[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"limb-pain-phantom\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:limb-pain-phantom":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100494295","pain-and-disability-outcomes-in-post-amputation-patients-100494295",false,"NCT05716321","Pain and Disability Outcomes in Post Amputation Patients","Inclusion Criteria:\n\n1. Ages between 18 and 89 years old, inclusive\n2. Patients scheduled for surgical limb amputation at Penn State Hershey Medical Center\n\nExclusion Criteria:\n\n1. Patients who cannot cooperate or consent\n2. Patients who cannot understand or speak English\n3. Patients with a history of chronic regional pain syndromes\n4. Patients suffering from alcohol and\u002For drug abuse -based on previous Dx listed in the MRN\n5. BMI \\>50","ALL","18 Years","89 Years",{"count":19,"type":20},350,"ESTIMATED","OBSERVATIONAL","The objective of this study is to evaluate efficacy of varied medical and procedural therapies used to treat pain after surgical amputation of a limb. The primary outcome will be assessment of pain severity at rest and with movement as measured by pain scores on Numerical Rating Scale (NRS) 0 to 10, where 0 is not pain and 10 is the worst pain possible, taken on post-operative day 1, day 7, 30 days, 90 days, 6 months, and 1 year (+\u002F- 3 days at each time point).",[24,25,26],"Limb Pain, Phantom","Residual Limbs Pain","Disability Physical",[28],"Amputation","RECRUITING","2026-05-01",{"date":32,"type":33},"2026-05-07","ACTUAL",{"date":35,"type":33},"2023-04-05",{"date":37,"type":20},"2028-11",{"name":39,"class":40},"Milton S. Hershey Medical Center","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":41},"100519621","phase-4-a-study-of-contralateral-limb-block-100519621","NCT06045936","A Study of Contralateral Limb Block","Sciatic Block in Contralateral Limb for Treatment of Refractory Phantom and Residual Limb Pain; a Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Lower extremity amputation performed more than 12 months before study enrollment\n* PLP\u002FRLP in affected amputated limb \\> 4 on NRS26\n* Pain duration of more than 6 months despite a trial of conservative therapies for at least 2 months, including oral medications, topical medicines, physical therapy, and physical modalities (i.e., heat, cold, transcutaneous electrical nerve stimulation, phonophoresis)\n* Willingness to undergo image guided diagnostic nerve block\n\nExclusion Criteria:\n\n* Refusal \u002F inability to participate or provide consent\n* Contraindications to diagnostic nerve block\n* Non-neurogenic source of PLP\u002FRLP\n* Current opioid use \\> 50 morphine milligram equivalents per day\n* Any interventional pain treatment in the residual limb within the last 30 days\n* Severe uncontrolled medical condition (i.e., hypertensive crisis, decompensated hypothyroidism)\n* Use of investigational pain drug within past 30 days or other concurrent clinical trial enrollment",{"count":50,"type":20},20,"INTERVENTIONAL",[53],"PHASE4","This research is being done to determine if an anesthetic like Lidocaine, may be effective when injected around the sciatic nerve of the intact limb in patients with limb loss pain on the contralateral side.",[24],"2026-01-03",{"date":58,"type":33},"2026-01-06",{"date":60,"type":33},"2024-06-18",{"date":62,"type":20},"2026-12",{"name":64,"class":40},"Mayo Clinic"]