[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lifestyle-risk-reduction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lifestyle-risk-reduction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,47,73,100,136,166,196,224],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100627081","evidence-based-intervention-for-diabetes-prevention-100627081",false,"NCT07443995","Evidence-based Intervention for Diabetes Prevention","EID","Inclusion Criteria:\n\n* Men and women 18 years or older\n* Diabetes risk score \\> 5\n* BMI \\>=25kg\u002Fm\\^2\n* Arabic or English speaking\n* Able to read and write in Arabic or English\n* Access to a smartphone\n* Provide informed consent\n\nExclusion Criteria:\n\n* Prevalent diabetes\n* Prior participation in a diabetes prevention program\n* Taking FDA-approved weight loss medications\n* Pregnant or lactating","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this behavioral intervention trial is to develop strategies to decrease the incidence of diabetes within the UAE. The investigators will investigate the effectiveness of a group-based telehealth intervention facilitated by a health coach in adults at risk for developing diabetes who live in the UAE.\n\nThe investigators will conduct a single-arm feasibility trial of the Evidence-based Intervention for Diabetes prevention among thirty adults with prediabetes. All participants will receive 12 weekly virtual intervention sessions over the course of three months, facilitated by a trained DPP lifestyle coach who is from the same cultural community and can deliver the material in either Arabic or English.\n\nThe primary feasibility measure is acceptability, as measured by intervention session attendance. Other outcome assessments will be conducted at baseline and three months at NYU Abu Dhabi, where study staff will assess weight, hemoglobin A1c, diet, and physical activity.",[26,27,28],"Pre-diabetes","Lifestyle Risk Reduction","Diet Prevention of Metabolic Diseases",[30,31,32,33],"pre-diabetes","behavioral intervention","diet","physical activity","NOT_YET_RECRUITING","2026-02-24",{"date":37,"type":38},"2026-03-02","ACTUAL",{"date":40,"type":20},"2026-04",{"date":42,"type":20},"2027-08",{"name":44,"class":45},"New York University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":21,"phases":59,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100535969","food-literacy-intervention---is-a-train-the-trainer-approach-feasible-and-effective-100535969","NCT06258733","Food Literacy Intervention - is a \"Train the Trainer\" Approach Feasible and Effective?","Food Literacy Intervention for Arab and Jewish Women in the Jerusalem Region - is a \"Train the Trainer\" Approach Feasible and Effective?","Inclusion Criteria:\n\n* Hebrew or Arabic literate women who are over 25 years old\n\nExclusion Criteria:\n\n* Women who do not meet inclusion criteria.",true,"FEMALE","25 Years",{"count":58,"type":20},480,[23],"Food literacy (FL) is the capability to make healthy food choices in different contexts, settings and situations. Although eating habits are shaped by different circumstances and skills, most nutrition programs focus on nutrition knowledge alone. Addressing factors such as competencies, self-efficacy and social norms enables sustainable positive change in nutrition behaviour. This study will assess a lay leader-led FL workshop to Arab and Jewish women from disadvantaged communities in the Jerusalem region, utilizing a train-the-trainer approach, and will compare the effectiveness and cost-effectiveness of a lay-led FL intervention to an expert-led intervention.",[27,62,63],"Health Behavior","Food Habits","2025-12-16",{"date":66,"type":38},"2025-12-17",{"date":68,"type":20},"2025-12",{"date":70,"type":20},"2027-02-01",{"name":72,"class":45},"Hadassah Medical Organization",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":54,"sex":16,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":99},"100520159","health-without-barrierssalud-sin-barreras-100520159","NCT06052943","Health Without Barriers\u002FSalud Sin Barreras","Family-Inclusive Lifestyle Intervention for Teenagers in Rural Colorado","Inclusion Criteria:\n\nFamilies must have at least 1 teen that is between the ages of 11-19 years old and reside in La Plata, Montezuma, or Archuleta Counties.\n\nExclusion Criteria:\n\n* Participants will not take part in the program and\u002For research activities if they have a medical and\u002For psychological\u002Fbehavioral condition that, in the opinion of the Colorado State University\u002FExtension program team, could interfere with safety for themselves or others or interfere with the capability of the participant or other participants to potentially benefit from the program (e.g., severe emotional-behavioral disturbance, inability to follow facilitator directions) .