[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lepidic-predominant-lung-adenocarcinoma\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lepidic-predominant-lung-adenocarcinoma":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100629778","low-glucosehigh-fat-intake-dietary-regimen-as-a-tool-for-empowering-diagnostic-accuracy-of-2-18ffdg-petct-in-lepidic-predominant-growth-lung-adenocarcinoma-100629778",false,"NCT07479095","Low-glucose\u002FHigh-fat Intake Dietary Regimen as a Tool for Empowering Diagnostic Accuracy of 2-[18F]FDG PET\u002FCT in Lepidic-predominant Growth Lung Adenocarcinoma","KETO-FDG Lung","Inclusion Criteria:\n\n* Written informed consent.\n* Age 18 years or older.\n* CT evidence of a lung nodule suspicious for LPA or lung biopsy positive for LPA.\n* Target nodule diameter at least 10 mm.\n* ECOG performance status 0 to 2.\n* Willingness and ability to adhere to a controlled ketogenic diet for 7 days.\n* Ability to comply with study procedures and visit schedule.\n\nExclusion Criteria:\n\n* Not suitable for prolonged imaging procedures.\n* Renal failure.\n* Type 1 diabetes mellitus.\n* Pancreatitis.\n* Severe dyslipidemia.\n* Other malignancies that are progressing or required active treatment within the previous 3 years.\n* Serious or unstable medical, psychiatric, or substance use disorders that could interfere with study participation.\n* Pregnancy or breastfeeding.\n* Refusal to participate","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study evaluates whether a 7-day ketogenic dietary regimen before 2-\\[18F\\]FDG PET\u002FCT can improve the diagnostic accuracy of imaging in adults with suspected or histologically confirmed lepidic-predominant lung adenocarcinoma (LPA). LPA frequently shows low glucose metabolism and may yield false-negative FDG PET\u002FCT results. Approximately 30 participants will undergo a tailored ketogenic diet for 7 days before PET\u002FCT. Imaging results will be compared with histopathology and additionally assessed against literature-reported diagnostic performance and a matched retrospective institutional cohort.",[26,27],"Lepidic-Predominant Lung Adenocarcinoma","Lung Adenocarcinoma",[29,30,31,32,33],"2-[18F]FDG PET\u002FCT","Ketogenic Diet","Lepidic Adenocarcinoma","Lung Nodule","Diagnostic Accuracy","RECRUITING","2026-03-18",{"date":37,"type":38},"2026-03-20","ACTUAL",{"date":40,"type":38},"2025-07-03",{"date":42,"type":20},"2027-03-30",{"name":44,"class":45},"Fondazione del Piemonte per l'Oncologia","OTHER"]