[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"length-of-hospital-stay\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:length-of-hospital-stay":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,52,86,117,140,170],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100630886","virtual-reality-for-postoperative-recovery-after-major-abdominal-surgery-100630886",false,"NCT07493499","Virtual Reality for Postoperative Recovery After Major Abdominal Surgery","Effect of Virtual Reality on Quality of Recovery and Hospital Stay After Major Abdominal Surgery","VR-RECOVER","Inclusion Criteria:\n\n* Adult patients aged 18 to 60 years.\n* Scheduled for elective major abdominal surgery (e.g., colorectal, gastric, or hepatobiliary procedures).\n* Physical and cognitive ability to provide informed consent.\n* Ability to use and interact with Virtual Reality (VR) equipment (head-mounted display).\n* Followed the standardized Enhanced Recovery After Surgery (ERAS) protocol at the hospital.\n\nExclusion Criteria:\n\n\\- Patients with a history of epilepsy or photosensitive seizures.\n\n* Significant cognitive impairment or diagnosed psychiatric disorders that may interfere with study participation.\n* Severe visual or auditory impairments that prevent effective interaction with VR content.\n* Patients with pre-existing motion sickness or severe vertigo.\n* Presence of open wounds or infections in the head or face area that prevent wearing the VR headset.","ALL","18 Years","60 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","Major abdominal surgery often leads to significant postoperative pain, anxiety, and prolonged hospital stays, which can delay overall recovery. This study aims to evaluate the effectiveness of immersive Virtual Reality (VR) as a non-pharmacological intervention to enhance the quality of recovery and reduce the length of hospital stay. Patients in the intervention group will engage in standardized VR sessions featuring guided relaxation and mindfulness-based stress reduction, starting from the evening before surgery through the third postoperative day. The study compares this VR-enhanced protocol against standard perioperative care within an Enhanced Recovery After Surgery (ERAS) framework. The findings are expected to determine if VR can serve as a feasible and effective tool to improve clinical outcomes and patient well-being in surgical wards.",[28,29,30,31],"Abdominal Surgery","Postoperative Recovery","Postoperative Pain","Length of Hospital Stay",[33,34,35,36,37,38],"Virtual Reality","VR Therapy","Distraction Therapy","ERAS (Enhanced Recovery After Surgery)","Perioperative Care","Non-pharmacological Pain Management","RECRUITING","2026-04-19",{"date":42,"type":43},"2026-04-23","ACTUAL",{"date":45,"type":43},"2026-03-28",{"date":47,"type":22},"2026-05",{"name":49,"class":50},"Alexandria University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":64,"conditions":65,"keywords":71,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":51},"100621011","the-primrose-trial-100621011","NCT07365072","The PRIMROSE Trial","A Randomised Controlled Trial to Evaluate the Impact of Thoracic PRehabilitation With Inspiratory Muscle tRaining cOmpared to Standard prEhabilitation in People With Lung Cancer for Surgical Treatment . The PRIMROSE Trial","PRIMROSE","Inclusion Criteria: Adults with lung cancer with surgically resectable disease who are referred for pre-treatment optimization with Prehab, from the lung cancer Multi-Disciplinary Teams (MDTs).\n\nThe referral criteria for Prehab is below:\n\n* ≥1 Medical Research Council (MRC) dyspnoea score\n* ≥1 World Health Organization (WHO) performance status (PS)\n* Age ≥ 70 years\n* Frailty index \\>3\n* Borderline or poor pulmonary function (forced expiratory volume in one second (FEV1) \\\u003C 50% or diffusion capacity for carbon monoxide (DLCO) \\\u003C50%)\n* Sedentary people despite having adequate FEV1 or DLCO\n* People who are eligible for surgical procedures, including endobronchial excision of tumour, or lobectomy, segmental resection, pneumonectomy or wedge resection, either via a minimally invasive approach or a standard thoracotomy approach\n\nAdditionally:\n\n* Participants will be included in the trial if they are capable of providing verbal and written consent for Prehab, and written consent for undergoing a surgical procedure for lung cancer\n* People over 18 years of age\n* All people will be considered regardless of their baseline respiratory muscle strength\n\nExclusion Criteria: Inclusion criteria not met\n\n* People diagnosed with other cancers namely, metastatic lung cancer, mesothelioma, sarcoma, mediastinal tumours, or benign diseases\n* People who decline Prehab\n* People who do not consent to Prehab, and do not attend Prehab. People who do not consent to surgery\n* People with a high cardiovascular risk for Prehab and awaiting investigations or interventions (including unstable angina and syncope)\n* People with a serious concomitant disorder that would compromise safety during Prehab\n* People with an abdominal hernia or recent abdominal surgery\n* People with a history of spontaneous pneumothorax and\u002For evidence of large bullae on radiological