[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lichen-sclerosus-lesion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lichen-sclerosus-lesion":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100545987","laser-treatment-for-lichen-sclerosus-100545987",false,"NCT06389071","Laser Treatment for Lichen Sclerosus","Safety and Efficacy of Ablative Fractional 2940 nm Laser Treatment for Lichen Sclerosus Lesion","Inclusion Criteria:\n\n* Female aged 18 years or older\n* Biopsy-proven vulvar lichen sclerosus lesion\n* Experiencing one or more of the following symptoms of LS:\n\n  1. Dryness\n  2. Itching\n  3. Burning\n  4. Bleeding\n  5. Blistering\n  6. Soreness\n  7. Easily bruises\n  8. Easily tears\n  9. Ulcerated lesions\n  10. Painful intercourse\n* Negative urine pregnancy test if subject is of childbearing potential before enrollment\n* Absence of vulvovaginal infection i.e. fungi, bacterial vaginosis, and STI\n* Ability to understand and sign informed consent, questionnaires, and all investigation requirements\n* Willing to consent to clinical photographs of the treatment area\n* Willing to consent to ultrasound images of the treatment area\n* Willing and able to logistically follow schedule of treatments and follow-up visits\n\nExclusion Criteria:\n\n* Pregnancy, less than 3 months postpartum, or planning to become pregnant during the investigation to protect integrity of the data\n* Is a nursing mother\n* History of uncontrolled malignant disease\n* Active urogenital infection or chronic infection (i.e., candida, herpes, herpes simplex, bacterial vaginosis, trichomoniasis, or other infection)\n* Immunocompromised (e.g., lymphoma, AIDS, Wiskott-Aldrich syndrome)\n* Subjects with genital skin disease, psoriasis due to risk of koeberizing\n* Subjects on immunosuppressants: mycophenolate, retinoids, azathioprine, cyclosporin\n* Known allergy or intolerance to local anesthesia\n* Known history of connective tissue disease\n* Known propensity for keloid formations\n* Known medical condition that may affect wound healing\n* Any reason that the investigator deems prohibits participation in the investigation",true,"FEMALE","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","Fractional ablative laser treatment for Lichen Sclerosus lesion",[27],"Lichen Sclerosus Lesion","RECRUITING","2026-04-21",{"date":31,"type":32},"2026-04-23","ACTUAL",{"date":34,"type":32},"2024-03-01",{"date":36,"type":21},"2027-12-30",{"name":38,"class":39},"Sciton","INDUSTRY"]