[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"liver-disease-parenchymal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:liver-disease-parenchymal":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100607715","quantitative-ultrasounddeepusff-vs-mri-pdff-for-liver-fat-assessment-in-masld-100607715",false,"NCT07192159","Quantitative Ultrasound(DeepUSFF) vs MRI-PDFF for Liver Fat Assessment in MASLD","Evaluation of a Quantitative Ultrasound Model(DeepUSFF) for Liver Fat Quantification in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Multicenter Prospective Study Using MRI-PDFF as the Reference Standard","DeepUSFF","Inclusion Criteria:\n\n* Patients with clinically suspected MASLD based on abnormal ultrasound or liver function tests requiring liver ultrasound or MRI examination\n* BMI ≥25 kg\u002Fm² or waist circumference \\>90 cm (male) or \\>80 cm (female), suggesting high likelihood of fatty liver disease\n* Living liver transplant donors requiring preoperative liver ultrasound or MRI examination\n* Age ≥18 years\n* Understanding and signing informed consent\n\nExclusion Criteria:\n\n* Significant alcohol consumption in the past 2 years:\n\nMale: ≥30-60g\u002Fday average alcohol intake Female: ≥20-50g\u002Fday average alcohol intake\n\n-Chronic liver disease:\n\nHistological diagnosis of chronic liver disease HBsAg positive Anti-HCV positive Other suspected chronic liver diseases\n\n-Liver failure:\n\nSerum albumin \\\u003C3.2 g\u002FdL INR \\>1.3 Direct bilirubin \\>1.3 mg\u002FdL\n\n* History of esophageal varices, ascites, hepatic encephalopathy, or acute biliary obstruction\n* History of liver cancer diagnosis or treatment\n* History of liver surgery\n* Pregnancy\n* Inability to obtain adequate liver ultrasound imaging:\n\nPatient cooperation impossible Inadequate image acquisition as determined by investigator\n\n-Inability to obtain adequate liver MRI imaging: Patient cooperation impossible Severe obesity preventing MRI examination MRI contraindications (cardiac pacemaker, etc.) Other factors preventing adequate imaging as determined by investigator","ALL","18 Years",{"count":20,"type":21},62,"ESTIMATED","INTERVENTIONAL",[24],"NA","This multicenter prospective study aims to evaluate the correlation between quantitative ultrasound fat fraction (USFF) and MRI-PDFF (Proton Density Fat Fraction) for liver fat quantification in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). The study will compare the diagnostic accuracy of quantitative ultrasound imaging against MRI-PDFF as the reference standard.",[27,28,29],"Metabolic Dysfunction-Associated Steatotic Liver Disease","Hepatic Steatosis","Liver Disease Parenchymal",[31,32,33,34,35,36],"Metabolic dysfunction-associated steatotic liver disease","Quantitative ultrasound","MRI-PDFF","Liver fat quantification","Hepatic steatosis","Deep learning","RECRUITING","2025-09-17",{"date":40,"type":41},"2025-09-25","ACTUAL",{"date":43,"type":41},"2025-06-24",{"date":45,"type":21},"2026-06-30",{"name":47,"class":48},"Seoul National University Hospital","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100544678","changes-in-the-lipidomic-immunological-and-mirna-profile-in-patients-undergoing-a-dietary-program-or-bariatric-surgery-100544678","NCT06372015","Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery","Changes in the Lipidomic, Immunological and Circulating microRNA Profile in Patients With Hepatobiliary Pathology, Suffering From Morbid Obesity Undergoing a Dietary Program or Bariatric Surgery","Inclusion Criteria:\n\n* Obese patients (BMI \\>30kg\u002Fm2) suffering from hepato-biliary pathology diagnosed by Fibroscan\n* Adult patients (\\>18 years).\n\nExclusion Criteria:\n\n* Patients who are not obese or not affected by hepato-biliary pathology",{"count":57,"type":21},60,"OBSERVATIONAL","Obesity is a chronic disease characterized phenotypically by an increase in body weight (BMI\\>30 kg\u002Fm2) and by a series of associated pathologies, such as hypertension, diabetes, hepatic steatosis.\n\nThe association of these pathologies compromises the patient's survival and quality of life. The multifactorial origin of obesity makes its etiopathology difficult to manage. It is often possible to follow only one therapeutic strategy, especially after the so-called standard treatments, such as dietary intervention and physical activity, have not brought benefit to the patient. In these cases, an appropriate treatment for the patient to enjoy significant weight loss is bariatric surgery.\n\nBariatric surgery refers to all those interventions aimed at reducing weight in those suffering from obesity, and treating the diseases associated with it.\n\nAmong the different types of bariatric surgery, the techniques most used in common clinical practice are intragastric balloons, gastric by pass (RYGB) and sleeve gastrectomy.\n\nThe choice of the surgeon, assisted by the multidisciplinary team, is binding in the choice of the type of operation to which the patient will be subjected.",[61,29],"Obesity",[61,63,64],"Liver Diseases","Bariatric Surgery","2025-04-02",{"date":67,"type":41},"2025-04-04",{"date":69,"type":41},"2024-06-01",{"date":71,"type":21},"2026-06-01",{"name":73,"class":48},"Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis",1]