imaging\n* People with an inability to understand written and\u002For spoken English (only if carers are able to translate)\n* People with a perforated ear drum\n* People with worsening heart failure signs and symptoms after IMT\n* People with pulmonary hypertension\n* People who have suffered from or likely to suffer from costochondritis\n* If a participant was involved in a similar study, with potential to cause bias or conflict of interest then they will be excluded","90 Years",{"count":62,"type":22},100,[25],"Smoking is a major cause for developing lung cancer. People diagnosed with lung cancer, may be offered surgery which offers a complete cure. Smoking also damages the lungs and compromises a person's lung function, resulting in shortness of breath. Breathlessness limits the ability to carry out daily physical activities and exercise and makes people vulnerable to developing post procedure complications and even death. Some people with surgically treatable lung cancer have a poor ability to exercise and compromised lung function and are not fit for surgery. They will instead be referred for radiation therapy, chemotherapy or palliative care. Surgery is the preferred treatment option.\n\nThe pulmonary rehabilitation program (Prehab) improves fitness levels. In addition, it improves the level of breathlessness, exercise capacity and vulnerability of people with lung cancer, with the aim of making them fit for safe surgery. By adding a breathing training device to the Prehab program, the investigators aim to further improve participants fitness for surgery, lower their risk of developing complications and the time spent in hospital after the procedure. The breathing training device is called an inspiratory muscle training device. The hand-held device helps to train and strengthen the breathing muscles, which are then able to work more effectively. After the procedure, participants may be able to breathe and exercise more easily reducing their risk of developing complications and improving outcomes.\n\nThe study will compare two groups of people with lung cancer having surgical removal of part of the lung, at a specialist hospital . One group will receive standard Prehab and inspiratory muscle training with the device prior to the procedure; patients in the second group with receive standard Prehab prior to the procedure. Participants will be followed up for twelve months.",[66,67,68,69,70,31],"Cancer","Lung Resection","Inspiratory Muscle Training","Prehabilitation","Respiratory Complications",[72,66,73,69,74,75,76],"Inspiratory muscle training","Lung resection","Lung surgery","Randomised control trial","length of hospital stay","2026-01-28",{"date":79,"type":43},"2026-01-30",{"date":81,"type":43},"2025-05-01",{"date":83,"type":22},"2027-05-01",{"name":85,"class":50},"Swansea Bay University Health Board",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":96,"conditions":97,"keywords":102,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":51},"100618302","opioid-consumption-after-thoracotomy-and-factors-affecting-postoperative-acute-pain-100618302","NCT07329855","Opioid Consumption After Thoracotomy and Factors Affecting Postoperative Acute Pain","Analysis of Opioid Consumption After Thoracotomy and Factors Affecting Postoperative Acute Pain","Inclusion Criteria:\n\n* Patients aged over 18 years\n* Patients scheduled for thoracotomy\n* Patients with an American Society of Anesthesiologists (ASA) physical status classification of I-III\n* Patients who have provided informed consent\n* Patients with a body mass index (BMI) between 18-40 kg\u002Fm²\n\nExclusion Criteria:\n\n* Patients with ASA class IV or higher\n* Patients younger than 18 years old\n* Patients with systemic inflammatory disease\n* Patients receiving continuous anti-inflammatory and\u002For analgesic medication\n* Patients with chronic preoperative pain\n* Pregnant patients\n* Outpatients who received anesthesia outside the operating room\n* Emergency cases\n* Patients who underwent VATS, sternotomy, mediastinoscopy, or tracheal resection\n* Patients with a history of previous thoracic surgery\n* Patients who had a thoracic epidural catheter inserted for postoperative pain management\n* Patients with a BMI \\\u003C18 or \\>40 kg\u002Fm²",{"count":94,"type":22},35,"OBSERVATIONAL","Thoracic surgery operations constitute a significant portion of surgical procedures performed in hospitals. In the United States, more than 50,000 thoracic surgical procedures are performed annually, and more than 80% of these patients experience moderate to severe postoperative pain requiring opioid administration, which increases the risk of complications . It has also been reported that chronic pain develops in approximately 50% of patients after thoracic surgery .\n\nThoracic surgery is commonly associated with severe, multifactorial pain during the postoperative period and is among the surgical branches with a high risk of developing chronic pain Despite advances in understanding postoperative pain mechanisms and improvements in pain management, inadequate postoperative pain control remains an unresolved healthcare problem. Higher acute pain scores are associated with less effective ventilation and coughing, increased incidence of lower respiratory tract infections, and prolonged ICU and hospital stays .