\n* Parents\u002Fguardians will not take part in the program and\u002For research activities if they have a medical and\u002For psychological\u002Fbehavioral condition that, in the opinion of the Colorado State University\u002FExtension program team, could interfere with safety for themselves or others or interfere with the capability of their family or other participating families to potentially benefit from the program (e.g., using drugs or alcohol or under the use of drugs\u002Falcohol during program sessions, aggressive or inappropriate behavior toward other participants).","11 Years","19 Years",{"count":83,"type":20},175,[23],"The goal of this study is to address a key health inequity - lack of community access to evidence-based programs to prevent chronic health conditions (e.g., Type 2 Diabetes) - by tailoring and delivering a family-based lifestyle and stress management intervention, Health Without Barriers\u002FSalud Sin Barreras, for adolescents and their families living in rural Southwest Colorado. The intervention is a lifestyle program that addresses healthy lifestyle habits within the family context to support adolescent mental health (mindfulness intervention) and healthy weight (physical activity, nutrition, and parent education).",[87,88,27],"Mental Health Wellness","Family Research","RECRUITING","2025-11-12",{"date":92,"type":38},"2025-11-13",{"date":94,"type":38},"2022-09-21",{"date":96,"type":20},"2027-06",{"name":98,"class":45},"Colorado State University",2,{"id":101,"slug":4,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":54,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":21,"phases":109,"briefSummary":110,"conditions":111,"keywords":119,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":46},"100579291","NCT06822387","Health Without Barriers\u002FSalud Sin Barreras- Northern Colorado","Growing an Extension Network for Multisite Dissemination and Implementation of Intensive Health Behavior and Lifestyle Treatment","HWB\u002FSSB","Inclusion Criteria:\n\nAdolescent subjects\n\n* Between the ages 11-19 years old\n* Reside in Larimer County, Weld County, or the surrounding areas.\n\nParent\u002Fguardian subjects:\n\n* 18 years old or older\n* Are parents\u002Fguardians of an adolescent between the ages of 11-19\n* Reside in Larimer County, Weld County, or the surrounding areas\n\nFacilitators subjects\n\n* 18 years old or older\n* Reside in Larimer County, Weld County, or the surrounding areas\n* Are planning to or have facilitated HWB\n\nExclusion Criteria\n\nAdolescents subjects will not take part in the research activities if they have a medical and\u002For psychological\u002Fbehavioral condition that, in the opinion of the Colorado State University\u002FExtension program team, could interfere with safety for themselves or others or interfere with the capability of the participant or other participants to potentially benefit from the program (e.g., severe emotional-behavioral disturbance, inability to follow facilitator directions).\n\nParents\u002Fguardians will not take part in the research activities if they have a medical and\u002For psychological\u002Fbehavioral condition that, in the opinion of the Colorado State University\u002FExtension program team, could interfere with safety for themselves or others or interfere with the capability of their family or other participating families to potentially benefit from the program (e.g., using drugs or alcohol or under the use of drugs\u002Falcohol during program sessions, aggressive or inappropriate behavior toward other participants).\n\nThere is no exclusion for facilitator subjects.",{"count":108,"type":20},140,[23],"The overarching goal of this work is to address the limited access to evidence-based health behavior and lifestyle interventions for youth and families most impacted by preventable chronic diseases, including obesity and type 2 diabetes. In the current project, we implement a small single-arm pilot and feasibility trial of Health Without Barriers\u002FSalud Sin Barreras (HWB\u002FSSB), a culturally-adapted, whole-family intensive health behavior and lifestyle intervention to 11-19-year-old adolescents and their families living in Northern Colorado. Objectives are refining the HWB\u002FSSB community facilitator training, evaluating the feasibility and acceptability of HWB\u002FSSB implementation, and characterizing changes in health outcomes among adolescent participants.",[27,112,113,114,115,116,117,118],"Adolescent Health","Family Health","Cardio-metabolic Health","Mental Health","Wellness Program","Type 2 Diabetes","Obesity, Adolescent",[120,121,122,123,124,125,126,127],"Whole-family","Mindfulness","Wellness education","Nutrition","Physical Activity","Stress reduction","Health Without Barriers","Salud Sin Barreras","2025-04-29",{"date":130,"type":38},"2025-05-02",{"date":132,"type":38},"2025-04-07",{"date":134,"type":20},"2026-06-30",{"name":98,"class":45},{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":142,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":16,"minAge":144,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":21,"phases":147,"briefSummary":148,"conditions":149,"keywords":153,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":99},"100580089","lifestyle-intervention-in-the-memory-clinics-of-general-and-academic-hospitals-trial-100580089","NCT06832761","Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial","Secondary Prevention of Dementia in Memory Clinics: Implementation and (Cost-)Effectiveness of an Integrated Lifestyle Intervention","LIGHT","Inclusion Criteria:\n\n* ≥50 years of age at pre-screening;\n* Having a diagnosis of SCD or MCI;\n* Presence of ≥ 2 modifiable risk factors for dementia.