[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lifestyle-sedentary-behavior-and-physical-activity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lifestyle-sedentary-behavior-and-physical-activity":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,83,115],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100608796","a-lifestyle-intervention-to-reduce-cardiometabolic-risk-factors-in-individuals-with-obsessive-compulsive-disorder-100608796",false,"NCT07206212","A Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder","Efficacy and Cost-effectiveness of a Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder: A Randomized Controlled Trial","LIFT","Inclusion criteria:\n\n1. A diagnosis of obsessive-compulsive disorder (OCD), based on the diagnostic criteria of the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders. Screened at registration and at the initial phone call and confirmed by the assessor at the inclusion assessment (psychiatric interview), using a semi-structured diagnostic interview.\n2. Physical inactivity\u002Fsedentarism, operationalized as less than 150 minutes of physical activity per week during the last month, evaluated by asking two questions from the Swedish National Board of Health and Welfare concerning 1) frequency of weekly moderate or vigorous intensity physical exercise and 2) frequency of weekly non-exercise\u002Fdaily life physical activity. Screened at registration and at the initial phone call and confirmed by the assessor at the inclusion assessment (psychiatric interview).\n3. Aged 18 years or older. Screened at registration and confirmed by the assessor at the initial phone call and\u002For confirmed by the assessor at the inclusion assessment (psychiatric interview).\n\nExclusion criteria:\n\n1. Intellectual disability or severe psychiatric symptoms or suicidal risk that could interfere with the intervention. Screened at the initial phone call and confirmed by the assessor at the inclusion assessment (psychiatric interview), using a semi-structured diagnostic interview.\n2. A diagnosis of an eating disorder or a substance use disorder. Screened at the initial phone call and confirmed by the assessor at the inclusion assessment (psychiatric interview), using a semi-structured diagnostic interview.\n3. Being pregnant or \\\u003C1 year postpartum. Screened at the initial phone call and confirmed by the assessor at the inclusion assessment (psychiatric interview).\n4. Myocardial infarction or stroke within the last 6 months. Screened at registration and confirmed by the assessor at the initial phone call and\u002For the inclusion assessment (physiological measures).\n5. Cardiovascular risk measures significantly over the normal range (e.g., severe hypertension \\[blood pressure above ≥180 mmHg systolic or ≥110 mmHg diastolic\\]) or a current somatic condition that make participation in the intervention contraindicated. Screened at registration and confirmed by the assessor at the initial phone call and\u002For the inclusion assessment (physiological measures), after consulting with the study doctor, if necessary.\n6. Initiation or adjustment of any cardiometabolic medication (e.g., blood pressure or blood lipids lowering mediation) within 3 months prior to assessments. Screened at registration and confirmed by the assessor at the initial phone call and\u002For the inclusion assessment (physiological measures).\n7. Inability to understand and communicate in Swedish. Confirmed by the assessor at the initial phone call.\n8. Inability to consistently attend the sessions involved in the intervention. Screened by the assessor at the initial phone call and\u002For confirmed by the assessor at the inclusion assessment (psychiatric interview).