\n\nIn the management of acute postoperative pain after thoracic surgery, clinicians have sought alternatives to thoracic epidural analgesia to avoid its potential adverse effects. Truncal blocks such as thoracic paravertebral block, erector spinae plane block, and serratus anterior block have been used to reduce postoperative pain . Additionally, various other analgesic techniques such as patient-controlled analgesia (PCA) and multimodal analgesia have been employed. Historically, the cornerstone of acute postoperative pain control has been systemic opioids administered via oral, intravenous, or thoracic epidural routes . Although opioids provide excellent pain relief, they are associated with significant side effects that can adversely affect recovery .\n\nWith the increasing use of ultrasonography (USG), truncal blocks have become more widespread. Alongside the development of Enhanced Recovery After Thoracic Surgery (ERATS) protocols, efforts have been made to reduce opioid use, leading to differing opinions regarding the management of acute pain after thoracic surgery. To prevent opioid use disorder and potential side effects, opioid-free or opioid-sparing approaches are now being encouraged in perioperative pain management . Conversely, some studies suggest that intraoperative opioid administration may have favorable effects on postoperative acute and chronic pain. Previous research has reported that the average daily opioid consumption after thoracic surgery is approximately 30 morphine milligram equivalents (MME) .\n\nAlthough video-assisted thoracoscopic surgery (VATS) has become more common, thoracotomy cases still constitute a large proportion of thoracic surgery procedures. Moreover, severe postoperative pain after thoracic surgery is most commonly associated with the thoracotomy incision itself. While some studies have suggested that new truncal block techniques may provide effective analgesia and reduce opioid consumption after thoracotomy, further studies are needed to determine which blocks are most commonly preferred and how opioid consumption patterns have changed with the adoption of these newer regional techniques.\n\nA review of the current literature reveals that the factors influencing acute pain after thoracotomy have not been sufficiently evaluated. Therefore, a re-evaluation of the factors affecting acute pain following thoracotomy, considering recent developments in pain management, is necessary. Furthermore, examining the relationship between perioperative opioid consumption, postoperative complications, and hospital length of stay in this patient population will provide valuable contributions to the literature.\n\nThe aim of this study is to evaluate the amount of opioid consumption following thoracotomy and to investigate whether perioperative opioid use affects acute pain, postoperative complications, and the length of hospital stay.",[98,99,100,101,31],"Thoracic Anesthesia","Thoracotomy","Opioid","Postoperative Pain Management",[99,103,104,105,76],"opioid consumption","postoperative acute pain","postoperative complications","NOT_YET_RECRUITING","2026-01-09",{"date":109,"type":43},"2026-01-12",{"date":111,"type":22},"2026-01-05",{"date":113,"type":22},"2026-05-05",{"name":115,"class":116},"Ankara Ataturk Sanatorium Training and Research Hospital","OTHER_GOV",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":124,"minAge":18,"maxAge":19,"enrollmentInfo":125,"targetDuration":4,"studyType":23,"phases":127,"briefSummary":129,"conditions":130,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":51},"100436402","phase-4-preoperative-coadministration-of-low-concentration-carbohydrate-and-nitrates-loading-vs-low--concentration-carbohydrate-loading-alone-in-patients-undergoing-open-gynecological-surgeries-100436402","NCT04962776","Preoperative Coadministration of Low-concentration Carbohydrate and Nitrates Loading vs Low- Concentration Carbohydrate Loading Alone in Patients Undergoing Open Gynecological Surgeries","A Randomised Controlled Study of Preoperative Coadministration of Low-concentration Carbohydrate and Nitrates Loading vs Low- Concentration Carbohydrate Loading Alone in Patients Undergoing Open Gynecological Surgeries","Inclusion Criteria:\n\n* Patients ageing from 18 to 60 years,\n* American Society of Anesthesiologists (ASA) physical status I,II\n* scheduled for elective open gynecological surgeries\n\nExclusion Criteria:\n\nPatients with\n\n* Previous chemotherapy treatment,\n* Disseminated malignant disease,\n* BMI more than 40,\n* Known allergy to one or more of the study medications\n* Refusal to participate in the study\n* Patients diagnosed with diabetes milieus either type I or type II,\n* Patients with previous bariatric surgeries\n* Patients under medications that delay gastric emptying (tricyclic anti-depressants, chronic use of laxatives)","FEMALE",{"count":126,"type":22},90,[128],"PHASE4","Surgery is known to be associated with stress response affecting in a negative way the clinical outcome and patient experience. The stress response includes both sympathetic nervous system activation and systemic