\n\nExclusion Criteria:\n\n* Having a diagnosis of dementia;\n* Insufficient understanding of the Dutch language;\n* Conditions affecting safe and continuous engagement in the intervention (e.g. under treatment for current malignant diseases, major psychiatric disorders (e.g. major depression, psychosis, bipolar disorder), other conditions preventing co-operation as judged by the local study nurse or consulted physician at the local study site;\n* Participation in any other research intervention trial at time of pre-screening and throughout the study period.","50 Years",{"count":146,"type":20},300,[23],"Lifestyle Intervention in the memory clinics of General and academic Hospitals Trial (LIGHT) is a multi-center, randomized, controlled, lifestyle intervention trial among 300 older adults (≥50 years) with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) at risk of dementia. Participants are randomized in a 1:1 ratio to Group A (tailored lifestyle intervention) or Group B (general health advice) for a duration of 12 months. The lifestyle intervention comprises three parts 1) Lifestyle coaching, 2) a voucher program, and 3) online self-management. Group B will receive general health advice.",[150,27,151,152],"Lifestyle Intervention","Cognitive Decline","Dementia",[154,155,152,156],"Lifestyle intervention","Risk reduction","Memory clinic","2025-02-12",{"date":159,"type":38},"2025-02-18",{"date":161,"type":38},"2025-01-27",{"date":163,"type":20},"2027-12",{"name":165,"class":45},"Maastricht University Medical Center",{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":170,"acronym":171,"eligibilityCriteria":172,"healthyVolunteers":54,"sex":55,"minAge":173,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":21,"phases":177,"briefSummary":178,"conditions":179,"keywords":183,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":46},"100455170","healthy-early-life-moments-in-singapore-100455170","NCT05207059","Healthy Early Life Moments in Singapore","HELMS","Inclusion Criteria:\n\n1. Women aged 21-40 years\n2. BMI 25-40 kg\u002Fm2\n3. Intention to reside in Singapore for the next 4 years\n4. Chinese, Malay, Indian or any combination of these 3 ethnic groups\n5. Planning to conceive within 1 year\n6. Able to understand English\n7. Able to provide written, informed consent\n\nExclusion Criteria:\n\n1. Currently pregnant\n2. Known type 1 or type 2 diabetes\n3. On any anticonvulsant medication in the past 1 month\n4. On any oral steroid in the past 1 month (e.g. Prednisolone, Prednisone, Deltasone, Prelone, Methyl Prednisolone, Medrol, Hydrocortisone, Cortef, Dexamethasone, Decadron)\n5. On any oral, implanted contraception or intrauterine contraceptive device (IUCD) in situ in the past 1 month\n6. On any fertility medication (e.g. hormones injection, IVF treatments) other than Clomiphene\u002F Letrozole in the past 1 month\n7. On HIV or Hepatitis B or C medication in the past 1 month.","21 Years","40 Years",{"count":176,"type":20},500,[23],"This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health, among overweight and obese women.",[180,181,27,182],"Metabolic Disease","Mental Health Wellness 1","Maternal Obesity",[184,185,154],"Obesity","Mental health","2024-10-08",{"date":188,"type":38},"2024-10-10",{"date":190,"type":38},"2022-03-18",{"date":192,"type":20},"2028-12",{"name":194,"class":195},"KK Women's and Children's Hospital","OTHER_GOV",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":202,"eligibilityCriteria":203,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":204,"enrollmentInfo":205,"targetDuration":4,"studyType":21,"phases":207,"briefSummary":208,"conditions":209,"keywords":211,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":46},"100548734","effects-of-a-lifestyle-and-sleep-intervention-in-non-exercising-adults-100548734","NCT06424847","Effects of a Lifestyle and Sleep Intervention in Non-exercising Adults","Effects of a Lifestyle and Sleep Intervention Program on Quality of Life and Physical Activity Levels in Non-exercising Adults, SPIRAL+ Randomized Controlled Trial","SPIRAL+","Inclusion Criteria:\n\n* Participant who is physically inactive (i.e. less than 150 minutes of moderate intensity physical activity per week)\n* Participant aged 18 to 80 years old\n* Participant able to provide written informed consent\n* Participant able to participate in regular physical activity (no medical contraindication to exercise)\n* Participant affiliated to social security or a similar regimen\n\nExclusion Criteria:\n\n* Any condition that in the opinion of the responsible physician or investigator makes the potential participant unsuitable for the study\n* A participant who scores 11111 on the EQ-5D-5L questionnaire\n* A