[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ldl-hyperlipoproteinemia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ldl-hyperlipoproteinemia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":42,"locationsCount":4},"100605081","gingival-crevicular-fluid-oxidized-low-density-lipoprotein-levels-in-health-and-stage-iiiiv-periodontitis-100605081",false,"NCT07157878","Gingival Crevicular Fluid Oxidized Low-Density Lipoprotein Levels in Health and Stage III\u002FIV Periodontitis","Gingival Crevicular Fluid Oxidized Low-Density Lipoprotein Levels in Health and Stage III\u002FIV Periodontitis: A Cross-Sectional Comparative Study","LDL in GCF","Inclusion Criteria:\n\n* For all participants (applies to both groups):\n\n  1. Age 30-60 years.\n  2. Systemically healthy (based on medical history and physician clearance, if needed).\n  3. No history of periodontal treatment within the last 6 months.\n\nExclusion Criteria:\n\n* 1\\. History of systemic diseases affecting periodontium (e.g., uncontrolled diabetes, autoimmune diseases, osteoporosis).\n\n  2\\. Current or past diagnosis of Alzheimer's disease or other neurodegenerative disorders.\n\n  3\\. Use of medications affecting periodontal status (e.g., immunosuppressants, long-term corticosteroids, anticonvulsants).\n\n  4\\. Antibiotic or anti-inflammatory therapy within the past 3 months. 5. Current smokers or history of smoking in the past year.","ALL","30 Years","65 Years",{"count":21,"type":22},40,"ESTIMATED","2 Days","OBSERVATIONAL","Periodontitis is a chronic, multifactorial inflammatory disease primarily caused by dysbiotic plaque biofilms, characterized by the progressive destruction of the supporting structures of the teeth. In advanced stages (Stage III\u002FIV), periodontitis leads to significant attachment and bone loss, often culminating in tooth loss and a negative impact on the patient's quality of life. Recent evidence has emphasized the systemic implications of periodontal inflammation, suggesting a bidirectional relationship between periodontitis and various systemic conditions, especially cardiovascular diseases",[27,28],"Periodontal Diseases","LDL Hyperlipoproteinemia",[30,31,32,33],"Periodontitis","LDL","GCF","periodontal health","NOT_YET_RECRUITING","2025-09-02",{"date":37,"type":38},"2025-09-05","ACTUAL",{"date":40,"type":22},"2025-09-15",{"date":40,"type":22},{"name":43,"class":44},"shaimaa hamdy","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100556508","cholesterol-self-testing-in-patients-post-acute-coronary-syndrome-100556508","NCT06526013","Cholesterol Self-testing in Patients Post Acute Coronary Syndrome","C-Check","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Patients with acute coronary syndrome in the last 6 months and not having reached the LDL target value\n* Signed informed consent\n\nExclusion Criteria:\n\n* Persons unable to understand the study\n* Persons unable or unwilling to perform self-measurements\n* Persons unable or unwilling to undergo additional cholesterol-lowering therapy to reach the LDL target\n* Pre-menopausal women without contraception\n* Use of experimental drugs or investigational products within 30 days prior to screening\n* Employees or contractors of the institution conducting the study or family members of the Principal Investigator, Co-Investigator, or financial supporter","18 Years",{"count":54,"type":22},200,"INTERVENTIONAL",[57],"NA","The pharmacological reduction of LDL-C lowers cardiovascular risk and is therefore a priority in cardiovascular secondary prevention. The achievement of LDL-C target levels in Germany, Europe, and worldwide is inadequate, despite a wide array of lipid-lowering medications. Only a small proportion of post-myocardial infarction patients reach their LDL-C target range within a year. There is a significant need for new strategies to improve LDL-C target achievement and thereby reduce the occurrence of secondary cardiovascular events.\n\nThe aim of the study is to establish a basis for improving prevention by achieving the target LDL level effectively and quickly in patients with high and very high cardiovascular risk profiles.",[60,61,28,62],"Acute Coronary Syndrome","Prevention","Therapeutic Adherence",[60,64,65,66,67],"Dyslipidemia","Statin","Lipid lowering therapy","Cardiovascular disease","RECRUITING","2024-07-30",{"date":71,"type":38},"2024-08-01",{"date":73,"type":38},"2024-06-01",{"date":75,"type":22},"2025-09-30",{"name":77,"class":44},"University of Leipzig",1]