with previous facial fracture.\n3. Patients who will be under another type of treatment for TMD (e.g., occlusal splints, pharmacological drugs, or head and neck surgery).\n4. Patients who will not attend the proposed treatment sessions or follow-up visits.","16 Years","50 Years",{"count":157,"type":22},25,[25],"The purpose of this study will be to evaluate the effect of laser therapy on lateral pterygoid muscle in patients with Wilke's stage I and II temporomandibular disorders (TMD).",[30,161,162],"Temporomandibular Joint Disorders","Lateral Pterygoid Muscle",[164],"laser therapy, lateral pterygoid muscle, Wilke's, stage I and II, TMD.","NOT_YET_RECRUITING","2025-06-10",{"date":168,"type":38},"2025-06-13",{"date":170,"type":22},"2025-07",{"date":172,"type":22},"2026-08",{"name":174,"class":45},"Cairo University",{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":4,"eligibilityCriteria":181,"healthyVolunteers":11,"sex":182,"minAge":183,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":186,"phases":4,"briefSummary":187,"conditions":188,"keywords":190,"overallStatus":165,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":4},"100586487","focal-laser-ablation-in-prostate-cancer-100586487","NCT06916013","Focal Laser Ablation in Prostate Cancer","Transperineal Targeted Focal Laser Ablation of Localized Intermediate Risk Prostatic Adenocarcinoma (Pilot Study)","Inclusion Criteria:\n\n* Prostate cancer visible on mpMRI or PSMA PET\u002FCT and positive in the targeted biopsy.\n* Gleason score 7 (ISUP grade 2\u002F3)\n* PSA 10-20 ng\u002FmL\n* Clinical stage T2b\n* Refusing radical prostatectomy.\n\nExclusion Criteria:\n\n* Prostate cancer invisible on mpMRI or PSMA PET\u002FCT but positive in the systematic biopsies.\n* Presence of \\>2 MRI-visible lesions and positive in the biopsies.\n* Extracapsular extension\n* Seminal vesicle invasion\n* Presence of metastases detected by imaging\n* Gleason Score \\> 7\n* Stage \\> T2b\n* PSA \\> 20 ng\u002FmL\n* Urinary tract infection (UTI)\n* Severe lower urinary tract symptoms defined as an IPSS \\>20\n* Severe coagulation disorders\n* Inadequate compliance\n* Contraindications to MRI\n* Paramagnetic contrast agent allergy\n* Acute and\u002For chronic renal failure","MALE","45 Years",{"count":185,"type":22},30,"OBSERVATIONAL","To assess the effectiveness of MRI-US or PSMA PET\u002FCT-U\u002FS fusion-guided focal laser ablation (FLA) for the treatment of a localized, intermediate-risk prostate cancer in terms of short-term oncological \\& functional outcomes.",[189,30],"Prostate Cancer",[191,30],"Prostate cancer","2025-04-04",{"date":194,"type":38},"2025-04-08",{"date":196,"type":22},"2025-04-20",{"date":198,"type":22},"2027-08-20",{"name":200,"class":45},"Ain Shams University",{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":209,"enrollmentInfo":210,"targetDuration":4,"studyType":186,"phases":4,"briefSummary":212,"conditions":213,"keywords":4,"overallStatus":165,"whyStopped":4,"lastUpdateSubmitDate":216,"lastUpdatePostDateStruct":217,"startDateStruct":219,"completionDateStruct":221,"leadSponsor":223,"locationsCount":4},"100567520","evaluating-qol-and-postoperative-complications-using-tetha-technique-in-the-treatment-of-tributary-veins-100567520","NCT06669260","Evaluating QoL and Postoperative Complications Using TEThA Technique in the Treatment of Tributary Veins","Prospective Study to Evaluate QoL Scores and Post-operative Complications Using TEThA (Transfixing Endovenous Thermal Ablation) Technique in Tributary Veins Treatment","TEThA","Inclusion Criteria:\n\nPatients with varicose veins \\> 2mm associated with reflux of great or small saphenous veins with CEAP C2 to C6\n\nExclusion Criteria:\n\nPatients under 18 years Acute or previous thrombophlebitis or deep vein thrombosis. Pregnant patient. Reject the Informed Consent Form.","90 Years",{"count":211,"type":22},20,"Endovenous laser thermoablation is a well-established alternative for the treatment of tributary veins. We believe that it is possible to improve the techniques described in the literature, aiming not only to allocate the laser fiber within the venous lumen, but mainly to transfix the vessel walls - a technique called TEThA (Transfixing Endovenous Thermal Ablation).",[214,215,30],"Varicose Veins","Quality of Life","2024-10-30",{"date":218,"type":38},"2024-11-01",{"date":220,"type":22},"2024-11-21",{"date":222,"type":22},"2025-07-22",{"name":224,"class":45},"Nara Medeiros Cunha de Melo Vasconcelos"]