diagnosed and treated sleep disturbance (sleep apnea, insomnia, restless legs syndrome)\n* Persons concerned by articles L1121-5, L1121-6 and L1121-8 of the public health code (i.e. pregnancy, person deprived of liberty or subject to a legal protection measure, vulnerable person or legally protected adult)\n* Person already included in another interventional study","80 Years",{"count":206,"type":20},201,[23],"Background. Cardiovascular diseases (CVDs) are the leading cause of premature mortality and disability accounting for one third of all deaths worldwide with considerable impacts on economics and on quality of life. Recent studies suggest that a lifestyle intervention might have a role in the reduction of CDV risk. Lifestyle intervention programs typically combine physical activity, diet and behavior modification components. Poor sleep health is highly prevalent in the general population and contributes to increased risk of several noncommunicable diseases. However, sleep is rarely addressed in lifestyle intervention programs in primary prevention. Given the high prevalence of poor sleep health in people without a diagnosed sleep disorder, and the associated health consequences, there is a clear need for broad-reaching, effective interventions to improve sleep quality in subclinical populations.\n\nAims. The main objective of this study is to compare a lifestyle intervention program including a sleep intervention compared to a lifestyle intervention program alone on the health-related quality of life (measured by the EQ-5D-5L) and physical activity levels of non-exercising adults.\n\nMethods. Non-exercising adults (n=201) will be recruited in the community via advertisement or their primary care doctor and then randomized to one of the following 3 groups : lifestyle intervention, lifestyle and sleep intervention or standard care. The lifestyle intervention includes a physical activity component (physical activity initiation visit and 6 months of supervised physical activity, once weekly), a diet component (consultation with a dietician and 3 group sessions). The sleep intervention includes individualized face-to-face sessions aimed at improving and optimizing sleep hygiene.\n\nAt baseline and after 6 and 12 months, quality of life, physical activity levels, cardiovascular and metabolic risk factors will be evaluated.\n\nPerspectives. This study should determine whether adding a sleep intervention dimension to a lifestyle intervention program provides significant benefits in terms of quality of life and physical activity levels. Based on this study, the modalities of real-life lifestyle intervention programs could be reconsidered in order to provide optimal primary prevention.",[210,27],"Inactivity, Physical",[212,213,33,214],"lifestyle intervention","sleep intervention","behavior change techniques","2024-05-24",{"date":217,"type":38},"2024-05-28",{"date":219,"type":38},"2024-05-02",{"date":221,"type":20},"2028-05-01",{"name":223,"class":45},"University Hospital, Grenoble",{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":228,"acronym":229,"eligibilityCriteria":230,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":204,"enrollmentInfo":231,"targetDuration":4,"studyType":21,"phases":233,"briefSummary":234,"conditions":235,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":46},"100434115","patient-driven-lifestyle-modification-using-freestyle-libre-in-type-2-diabetes-patients-100434115","NCT04932928","Patient-Driven Lifestyle Modification Using FreeStyle Libre in Type 2 Diabetes Patients","PDF","Inclusion Criteria:\n\n* Age 19-80\n* Diagnosed with type 2 diabetes mellitus (DM)\n* Uncontrolled type 2 DM: HbA1c 7.0-10.0%\n* Signed informed consent\n\nExclusion Criteria:\n\n* Diagnosed with other types of diabetes mellitus (i.e. Type 1 DM)\n* Use of prandial insulin\n* Change in diabetes medication in the preceding 3 months\n* Pregnant\u002Flactating women\n* Addiction to drugs and alcohol\n* Use of medications that result in drug-induced hyperglycemia (i.e. steroid)\n* Severe liver disease\n* End-stage renal disease (i.e. on dialysis)\n* Unable to wear CGM devices due to dermatologic side effects (i.e. severe burn, inflammation, active skin infection, severe skin reactions, hypertrichosis, etc.)\n* Conditions that impact the stability of HbA1c measurement",{"count":232,"type":20},126,[23],"We aim to provide medical nutritional therapy to patients with type 2 diabetes who are on oral hypoglycemic agents or on basal insulin only and monitor the glycemic response with flash glucose monitoring or self-monitoring of blood glucose.\n\nSpecifically, this is a randomized, open-label, controlled study where half of the study participants will have FreeStyle Libre device on for 12 weeks and compare the change in glycated hemoglobin (HbA1c) value with the patients in the control group.",[236,27],"Diabetes Mellitus, Type 2","2021-06-13",{"date":239,"type":38},"2021-06-21",{"date":241,"type":38},"2021-03-23",{"date":243,"type":20},"2023-03-23",{"name":245,"class":45},"Seoul National University Hospital"]