inflammatory response. The pituitary- sympathetic one leads to a number of metabolic changes as hyperglycemia, nitrogen loss and lipolysis on the other hand the systemic inflammatory response aggravates the perioperative metabolic changes. One of components of ERAS is preoperative carbohydrate load. Oral carbohydrate was associated with attenuation of the postoperative metabolic stress response. Nitrate rich drinks before exercises have a promising impact due to improving blood flow, mitochondrial efficiency, glucose uptake and the sarcoplasmic calcium handling all of which maximize resistance to fatigue and improved exercise performance.",[31],"2025-11-15",{"date":133,"type":43},"2025-11-19",{"date":135,"type":43},"2021-08-01",{"date":137,"type":22},"2026-04-30",{"name":139,"class":50},"Ain Shams University",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":147,"minAge":19,"maxAge":60,"enrollmentInfo":148,"targetDuration":4,"studyType":23,"phases":150,"briefSummary":151,"conditions":152,"keywords":156,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":51},"100483571","enhanced-recovery-after-surgery-eras-pathway-in-patients-undergoing-robot-assisted-laparoscopic-radical-prostatectomy-100483571","NCT05576766","Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy","Impact of Enhanced Recovery After Surgery (ERAS) Pathway on Outcomes in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 60 years or over but below 90 years.\n* Scheduled to undergo robot-assisted laparoscopic radical prostatectomy (RARP) for prostate cancer.\n* Agree to participate in this study and give written informed consent.\n\nExclusion Criteria:\n\n* Scheduled to undergo combined surgery, including RARP combined with pelvic lymph node dissection or other procedures.\n* American Society of Anesthesiologists (ASA) physical classification ≥IV.\n* Inability to receive preoperative aerobic exercise because of severe cardiovascular disease, motor system diseases (arthritis, lumbar vertebrae disease), or central nervous system diseases (epilepsy, parkinsonism).\n* Inability to communicate in the preoperative period because of profound dementia, deafness, or language barriers.\n* History of schizophrenia, anxiety or depressive disorders, or other mental disorders.","MALE",{"count":149,"type":22},54,[25],"Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer. How to improve recovery following RARP surgery is worth investigating. The enhanced recovery after surgery (ERAS) pathway involves a series of evidence-based procedures. It is aimed to reduce the systemic stress response to surgery and shorten the length of hospital stay. This randomized trial aims to investigate the impact of Enhanced Recovery After Surgery (ERAS) Pathway on early outcomes after RARP surgery.",[153,154,155,69,31],"Prostate Cancer","Robot-Assisted Laparoscopic Radical Prostatectomy","Enhanced Recovery After Surgery (ERAS) Protocol",[153,154,157,158,159,69,160],"RARP","Enhanced Recovery After Surgery","ERAS","Length of hospital stay","2025-08-15",{"date":163,"type":43},"2025-08-21",{"date":165,"type":22},"2025-09",{"date":167,"type":22},"2026-12",{"name":169,"class":50},"Peking University First Hospital",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":95,"phases":4,"briefSummary":179,"conditions":180,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":187,"leadSponsor":189,"locationsCount":51},"100592115","the-effect-of-perioperative-nutritional-care-on-recovery-after-knee-and-hip-replacement-surgery-100592115","NCT06989229","The Effect of Perioperative Nutritional Care on Recovery After Knee and Hip Replacement Surgery","Prospective Study on the Impact of Perioperative Nutritional Care in Patients Undergoing Total Knee and Hip Arthroplasty on Postoperative Outcomes","Inclusion Criteria:\n\nElective total hip replacement Elective total knee replacement\n\nExclusion Criteria:\n\nHip fracture Diabetes mellitus 1 Insulinotherapy",{"count":178,"type":22},1000,"This prospective observational study will assess the impact of standardized perioperative nutritional care on postoperative outcomes in patients undergoing elective total hip (THA) or knee arthroplasty (TKA) at the First Department of Orthopaedic Surgery, St. Anne's University Hospital in Brno. The protocol includes preoperative patient education, nutritional risk screening, and carbohydrate loading up to two hours before anesthesia, followed by early postoperative refeeding.\n\nData collection will include demographic and surgical variables, nutritional status, carbohydrate intake, and the occurrence of intra- and postoperative complications, including infection and delayed wound healing.\n\nAs perioperative nutritional care is part of routine clinical practice, the study requires no additional interventions or resources. Results will provide evidence on the effectiveness of structured nutritional support in enhancing recovery and reducing complications after joint replacement surgery.",[181,182,31],"Postoperative Outcomes","Postoperative Complications","2025-05-21",{"date":185,"type":43},"2025-05-25",{"date":81,"type":43},{"date":188,"type":22},"2027-12-31",{"name":190,"class":50},"St. Anne's University Hospital Brno, Czech Republic"]