[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lifestyle-healthy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lifestyle-healthy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,60,93,130,158,190],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":40,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100644951","the-impact-of-enhanced-music--natural-visuals-on-emotional-health-100644951",false,"NCT07676110","The Impact of Enhanced Music & Natural Visuals on Emotional Health","Impacts of Music, Audio Enhancements, Audio Guidance, and Visuals on Physical and Emotional Well-being. (Emotional Health - Longitudinal 1 Randomized, Controlled Multi-center Study)","Inclusion Criteria:\n\n* You are 13 years of age or older\n* You can read, write, and speak English at a 5th-grade level or higher\n* You are legally capable of providing informed consent (adult participants) or capable of providing assent (child participants)\n* To the best of your knowledge, you are willing and able to commit to the session(s) and activities of this study\n* You are willing and able to use the sound-delivery and data-collection apparatus of this study\n* You are willing to use your own personal equipment. Depending on the study, you may need to have your own ear buds\u002Fheadphones and\u002For a \"smart\" device with internet and\u002For Bluetooth access (e.g., smartphone, iPad).\n* You have normal hearing in both ears.\n* You never experience ringing noises or buzzing sensations in your ears (tinnitus)\n* You do not use a heart\u002Fcardiac pacemaker and do not have any history of cardiac rhythm disturbances, such as cardiac conduction delays or blocks\n* You have no known history of fainting, fainting, spells or seizures, spinning sensations, or trouble with balance (medical terms include epilepsy, seizures, syncope, vertigo, nystagmus)\n* You do not use of any of the following medications: Beta blockers, steroids, ephedrine, acute anti-anxiety medication (e.g., benzodiazepines such as diazepam\u002FValium, lorazepam\u002FAtivan or clonazepam\u002FKlonopin), or acute or chronic pain medications (including narcotics and codeine)\n* For any study session, you will not be under the influence of any substances that could prevent safe participation and will not have consumed e.g., alcohol, THC, Psilocybin, or other mood-altering drugs in the 12 hours preceding the session.\n\nExclusion Criteria:\n\n\\-",true,"ALL","13 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress. Behavioral interventions-such as meditation, listening to music, or visualizing art or nature-offer important alternatives and\u002For adjunctive strategies to pharmaceutical tools or other mechanisms supporting physical and emotional well-being. This research will expand on the knowledge base regarding the impact of biophysical stimulation and\u002For frame of mind on an individual's self-directed management of physical and emotional health. Motivation, confidence, and composure are critical aspects of self-efficacy, framing a person's mindset to make healthy choices across daily activities.\n\nThe research in this protocol is carried out across multiple sites and studies by means of digital tools and a consistent participant experience workflow. Together, these resources are intended to support individuals across multiple self-directed experiences utilized in the maintenance of their basic health. Before, during, and after session experiences, the participant provides objective (physiological) responses and\u002For subjective (self-report) responses and reflections; some studies also include interviews or focus groups. The combined set of responses can be summarized, connected to other measures, and input to machine learning models to improve personalization of stimuli. By studying the effects of soundBrilliance experiences across a variety of contexts and participant samples, the investigators can better refine each element of the stimulus to improve satisfaction, tolerance, and targeted outcomes.",[27,28,29,30,31,32,33,34,35,36,37,38,39],"Emotion Management Skills","Lifestyle, Healthy","Lifestyle Intervention","Recovery","Exercise and Recovery","Exercise Training","Anxiety and Mood Disorders","Sleep","Motivation","Comfort","Pain Management","Rehabilitation","Creativity and Mindfulness",[41,42,43,44,45,46],"Music","Visuals","Visual Imagery","Biophysical Stimuli","Emotional Health","Emotional