\n9. Inability to travel to the sessions involved in the intervention. Screened by the assessor at the initial phone call and\u002For confirmed by the assessor at the inclusion assessment (psychiatric interview).","ALL","18 Years",{"count":20,"type":21},108,"ESTIMATED","INTERVENTIONAL",[24],"NA","The overall aim of this study is to evaluate the efficacy and cost-effectiveness of a lifestyle intervention to improve lifestyle habits and reduce cardiometabolic risk factors in individuals with obsessive-compulsive disorder (OCD).",[27,28],"Obsessive Compulsive Disorder (OCD)","Lifestyle (Sedentary Behavior and Physical Activity)",[30,31,32,33,34,35,36],"OCD","Obsessive-compulsive disorder","Cardiovascular disease","Metabolic syndrome","Prevention","Lifestyle habits","Physical activity","RECRUITING","2026-05-13",{"date":40,"type":41},"2026-05-15","ACTUAL",{"date":43,"type":41},"2026-01-30",{"date":45,"type":21},"2028-11-01",{"name":47,"class":48},"Karolinska Institutet","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100634103","exercise-targeted-smart-lifestyle-management-100634103","NCT07535333","Exercise-Targeted Smart Lifestyle Management","Study on the Improvement Effects of Intelligent Lifestyle Management, Targeting Exercise Capacity Enhancement, on Overweight\u002FObesity With Metabolic Syndrome","Inclusion Criteria:\n\n* Aged between 20 and 60 years.\n* Overweight or obese, with a Body Mass Index (BMI) ≥ 24 kg\u002Fm² and \\\u003C 40 kg\u002Fm².\n* Patients with impaired metabolic parameters regarding glucose, lipids, and blood pressure，meet at least two of the following criteria:\n\n  * Central obesity: Waist circumference ≥ 90 cm for males or ≥ 85 cm for females.\n  * Hyperglycemia: Fasting plasma glucose (FPG) ≥ 6.1 mmol\u002FL, or 2-hour plasma glucose ≥ 7.8 mmol\u002FL during an oral glucose tolerance test (OGTT), and\u002For currently receiving treatment for previously diagnosed diabetes.\n  * Hypertension: Blood pressure ≥ 130\u002F85 mmHg, and\u002For currently receiving treatment for previously diagnosed hypertension.\n  * Elevated fasting triglycerides (TG): ≥ 1.7 mmol\u002FL.\n  * Reduced fasting high-density lipoprotein cholesterol (HDL-C): \\\u003C 1.04 mmol\u002FL.\n\nExclusion Criteria:\n\n* History of cardiovascular or cerebrovascular disease, or in the acute phase, including: angina pectoris, myocardial infarction, coronary revascularization surgery, stroke (ischemic or hemorrhagic, including transient ischemic attack), symptomatic peripheral artery disease requiring surgery or diagnosed via angiographic techniques, ventricular arrhythmias, uncontrolled atrial fibrillation, congestive heart failure (New York Heart Association class III or IV), hypertrophic cardiomyopathy, history of aneurysm with diameter ≥ 5.5 cm, or history of aneurysm surgery.\n* Malignancy or history of malignancy within the past five years.\n* Religious restrictions or dysphagia preventing adherence to the recommended diet.\n* Contraindications to exercise, such as orthopedic disorders.\n* Participation in other weight-loss programs (\\> 5 kg weight loss) within the six months prior to the screening visit.\n* History of bariatric surgery or intention to undergo bariatric surgery within the next 12 months.\n* History of small or large bowel resection or inflammatory bowel disease.\n* Obesity due to endocrine disorders of unknown cause (excluding treated hypothyroidism).\n* Allergy to any food components of the Mediterranean diet.\n* Immunodeficiency or HIV positive status.\n* Cirrhosis or liver failure.\n* Severe psychiatric disorders, including schizophrenia, bipolar disorder, eating disorders, or depression requiring hospitalization in the past 6 months.\n\nSevere comorbidities with a life expectancy of less than 24 months.\n\n* Alcoholism, addiction, or drug abuse in the past six months (or daily alcohol consumption \\> 50 g).\n* History of major organ transplantation.\n* Concomitant use of immunosuppressive or cytotoxic medications.\n* Current use of systemic corticosteroids.\n* Current use of weight-loss medications.\n* Currently participating in another randomized clinical trial.\n* Patients with acute infection or inflammation (e.g., pneumonia) may -participate 3 months after resolution of the condition.\n* Pregnant or planning to become pregnant during the study period.\n* Any other condition that may interfere with protocol compliance.