[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"leishmaniasis-brazilian\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:leishmaniasis-brazilian":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100519203","phase-2-pilot-study-oral-treatment-of-american-tegumentary-leishmaniasis-cutaneous-and-mucosal-forms-in-the-elderly-100519203",false,"NCT06040489","Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly","Inclusion Criteria:\n\n* Active confirmed cutaneous leishmaniasis ou mucosal leishmaniasis\n* Use of highly effective contraceptive method and a negative serologic pregnancy test (beta - HCG), if female in fertile phase\n* Agree and sing informed consent form\n\nExclusion Criteria:\n\n* Previous treatment with leishmanicidal drugs in the last 6 months\n* Pre-treatment electrocardiographic changes that contraindicate the use of liposomal amphotericin B (QTc greater than 450ms)\n* Serum creatinine or urea 1.5 times the upper limit of normal\n* Patients with severe or decompensated liver, kidney, heart disease, Diabetes Mellitus\n* history of any hypersensitivity reaction to liposomal amphotericin B, miltefosine and\u002For pentoxifylline\n* Pregnant and breastfeeding women\n* Patients with Acquired Immunodeficiency Syndrome (AIDS) or other immunodeficiency","ALL","50 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22,23],"PHASE2","PHASE3","Randomised clinical trial comparing oral miltefosine associated with pentoxifylline to intravenous liposomal amphotericin b for the treatment of cutaneous and mucosal leishmaniasis",[26,27],"Leishmaniasis; Brazilian","Leishmaniasis, Mucocutaneous",[29,30,31,32,33,34],"Elderly","Miltefosine","Leishmaniasis","Pentoxifylline","Liposomal amphotericin b","Treatment","RECRUITING","2023-09-13",{"date":38,"type":39},"2023-09-15","ACTUAL",{"date":41,"type":39},"2022-06-22",{"date":43,"type":19},"2026-06",{"name":45,"class":46},"University of Brasilia","OTHER"]