Management","RECRUITING","2026-06-23",{"date":50,"type":51},"2026-06-30","ACTUAL",{"date":53,"type":51},"2026-05-25",{"date":55,"type":21},"2027-06",{"name":57,"class":58},"soundBrilliance LLC","INDUSTRY",3,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":16,"sex":68,"minAge":69,"maxAge":4,"enrollmentInfo":70,"targetDuration":4,"studyType":22,"phases":72,"briefSummary":73,"conditions":74,"keywords":80,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":92},"100525008","strategies-for-implementing-a-postpartum-lifestyle-intervention-in-wic-clinics-100525008","NCT06116149","Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics","Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics: A Cluster Randomized Trial","STRIVE","Inclusion Criteria for Clinics:\n\n* Serve a large number of WIC postpartum participants\n* Willing and able to provide space for the study\n\nInclusion Criteria for Participants:\n\n* Age 18 or older\n* Gave birth in the past 6 weeks to 12 months\n* Obesity or history of gestational diabetes mellitus (Current BMI ≥30 kg\u002Fm², OR Medical-record documented history of gestational diabetes mellitus and BMI ≥25 kg\u002Fm²)\n* No self-reported diabetes (other than gestational diabetes)\n* Hemoglobin A1c \\\u003C6.5%\n* Not currently pregnant or planning to become pregnant in the next 6 months\n* No plans to move outside of the study region in the next 12 months\n* Access to a smartphone\n* Willing and able to participate in the intervention and provide consent\n* Not an immediate family member of the staff at the WIC clinic\n* Other concerns regarding ability to meet trial requirements, at the discretion of the principal investigator or study coordinator","FEMALE","18 Years",{"count":71,"type":21},722,[24],"The primary objective of the STRIVE study is to compare two implementation strategies for Diabetes Prevention Program delivery: an in-person health coach strategy (standard 24 in-person sessions at WIC clinics) vs. a multifaceted technology-assisted health coach implementation strategy (12 in-person sessions at WIC clinics supplemented by technology support) on implementation and health-related outcomes in postpartum women.",[75,76,28,77,78,79],"Obesity","Gestational Diabetes","Glucose Intolerance During Pregnancy","PreDiabetes","Hyperglycemia",[81],"Diabetes Prevention Program","2025-07-22",{"date":84,"type":51},"2025-07-25",{"date":86,"type":51},"2023-12-12",{"date":88,"type":21},"2027-04",{"name":90,"class":91},"Tulane University","OTHER",1,{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":16,"sex":17,"minAge":69,"maxAge":101,"enrollmentInfo":102,"targetDuration":4,"studyType":22,"phases":104,"briefSummary":105,"conditions":106,"keywords":110,"overallStatus":120,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":92},"100593709","an-exploratory-feasibility-study-100593709","NCT07009964","An Exploratory Feasibility Study","AI-Enhanced Educational Intervention to Support Contextual Well-being in Young Adults (ContextWell)","Contextwell","Inclusion Criteria:\n\nPrimarily healthcare students, young adults enrolled in higher education (18-30 years old)\n\nAccess to a computer or mobile device with an internet connection;\n\nWillingness to participate in the educational webinar;\n\nWillingness to complete AI-driven assignments;\n\nAble to read and understand English.\n\nExclusion Criteria:\n\nAre under the age of 18, or above 30;\n\nInability to access a computer or mobile device with internet connection;\n\nInability to read or understand English;\n\nUnwillingness to participate in the webinar or complete assignments.","30 Years",{"count":103,"type":21},12,[24],"This study explores the feasibility of ContextWell, a well-being education programme that combines an online webinar with an AI-powered behavioural nudging system. The programme aims to support university students, particularly those in healthcare disciplines, in enhancing well-being and adopting healthier lifestyle habits.\n\nThe primary objective is to determine whether the programme can be feasibly delivered within university settings. A secondary objective is to assess its potential to improve student well-being and encourage behavioural changes aligned with lifestyle medicine principles.\n\nThe intervention builds on the understanding that healthcare professionals' lifestyle habits and well-being have a direct impact on patient care. Focusing on healthcare students helps advance the integration of lifestyle medicine within health education and clinical practice.