\n* Refusal to sign the informed consent document.","20 Years","60 Years",{"count":60,"type":21},435,[24],"To investigate the effects of simple dietary management and diet combined with exercise capacity-targeted intelligent lifestyle management on improving metabolic indicators in patients with overweight\u002Fobesity and metabolic syndrome.",[64,65,66,28,67],"M-health","Metabolic Syndrome","Lifestyle Alteration","Overweight , Obesity",[69,65,70,71,67],"mhealth","Lifestyle (sedentary behavior and physical activity)","Mediterranean Diet","NOT_YET_RECRUITING","2026-04-09",{"date":75,"type":41},"2026-04-17",{"date":77,"type":21},"2026-05",{"date":79,"type":21},"2027-06",{"name":81,"class":82},"China National Center for Cardiovascular Diseases","OTHER_GOV",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":49},"100633227","maff-crt-reducing-sedentary-behaviour-in-children-100633227","NCT07523945","MAFF-CRT: Reducing Sedentary Behaviour in Children","MAFF-CRT: School-to-Home Trial to Reduce Sedentary Behaviour in Children","MAFF-CRT","Inclusion Criteria:\n\n* Enrolled in participating Portuguese public schools\n* Written informed consent provided by a parent or legal guardian\n* Assent provided by the child\n* Able to participate in light-to-moderate physical activity as part of normal school activities\n\nExclusion Criteria:\n\n* Medical conditions or physical limitations that contraindicate participation in physical activity\n* Cognitive, developmental, or behavioural conditions that would prevent understanding or adherence to the intervention procedures (as assessed by school staff)\n* Lack of parental\u002Flegal guardian consent\n* Concurrent participation in another structured physical activity or behavioural intervention study",true,{"count":93,"type":21},200,[24],"Children today spend many hours sitting at school and at home, often in front of screens. Prolonged sitting in childhood increases the risk of future health problems such as diabetes, heart disease and poor mental wellbeing. MAFF is a simple school-to-home programme that teaches short, practical movement breaks in the classroom and encourages families to repeat them together at home through structured weekly challenges. Over 12 weeks, we will compare classes using MAFF with classes continuing as usual to assess whether children sit less, move more and improve their wellbeing. If effective, MAFF will provide schools and communities with an easy-to-implement toolkit to promote healthier and more active families.",[97,98,99,28],"Sedentary Behaviors","Physical Inactivity","Child Health",[101,102,103,104,105],"sedentary behaviour","physical activity","school-based intervention","family-based intervention","randomized controlled trial","2026-04-05",{"date":108,"type":41},"2026-04-13",{"date":110,"type":21},"2026-11-30",{"date":112,"type":21},"2028-12-02",{"name":114,"class":48},"Instituto Politécnico de Setúbal",{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":121,"eligibilityCriteria":122,"healthyVolunteers":11,"sex":17,"minAge":123,"maxAge":124,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":128,"conditions":129,"keywords":133,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":49},"100613701","pilot-testing-real-time-engagement-for-learning-to-effectively-control-type-2-diabetes-100613701","NCT07270016","Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes","Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes: Pilot Study","REFLECT2DPilot","Inclusion criteria:\n\n* Ages 16-24 years, any sex or gender\n* Diagnosis of type 2 diabetes in childhood (younger than 18 years of age)\n* English-speaking (app in English)\n* Possession of personal smartphone that is compatible with FreeStyle Libre app\n\nExclusion Criteria:\n\n• Cognitive impairment or severe psychiatric conditions that could interfere with participation in behavioral intervention for diabetes self-management","16 Years","24 Years",{"count":126,"type":21},30,[24],"The goal of this study is to pilot test features of a new smartphone app and to gather feedback related to wearing a continuous glucose monitor (CGM) and a Fitbit device, as well as to obtain input on health behavior-focused messages delivered through the app. The study will enroll English-speaking participants aged 16-24 years who were diagnosed with type 2 diabetes before age 18. Participants will be asked to fill out surveys about diabetes, physical activity, and diet before and after wearing a CGM for 30 days. At the end of wearing the CGM, participants will complete an interview about their experience.",[130,131,98,28,132],"Diabetes Mellitus, Type 2","Hyperglycemia","Continuous Glucose Monitoring",[134,135,136,137],"adolescent","young adult","type 2 diabetes","CGM","2026-02-18",{"date":140,"type":41},"2026-02-20",{"date":142,"type":41},"2026-02-16",{"date":144,"type":21},"2026-12",{"name":146,"class":48},"University of Pittsburgh"]