[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"liver-stiffness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:liver-stiffness":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100587750","effect-of-malnutrition-on-liver-and-spleen-stiffness-in-children-100587750",false,"NCT06932445","Effect of Malnutrition on Liver and Spleen Stiffness in Children","Impact of Malnutrition on Liver and Spleen Stiffness in Children Evaluated by Shear Wave Elastography","SWE","Inclusion Criteria:\n\n* Children aged 6 to 18 years.\n* Diagnosis of malnutrition based on World Health Organization (WHO) criteria (for malnutrition group).\n* Healthy children without any chronic illness (for control group).\n\nExclusion Criteria:\n\n* Children with chronic diseases (e.g., liver disease, diabetes, immunocompromised conditions).\n* Children who have previously undergone liver or spleen surgery.\n* Children with inability to cooperate during elastography measurement.",true,"ALL","1 Month","18 Years",{"count":22,"type":23},300,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the effect of malnutrition on liver and spleen stiffness in children using shear wave elastography. Two groups of participants will be enrolled: children diagnosed with malnutrition and age-matched healthy controls. Organ stiffness measurements will be compared between the two groups to assess the impact of malnutrition on liver and spleen tissue properties.",[27,28,29,30],"Malnutrition in Children","Liver Stiffness","Spleen Stiffness","Shear Wave Elastography",[32,28,29,30,33],"Malnutrition","Children","RECRUITING","2025-04-10",{"date":37,"type":38},"2025-04-17","ACTUAL",{"date":35,"type":38},{"date":41,"type":23},"2025-05-20",{"name":43,"class":44},"Mehmet Akif AĞIR","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":18,"minAge":20,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":45},"100551690","multi-parametric-magnetic-resonance-imaging-for-the-precise-diagnosis-and-quantitative-study-of-liver-steatosis-inflammation-and-fibrosis-in-chronic-liver-disease-100551690","NCT06463366","Multi-parametric Magnetic Resonance Imaging for the Precise Diagnosis and Quantitative Study of Liver Steatosis, Inflammation, and Fibrosis in Chronic Liver Disease.","Inclusion Criteria:\n\n1. Chronic liver disease (including viral hepatitis, alcoholic hepatitis, non alcoholic steatohepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, etc..)\n2. Age range of 18 to 75 years old\n3. Accept systematic antiviral therapy or hormone or ursodesoxycholic acid or supportive liver protection therapy\n\nExclusion Criteria:\n\n1. Age less than 18 years\n2. Unable or unwilling to give informed consent\n3. Contra-indications to MRI\n4. Electrical implants such as cardiac pacemakers or perfusion pumps\n5. Ferromagnetic implants such as aneurysm clips, surgical clips, prostheses, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants\n6. Ferromagnetic objects such as jewelry or metal clips in clothing\n7. Pregnant subjects\n8. Pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions","75 Years",{"count":54,"type":23},100,"To construct a novel, non-invasive, accurate, and convenient method to achieve the degree of liver damage is an important general problem in the management of patients with chronic liver disease. The investigators would like to develop non invasive advanced Magnetic Resonance Imaging (MRI) techniques (MR elastography, MRI-PDFF) to assess the degree of liver damage in patients with chronic liver disease. These techniques could reach high diagnostic performance for detection of liver fibrosis, inflammation and liver fat content; and could decrease the number of liver biopsies, which have risks and sample only a small portion of the liver.",[28],"2025-02-26",{"date":59,"type":38},"2025-02-28",{"date":61,"type":38},"2022-06-14",{"date":63,"type":23},"2025-09-01",{"name":65,"class":44},"Shengjing Hospital"]