[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"limb-ischemia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:limb-ischemia":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100622748","feasibility-and-clinical-utility-of-paired-non-invasive-hemodynamic-and-tissue-oximetry-monitoring-to-detect-limb-ischemia-in-lithotomy-positioned-surgeries-100622748",false,"NCT07387653","Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries","LIMB","Inclusion Criteria:\n\n1. Adult patients\n2. Undergoing minimally invasive pelvic surgery (such as hysterectomy, myomectomy, or endometriosis surgery)\n3. Surgery performed in lithotomy position\n4. Expected surgical duration \\> 2 hours as determined by the primary surgeon\n\nExclusion Criteria:\n\n1. Pregnant patients\n2. Procedures expected to last \\\u003C 2 hours\n3. Open surgical approaches\n4. Minor procedures\n5. Known allergy or sensitivity to adhesives used for monitoring sensors\n6. Vulnerable populations (incarcerated, elderly or pregnant)",true,"FEMALE",{"count":19,"type":20},30,"ESTIMATED","OBSERVATIONAL","The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed in lithotomy position. Thirty patients will undergo continuous intraoperative monitoring, with the primary outcome being the frequency and duration of tissue oxygen desaturation events and secondary outcomes examining correlations with postoperative limb pain, sensation, and motor function. The study is non-interventional, poses minimal risk, and aims to generate preliminary data to inform future strategies for early detection and prevention of limb ischemia and well-leg compartment syndrome",[24,25],"Neuropathy;Peripheral","Limb Ischemia",[27,28,29,30],"trendelemberg","nerve injury","position nerve injury","prolonged surgery","RECRUITING","2026-05-12",{"date":34,"type":35},"2026-05-14","ACTUAL",{"date":37,"type":35},"2026-01-29",{"date":39,"type":20},"2026-12",{"name":41,"class":42},"The University of Texas Health Science Center, Houston","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":51,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100503089","continuous-compartment-pressure-monitoring-for-compartment-syndrome-in-va-ecmo-patients-100503089","NCT05830721","Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients","Continuous Compartment Pressure Monitoring for Compartment Syndrome in Venoarterial-Extracorporeal Membrane Oxygenation Patients - A Preliminary Feasibility Study","VA-ECMO","Inclusion Criteria:\n\n* Adults ≥18 years of age\n* Peripheral Venoarterial-Extracorporeal membrane oxygenation\n* Sedated\n\nExclusion Criteria:\n\n* Any limb ischemia diagnosis prior to ECMO cannulation\n* Any severe extremity trauma that precludes insertion of device\n* Very poor prognosis (survival \\>72 hours is unlikely), which also includes severe coagulopathy. Severely coagulopathic patients are at risk for severe hemorrhage and thus may not survive fasciotomy.","ALL","18 Years",{"count":54,"type":20},6,"INTERVENTIONAL",[57],"NA","Acute compartment syndrome (ACS) is a surgical emergency that can develop in patients on extracorporeal membrane oxygenation (ECMO). ACS is a type of limb ischemia, which means that the limb, such as the arm or leg, loses blood flow. Patients on ECMO can develop this condition for many reasons, but most commonly from the ECMO procedure itself. This most commonly involves the leg. Key symptoms of ACS include severe pain, loss of pulses, loss of feeling, and inability to move the limb. However, because patients on ECMO are often sedated, ACS is difficult to diagnose as patients can not report symptoms. As a result, the only available tool for diagnosing ACS may be measurement of pressures in the limb. This is normally done with a needle-device, which is inserted into the leg for a single measurement. However, a recently developed device, called the MY01 Continuous Compartment Pressure Monitor, allows for continuous pressure readings instead of a single measurement. Multiple measurements may allow for much greater accuracy in diagnosing ACS, which may result in faster time to surgery and potentially save more limbs than single measurements. This device may also be less invasive than an older method of continuous pressure measuring, which uses a needle and tubing that is 14-gauge in size. Therefore, this study aims to compare 3 different types of methods for diagnosing ACS in patients on ECMO, which are 1) Standard of Care, 2) Standard of Care and MY01, and 3)Standard of Care and 14-gauge slit catheter.",[60,61,25,62],"Compartment Syndrome of Leg","Extracorporeal Membrane Oxygenation Complication","Limb Ischemia, Critical",[64,65,66,67],"Compartment Syndrome","Venoarterial Extracorporeal Membrane Oxygenation","Compartment Pressure Measurement","ECMO","2025-12-23",{"date":70,"type":35},"2025-12-24",{"date":72,"type":35},"2024-01-02",{"date":74,"type":20},"2027-12",{"name":76,"class":42},"Johns Hopkins University",1]