\n\nThis single-group feasibility study delivers the full intervention to all participants. Students participate in an online well-being webinar and receive AI-generated behavioural prompts designed to promote self-awareness and healthier daily choices.\n\nKey evaluation measures will indicated the feasibility of the programme among young adults in academic environments. Participant feedback and initial outcomes will support future development and inform larger-scale research.",[107,28,108,109],"Well-Being","Young Adult","Behavior and Behavior Mechanisms",[111,112,113,114,115,116,117,118,119],"Student well-being","Artificial Intelligence","Contextual Well-being","Contextual AI","Preventive health","Digital Health","Lifestyle medicine","Pilot study","Proof of concept","NOT_YET_RECRUITING","2025-06-18",{"date":123,"type":51},"2025-06-19",{"date":125,"type":21},"2025-11-01",{"date":127,"type":21},"2026-02-01",{"name":129,"class":91},"University College Dublin",{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":17,"minAge":69,"maxAge":4,"enrollmentInfo":138,"targetDuration":140,"studyType":141,"phases":4,"briefSummary":142,"conditions":143,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":92},"100532906","association-of-psychological-distress-in-patients-with-lung-cancer-100532906","NCT06218901","Association of Psychological Distress in Patients With Lung Cancer","the Association of Psychological Distress in Patients With Advanced Lung Cancer Treated With Immunotherapy or Targeted Therapy","Life-Score","Inclusion Criteria:\n\n* Histologically proven diagnosis of lung cancer\n* 18 years of age or older\n* Ability to understand and the willingness to sign a written informed consent document\n\nExclusion Criteria:\n\n* Not willing to participate in this clinical trial",{"count":139,"type":21},500,"3 Months","OBSERVATIONAL","Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and\u002For physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment. Psychological distress is common and affects the efficacy and prognosis of patients with lung cancer. The systematic anti-tumor therapy may effectively relieve psychological distress including anxiety, depression, and fatigue in patients with advanced lung cancer, the relief of the psychological distress can in turn improve the therapeutic effect.\n\nIn summary, this study is to explore the associations of (dynamic) psychological stress with the efficacy and survival of anti-tumor therapy including immunotherapy and targeted therapy for advanced lung cancer patients.",[144,145,146,28,147,148],"Lung Neoplasms","Psychological Distress","Prognosis Factors","IMMUNOTHERAPY","Targeted Molecular Therapy","2025-05-20",{"date":151,"type":51},"2025-05-22",{"date":153,"type":51},"2016-01-01",{"date":155,"type":21},"2028-12-31",{"name":157,"class":91},"Shanghai Chest Hospital",{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":11,"sex":17,"minAge":69,"maxAge":4,"enrollmentInfo":166,"targetDuration":4,"studyType":22,"phases":168,"briefSummary":169,"conditions":170,"keywords":172,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":92},"100456843","addressing-diabetes-by-elevating-access-to-nutrition-100456843","NCT05228860","Addressing Diabetes by Elevating Access to Nutrition","Addressing Diabetes by Elevating Access to Nutrition: the ADELANTE Study","ADELANTE","Inclusion Criteria:\n\n* For main study (index\u002Fintervention) participants:\n\n  * Age at enrollment: 18+ years\n  * Self-identified ethnicity: Hispanic, Latino, Chicano, or Spanish\n  * Type 2 diabetes indicated in the electronic health record, e.g. as ICD-10 (International Classification of Diseases) diagnosis code or HbA1c value\n  * Have indicated food insecurity according to the screening 2-item Hunger Vital Sign questionnaire\n  * Have a Body Mass Index (BMI) =\\> 25\n  * Receiving care at our partnering community health centers (e.g., Clinica de la Raza)\n  * Currently residing in Alameda or Contra Costa County and not expecting to relocate in the next 6-12 months\n  * Have access to phone or computer, email, and some internet for access to remote intervention and completion of follow-up measures\n* For household members:\n\n  * Age at enrollment: 12+ years\n  * Significantly involved in supporting nutrition in the home including food shopping, preparation, social support for healthy nutrition\n  * Willing to complete some questionnaires and attend a single group session.