[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"limb-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:limb-injury":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100551750","phase-3-pain-reduction-for-limb-injuries-in-pediatric-emergency-departments-intranasal-fentanyl-or-intranasal-ketamine-vs-oral-morphine-100551750",false,"NCT06464146","Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine","Pain Reduction for Limb Injuries in Pediatric Emergency Departments: A Randomised Clinical Trial Comparing Intranasal Fentanyl or Intranasal Ketamine to Oral Morphine","ANTAMIN","Inclusion Criteria:\n\n* Child aged 2 years to 17 years and 11 months\n* With 10 kg ≤ Weight ≤ 100 kg\n* Presenting to ED with a traumatic pain and suspected fracture(s) based on an acute deformity AND experiencing pain and\u002For functional impotence in the injured limb(s)\n* Within the first 12 hours after the injury\n* VAS pain score at ED arrival ≥ 60\u002F100 (if child ≥ 7 years) or Evendol pain score at ED arrival ≥ 7\u002F15 (if child \\\u003C 7 years)\n* Affiliated to health insurance\n* At least one signed parental informed consent\n\nExclusion Criteria:\n\n* Received narcotic pain medication prior to arrival\n* Contraindication to morphine, mentioned in SmPC\n* Hypersensitivity to ketamine or fentanyl or to excipients (sodium chloride, sodium hydroxide), or to other opioids.\n* Contraindication to fentanyl or ketamine, mentioned in SmPC\n* GCS \\\u003C15\n* Evidence of significant femur, head, chest, abdominal, or spine injury\n* Open fracture\n* Nasal trauma or complete nasal obstruction\n* Active epistaxis\n* Nasal or sinus surgery within 6 months before inclusion\n* History of high blood pressure, known coronary artery disease, congestive heart failure, acute glaucoma, increased intracranial pressure, major psychiatric disorder, hepatocellular insufficiency\n* Active or history of psychiatric disorder\n* Known pregnancy or suspicion of being pregnant\n* Breastfeeding\n* Non-French speaking parent and \u002F or child.\n* Participation to another interventional clinical research","ALL","2 Years","17 Years",{"count":21,"type":22},300,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","The purpose of this study is to determine if IN fentanyl (1.5 µg\u002Fkg) or IN ketamine (1 mg\u002Fkg) is more effective at 30 minutes than oral morphine (0.5 mg\u002Fkg) in reduction of moderate and severe pain associated with limb injuries in patients 2-17 years of age presenting to the ED.",[28],"Limb Injury",[30,31,32,33,34],"Fentanyl","Ketamin","Limb injury","Pain","Children","RECRUITING","2026-03-24",{"date":38,"type":39},"2026-03-27","ACTUAL",{"date":41,"type":39},"2025-02-26",{"date":43,"type":22},"2028-02",{"name":45,"class":46},"Assistance Publique - Hôpitaux de Paris","OTHER",5,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":60,"conditions":61,"keywords":68,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100585459","geriatric-trauma-care-program-for-living-alone-older-adults-with-injuries-100585459","NCT06902636","Geriatric Trauma Care Program for Living Alone Older Adults With Injuries","Patient Experience of Older Adults Living Alone With Injuries and Long-Term Effects of Geriatric Trauma Care Program for Living Alone Older Adults With Injuries","Inclusion Criteria:\n\n1. willing to join this study for three months\n2. with limb injuries\n3. living alone in a household\n4. aged 65 years old or older\n5. independent before a traumatic injury\n6. having a smartphone.\n\nExclusion Criteria:\n\n1. with an ISS greater than 16 (severe injuries)\n2. having cognitive impairments\n3. diagnosed with psychiatric illness","65 Years",{"count":57,"type":22},90,[59],"NA","To examine the long-term effects of the Geriatric Trauma Care Program (GTCP) regarding pain, functional disability, depression, loneliness, and health-related quality of life among older adults with traumatic injuries who live alone.",[28,62,63,33,64,65,66,67],"Older Adults","Geriatric","Geriatric Depression","Barthel Index","Quality of Life","Loneliness",[32,69,70,71],"geriatric trauma","older adults","loneliness","2025-05-13",{"date":74,"type":39},"2025-05-16",{"date":76,"type":39},"2025-03-27",{"date":78,"type":22},"2026-07-31",{"name":80,"class":46},"Kaohsiung Medical University",1]