[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"late-life-prodromal-depression\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:late-life-prodromal-depression":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100607243","effects-of-mindfulness-or-brain-stimulation-intervention-for-late-life-adults-in-taiwan-urban-and-rural-areas-100607243",false,"NCT07186023","Effects of Mindfulness or Brain Stimulation Intervention for Late-life Adults in Taiwan Urban and Rural Areas","Intervention Evaluation for Late-life Depression in Taiwan Urban and Rural Areas: Long-term Tracking and Prediction of Non-pharmaceutical Interventions by Smart AI Technologies","PredictNPI","Inclusion Criteria for individuals participating in mindfulness-based Interventions:\n\n* Literate or have received an education above the elementary level.\n* Have normal or corrected vision and hearing, able to communicate and understand explanations.\n* Right-handed individuals as assessed by the Edinburgh Handedness Inventory.\n\nExclusion Criteria for individuals participating in mindfulness-based Interventions:\n\n* Individuals with dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease.\n* Individuals with neurological system disorders.\n* Individuals with alcohol or drug dependence.\n* Individuals with other major physical illnesses, such as diabetes, heart failure, or endocrine abnormalities, or those who have experienced an acute myocardial infarction within the past three months.\n* Individuals with metal objects in the body that cannot undergo magnetic resonance imaging (MRI), such as cardiac pacemakers, vascular clips, hearing aids, artificial joints, steel pins, etc.\n* Individuals with Claustrophobia.\n* Individuals in pregnancy or possibility of pregnancy.\n\nInclusion Criteria for individuals participating in brain stimulation Intervention:\n\n* Individuals diagnosed with major depressive disorder by psychiatrists according to the Diagnostic and Statistical Manual, and who can cooperate with the psychiatric outpatient clinic regulations.\n* Literate or have received an education above the elementary level.\n* Have normal or corrected vision and hearing, able to communicate and understand explanations.\n* Right-handed individuals as assessed by the Edinburgh Handedness Inventory.\n* Individuals are prescribed brain stimulation therapy by clinical physicians.\n\nExclusion Criteria for individuals participating in brain stimulation Intervention:\n\n* Individuals with dementia, stroke, cerebrovascular disease, brain injury, epilepsy, or Parkinson's disease.\n* Individuals with neurological system disorders.\n* Individuals with alcohol or drug dependence.\n* Individuals with other major physical illnesses, such as diabetes, heart failure, or endocrine abnormalities, or those who have experienced an acute myocardial infarction within the past three months.\n* Individuals with metal objects in the body that cannot undergo magnetic resonance imaging (MRI), such as cardiac pacemakers, vascular clips, hearing aids, artificial joints, steel pins, etc.\n* Individuals with Claustrophobia.\n* Individuals in pregnancy or possibility of pregnancy.",true,"ALL","55 Years",{"count":21,"type":22},124,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled trial will examine the effects of mindfulness-based interventions and brain stimulation interventions on cognitive function and psychological well-being in older adults. The study will employ a comprehensive assessment approach incorporating psychological evaluations, behavioral assessments, psychophysiological measurements, and neuroimaging analyses to characterize the outcome of nonpharmaceutical interventions in improving geriatric well-being or reducing depression severity.",[28,29,30,31,32],"Late-Life Adults","Late-Life Prodromal Depression","Late-Life Depression","Mindfulness","Brain Stimulation Intervention","RECRUITING","2025-09-15",{"date":36,"type":37},"2025-09-22","ACTUAL",{"date":39,"type":37},"2025-08-01",{"date":41,"type":22},"2028-12",{"name":43,"class":44},"National Health Research Institutes, Taiwan","OTHER",2]