\n* For all participants:\n\n  * Able and willing to provide informed consent\n\nExclusion Criteria:\n\n* Unable to provide informed consent\n* Unable to speak, read, or understand English and\u002For Spanish\n* Active substance use or psychotic disorders that would impair participation in a group lifestyle intervention or interfere with follow-up assessments\n* Lacking mailing address for delivery of food box\n* Planning to relocate out of area within the next 12 months\n* Index participant only: Pregnant or planning to become pregnant within the next 12 months",{"count":167,"type":21},360,[24],"The goal of ADELANTE is to determine whether a multi-level intervention to improve household food insecurity and glycemic control is effective for Latino patients with diabetes.\n\nSpecifically, ADELANTE aims to\n\n1. determine whether weekly household food delivery plus an intensive lifestyle intervention is more effective than usual care for improving glycemic control (HbA1c) at 6 months,\n2. examine the effects of the multi-level intervention on = household food insecurity, dietary behaviors, and psychosocial outcomes, and\n3. assess the future potential for implementation and dissemination of this multi-level intervention in primary care settings.",[171,75,28],"Diabetes",[173,174,175,176,177,178,179,180],"food insecurity","community health worker","health coach","weight loss","HbA1c","T2DM","glycemic control","multilevel","2024-11-27",{"date":183,"type":51},"2024-12-02",{"date":185,"type":51},"2023-09-18",{"date":187,"type":21},"2027-09",{"name":189,"class":91},"Stanford University",{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":196,"eligibilityCriteria":197,"healthyVolunteers":16,"sex":68,"minAge":69,"maxAge":4,"enrollmentInfo":198,"targetDuration":4,"studyType":22,"phases":200,"briefSummary":201,"conditions":202,"keywords":207,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":92},"100530507","a-nutrition-and-exercise-lifestyle-intervention-program-participant-choice-approach-100530507","NCT06187675","A Nutrition and Exercise Lifestyle Intervention Program Participant Choice Approach","A Participant Choice Approach to Improve Adherence and Investigate Pregnancy Outcomes to Lifestyle Interventions","NELIP","Inclusion Criteria:\n\n* between 12 to 18 weeks of pregnancy\n* a singleton fetus\n* medically screened with the Get Active Questionnaire for Pregnancy to determine eligibility for participation in the exercise component\n\nExclusion Criteria:\n\n* inability to walk\n* serious medical problems\n* high blood pressure\n* uncontrolled chest pain\n* uncontrolled symptomatic lung disease\n* diabetes before pregnancy\n* a history of recreational substance use disorder\n* any contraindication to exercise\n* enrolled in another clinical trial.",{"count":199,"type":21},120,[24],"Interventions that target excessive gestational weight gain (EGWG) with nutrition and exercise behavior change struggle with low program adherence. The investigators recently examined adherence in a randomized controlled trial to a previously established lifestyle program called the Nutrition and Exercise Lifestyle Intervention Program (NELIP) and found that those individuals with high adherence to the program were more likely to prevent EGWG. Perhaps offering participants a choice to intervention strategies may improve adherence. The current research question is: What impact does participant choice have on adherence to the introduction of nutrition and exercise components during 3 intervention strategies offered to pregnant individuals compared to no choice and does choice maintain pregnancy health outcomes? The strategies are: Group A - introducing both the nutrition and exercise components simultaneous at baseline (12-18 weeks of pregnancy) that is followed to delivery (NELIP); Group B - introducing the nutrition component first and then at 25 weeks adding the exercise component; or Group C - starting with the exercise component first, followed with introducing the nutrition component at 25 weeks. Both Groups B and C follow the full NELIP from 25 weeks to delivery (final intervention measures will occur at 34-36 weeks gestation). Follow-up will occur at birth (6-18 hours), 2, 6 and 12 months post delivery.",[28,203,204,205,206],"Pregnancy Related","Adherence, Treatment","Nutrition, Healthy","Weight Gain, Maternal",[208,209,210,211,212],"pregnancy","lifestyle","nutrition","exercise","adherence","2024-03-01",{"date":215,"type":51},"2024-03-05",{"date":217,"type":51},"2024-01-01",{"date":219,"type":21},"2029-11",{"name":221,"class":91},"Western University, Canada"]