[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"leakage-testing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:leakage-testing":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100582617","efficacy-and-safety-of-colorectal-anastomotic-leak-testing-100582617",false,"NCT06865638","Efficacy and Safety of Colorectal Anastomotic Leak Testing","A Comparative Study of Clinical Outcomes Between Leak Testing and No Leak Testing for Anastomosis in Colorectal Cancer Surgery: a Multicenter, Stratified Randomized Controlled Trial.","Inclusion Criteria:\n\n1. Patients diagnosed with colorectal cancer by pathology and scheduled for surgical treatment who meet the surgical indications.\n2. Aged between 18 and 85 years.\n3. American Society of Anesthesiologists (ASA) physical status classification is I - III.\n4. The patient or his\u002Fher legal representative can understand and sign the informed consent form and is willing to cooperate throughout the study process.\n\nExclusion Criteria:\n\n1. Patients with preoperatively diagnosed anastomotic leak or other severe abdominal infections.\n2. Patients with severe cardiovascular and cerebrovascular diseases (such as recent myocardial infarction, unstable angina pectoris, severe heart failure, acute cerebral infarction, etc.) who cannot tolerate surgery and related tests.\n3. Patients with severely impaired liver and kidney function (liver function Child - Pugh classification C or above, creatinine clearance rate \\\u003C 30 ml\u002Fmin).\n4. Patients with coagulation disorders (such as platelet count \\\u003C 50×10⁹\u002FL, international normalized ratio (INR) \\> 1.5, etc.) that cannot be corrected or are receiving anticoagulant therapy that cannot be adjusted.\n5. Patients with a history of abdominal radiotherapy or multiple abdominal surgeries and severe abdominal adhesions that may affect the operation and detection procedures.\n6. Patients with other malignant tumors who are receiving active anti-tumor treatment such as radiotherapy and chemotherapy.\n7. Patients with mental illness or cognitive impairment who cannot cooperate with the study process and follow-up.","ALL","18 Years","85 Years",{"count":20,"type":21},264,"ESTIMATED","INTERVENTIONAL",[24],"NA","To evaluate the effectiveness of the gastroscopy, air, and methylene blue (GAM) leak testing in reducing the incidence of postoperative anastomotic complications, especially anastomotic leakage, in patients with colorectal cancer. The primary outcomes included is the incidence of anastomotic complications (mainly anastomotic leak) within 30 days after surgery",[27,28,29,30,31],"Colorectal Cancer","Leakage Testing","Colorectal Surgery","Complications","Anastomotic Leakage","RECRUITING","2026-03-29",{"date":35,"type":36},"2026-03-31","ACTUAL",{"date":38,"type":36},"2024-12-22",{"date":40,"type":21},"2029-04-01",{"name":42,"class":43},"Nanchong Central Hospital","OTHER_GOV",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":44},"100608765","comparison-of-leakage-in-endodontically-treated-teeth-obturated-with-different-types-of-gutta-percha-coatings-and-bioceramic-sealer-100608765","NCT07205809","Comparison of Leakage in Endodontically Treated Teeth Obturated With Different Types of Gutta Percha Coatings and Bioceramic Sealer","In Vitro Comparison of Leakage in Endodontically Treated Teeth Obturated With Different Types of GP Coatings Using Bioceramic Sealer: A Randomized Controlled Trial.","Inclusion Criteria:\n\n1\\. Extracted human teeth with single canal and mature root apex\n\nExclusion Criteria:\n\n1. Teeth with calcified (non-negotiable) canals.\n2. Teeth with internal\u002Fexternal root resorption (as seen on radiograph)\n3. Teeth with caries extending to the floor of pulp chamber.\n4. Teeth with a single canal but open apex.",true,{"count":54,"type":21},60,[24],"In vitro study to compare the sealing ability of bioceramic-coated gutta-percha with bioceramic sealer against conventional gutta-percha with bioceramic sealer in root canal obturation. A total of 60 extracted human single-canal teeth will be prepared and obturated according to standardized protocols, then evaluated for microleakage. Data will be analyzed using SPSS (version 25) with appropriate non-parametric tests at a significance level of p\\\u003C0.05. The outcomes are expected to identify the more effective obturation material combination in achieving a fluid-tight seal, thereby contributing to improved success rates in endodontic therapy.",[28],[59,60,61,62],"leakage","gutta percha","bioceramic","sealer","NOT_YET_RECRUITING","2025-09-26",{"date":66,"type":36},"2025-10-03",{"date":68,"type":21},"2025-11-05",{"date":70,"type":21},"2026-06-12",{"name":72,"class":43},"Pakistan Institute of Medical Sciences"]