[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"libido-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:libido-disorder":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100624346","transdermal-testosterone-gel-for-female-sexual-interest-and-arousal-disorder-in-peri--and-post-menopause-100624346",false,"NCT07408440","Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause","Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause - A Randomized, Double-blind, Placebo-controlled Trial for Improving Sexual Interest and Desire","TESTA MIND","Inclusion Criteria\n\n* Women 40-65 years; peri- or postmenopausal - with one of the following:\n\n  * Staging by STRAW+10: stage (-2) or above\n  * amenorrhea ≥12 mo\n  * Follicle stimulating hormone in menopausal range\n* FSIAD diagnosis according to the DSM-5: (3\u002F5 of the following symptoms)\n\n  * reduced or no interest in sex\n  * few or no thoughts about sex\n  * decreased sexual arousal or pleasure during sexual activity\n  * reduced or no arousal in response to visual, written, or verbal cues\n  * infrequent or no initiation of sexual activity within a relationship\n  * reduced or no sensations in the genitals\n\nThey must also have:\n\n* symptoms lasting 6 months or more\n* significant distress about their symptoms\n* symptoms that are not more accurately explained by a nonsexual mental health disorder, domestic abuse, medication, substance abuse, or another medical condition\n\n  * In a stable relationship or sexually active opportunity (as defined by participant)\n  * If on systemic estrogen ± progestin or local vaginal estrogen: stable dose ≥8 weeks before randomization and agrees to remain stable\n  * Able to consent and comply with study procedures\n\nExclusion Criteria\n\n* Current or recent (≤8 weeks) androgen therapy, dehydroepiandrosterone (DHEA), or anabolic steroids\n* Total T above premenopausal upper physiologic range at baseline (\\>55 ng\u002FdL)\n* History of hormone-dependent malignancy, untreated endometrial hyperplasia, or active gynecologic malignancy\n* Active severe psychiatric disorder (e.g., untreated major depression), substance use disorder, or relationship violence that precludes attribution of effect\n* Uncontrolled thyroid disease, significant liver disease, increased liver enzymes, or high cardiovascular risk judged unsafe by the primary care provider\n* Pregnancy, attempting conception, or breastfeeding\n* Dermatologic conditions preventing transdermal use; known hypersensitivity to the gel components",true,"FEMALE","40 Years","65 Years",{"count":22,"type":23},150,"ESTIMATED","INTERVENTIONAL",[26],"NA","Hypoactive sexual desire disorder (HSDD) is described as the most common form of female sexual dysfunction, particularly affecting peri- and postmenopausal women and is associated with significant distress and reduced quality of life. The TESTA-MIND study will evaluate the efficacy and safety of a standardized compounded transdermal testosterone gel in a randomized, double-blind, placebo-controlled design to address the lack of FDA-approved options and limited high-quality evidence for treating decreased libido in women.",[29,30,31,32],"Menopause","Sexual Dysfunction","Libido Disorder","Testosterone Deficiency","NOT_YET_RECRUITING","2026-02-12",{"date":36,"type":37},"2026-02-17","ACTUAL",{"date":39,"type":23},"2026-04-01",{"date":41,"type":23},"2028-03-30",{"name":43,"class":44},"The University of Texas Health Science Center, Houston","OTHER"]