[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"levothyroxine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:levothyroxine":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100565855","thyroid-hormone-replacement-after-radio-iodine-value-and-efficacy-100565855",false,"NCT06647602","Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy","THRIVE","Inclusion Criteria:\n\n* Histologically confirmed DTC (papillary thyroid carcinoma, follicular thyroid carcinoma, oncocytic thyroid carcinoma)\n* Classified as high-risk DTC according to the ATA guidelines or, patients for whom the risk of a recurrence is estimated to be higher based on clinical features (assessed by their treating physician).\n* Prepared for RAI-therapy with TH-withdrawal\n* Patients must be fit to adhere to the study protocol\n* Patients must be able to read and understand the Dutch language\n\nExclusion Criteria:\n\n* Pregnancy\n* Patients with comorbidities, such as severe heart failure, (poorly controlled) atrial fibrillation, of which the treating physician decides that L-T3 is unsuitable.\n* Conditions or drugs interfering with thyroid hormone uptake:\n* Patients with a history of atrophic gastritis\n* Patients using proton-pomp inhibitors","ALL","18 Years","75 Years",{"count":20,"type":21},40,"ESTIMATED","OBSERVATIONAL","This study will be a multicentre prospective cohort study on TH-substitution after thyroid hormone withdrawal preceding radioiodine treatment.",[25,26,27,28,29],"Differentiated Thyroid Cancer","Thyroid Cancer","Levothyroxine","Liothyronine","Thyroid Hormones","NOT_YET_RECRUITING","2026-02-05",{"date":33,"type":34},"2026-02-10","ACTUAL",{"date":36,"type":21},"2026-09-01",{"date":38,"type":21},"2028-12-31",{"name":40,"class":41},"University Medical Center Groningen","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100623171","levothyroxine-treatment-on-cardiac-function-in-children-with-subclinical-hypothyroidism-100623171","NCT07393165","Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism","The Effect of Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism","Inclusion Criteria:\n\n* Age from 4 to 15 years.\n* Both sexes.\n* Patients with stable elevated thyroid-stimulating hormone (TSH) ≥ 4.5 mIU\u002FL with normal free T4 and ft3 in different measurement 4 - 6 weeks apart.\n\nExclusion Criteria:\n\n* Overweight and obesity\n* Hypertension\n* Previous use of levothyroxine, antiepileptic drugs, or cardiac drugs within the last 6 months.\n* Arrhythmia.\n* Congenital or acquired heart disease\n* Liver or kidney disease\n* Hyperlipidemia\n* Diabetes\n* Infectious diseases\n* Respiratory diseases\n* Malignancies","4 Years","15 Years",{"count":20,"type":21},"INTERVENTIONAL",[54],"NA","This study aims to evaluate the effect of the treatment with levothyroxine on cardiac function in children with subclinical hypothyroidism.",[27,57,58,59],"Cardiac Function","Children","Subclinical Hypothyroidism","RECRUITING","2026-01-31",{"date":63,"type":34},"2026-02-06",{"date":65,"type":34},"2025-05-24",{"date":67,"type":21},"2026-05-01",{"name":69,"class":41},"Tanta University",1]