[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"leishmaniasis-visceral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:leishmaniasis-visceral":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100631751","leish-ped-study-on-leishmaniasis-in-children-100631751",false,"NCT07504757","LEISH-PED: Study on Leishmaniasis in Children","A Multicenter Study on Leishmaniasis in Children: Clinical and Epidemiological Characteristics and Outcomes","LEISH-PED","Inclusion Criteria:\n\n* Patients younger than 18 years of age at the time of diagnosis\n* Diagnosis of human leishmaniasis according to World Health Organization (WHO) criteria\n* Written informed consent signed by parents or legal guardians; patient assent when applicable\n\nExclusion Criteria:\n\n* Patients who do not meet the diagnostic criteria for confirmed human leishmaniasis\n* Lack of informed consent signed by parents or legal guardians, when required","ALL","17 Years",{"count":20,"type":21},200,"ESTIMATED","OBSERVATIONAL","Leishmaniasis is an infection caused by Leishmania parasites. In children, it can affect the skin or internal organs. Diagnosis may be delayed because the signs and symptoms can be similar to those of other conditions. Delayed diagnosis or treatment may lead to worse outcomes. Treatment approaches, especially for cutaneous leishmaniasis, may also vary across centers. This study aims to improve knowledge about pediatric leishmaniasis in Italy.\n\nThis is a multicenter observational study in children younger than 18 years of age with a diagnosis of human leishmaniasis according to World Health Organization criteria. The study includes both retrospective and prospective data from participating centers in Italy. Researchers will collect and analyze clinical, diagnostic, epidemiological, treatment, and outcome data from the baseline visit and from follow-up during the first year.\n\nThe main goal of the study is to describe the clinical and epidemiological features of pediatric leishmaniasis in Italy over the study period, with a particular focus on diagnostic and treatment delay and on patient outcomes. The study will also assess the frequency and severity of disease over time and compare outcomes associated with different treatment approaches, particularly in cutaneous leishmaniasis. Patients evaluated between January 1, 2013 and June 30, 2031 may be included.",[25,26,27,28],"Leishmania Infantum Disease","Leishmaniasis, Visceral","Leishmaniasis, Cutaneous","Leishmaniasis, Mucocutaneous",[30,31,32,33,34,35,36,37],"Pediatric leishmaniasis","Visceral leishmaniasis","Cutaneous leishmaniasis","Mucocutaneous leishmaniasis","Children","Italy","Diagnostic delay","Leishmania infantum","RECRUITING","2026-03-26",{"date":41,"type":42},"2026-04-01","ACTUAL",{"date":44,"type":42},"2025-01-30",{"date":46,"type":21},"2031-12-30",{"name":48,"class":49},"Meyer Children's Hospital IRCCS","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100577039","visceral-leishmaniasis-in-emilia-romagna-leishmania-2019-100577039","NCT06793111","Visceral Leishmaniasis in Emilia-Romagna (Leishmania-2019)","Visceral Leishmaniasis in Emilia-Romagna","Inclusion Criteria:\n\n* Patients of any age with microbiologically established diagnosis of LV.\n* Obtaining Informed Consent.\n\nExclusion Criteria:\n\n* not having obtained Informed Consent","6 Years","90 Years",{"count":61,"type":21},300,"According to reports in the literature, from 2012 to date, there has been an increase in the number of diagnosed cases of autochthonous visceral Leishmania in the Province of Bologna.\n\nIn this context, it was decided to carry out a retrospective prospective observational study, which is essential to describe the epidemiology of LV in order to outline the scientific and rational bases necessary for the drafting of guidelines to standardise the diagnostic and therapeutic approach to this disease, in order to reduce the diagnostic delay and improve therapeutic results.\n\ntherapeutic outcome. In addition, epidemiological data will make it possible to identify possible new strategies to control the disease, which are essential for reducing its transmission.",[26],[65],"Leishmaniasis","2025-01-20",{"date":68,"type":42},"2025-01-27",{"date":70,"type":42},"2020-04-21",{"date":72,"type":21},"2025-12-31",{"name":74,"class":49},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",5]