[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"local-anesthesia-infiltration\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:local-anesthesia-infiltration":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,81,120],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100645310","efficacy-of-facial-massager-in-reducing-intra-oral-injection-pain-in-pediatric-patients-100645310",false,"NCT07682181","Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric Patients","Efficacy of a Vibrating Facial-T- Massager as an Adjunct to Topical Anesthesia in Reducing Intraoral Injection Pain in Children: A Randomized Controlled Trial.","Inclusion Criteria:\n\n* Children aged 4-12 years requiring local anesthesia\n* Cooperative behaviour (frankl rating 3,4)\n\nExclusion Criteria:\n\n* History of allergy to benzocaine\n* acute infection at the site\n* special healthcare needs affecting sensory perception\n* Medically compromised children\n* unco-operative children\n* those who do not consent.",true,"ALL","4 Years","12 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","Abstract\n\n* Background: Local anesthesia is a primary source of anxiety in pediatric dentistry.\n* Objective: To evaluate if mechanical vibration from a low-cost facial massager reduces pain and anxiety during injections using the Gate Control Theory.\n* Design: Prospective Randomized Controlled Trial .",[28],"Local Anesthesia Infiltration",[30,31,32,33,34],"local anesthesia","local infiltration","massager","vibrating device","Topical Benzocaine","NOT_YET_RECRUITING","2026-06-26",{"date":38,"type":39},"2026-07-02","ACTUAL",{"date":41,"type":22},"2026-06-01",{"date":43,"type":22},"2026-12-31",{"name":45,"class":46},"Government Dental College and Hospital, India","OTHER_GOV",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100625929","intraoperative-bupivacaine-injection-to-reduce-acute-and-chronic-pain-after-tvttvt-o-surgery-randomized-double-blind-trial-100625929","NCT07429019","Intraoperative Bupivacaine Injection to Reduce Acute and Chronic Pain After TVT\u002FTVT-O Surgery. Randomized Double-Blind Trial","Reduction of Post-surgery Pelvic Pain by Bupivacaine Injection During TVT\u002F TVT-O Procedure","PAIN-TVT","Inclusion Criteria:\n\n* Women aged 18 years or older\n* Scheduled to undergo vaginal surgery including TVT or TVT-O procedure for stress urinary incontinence\n* Able and willing to provide written informed consent\n* Willing to complete postoperative follow-up assessments for at least 6 months\n\nExclusion Criteria:\n\n* Planned concomitant abdominal, laparoscopic, or robotic surgery\n* Pre-existing chronic pelvic pain\n* Diagnosis of fibromyalgia\n* Diagnosis of endometriosis\n* Inability to complete follow-up assessments\n* Inability to provide informed consent","FEMALE","18 Years",{"count":58,"type":22},60,[25],"This randomized, double-blind controlled trial will evaluate whether intraoperative injection of bupivacaine at the sling insertion site reduces postoperative pelvic and thigh pain in women undergoing TVT or TVT-O surgery for stress urinary incontinence. Women aged 18 years and older scheduled for vaginal surgery including a mid-urethral sling procedure will be randomly assigned to receive either 0.5% bupivacaine or saline injection at the surgical site at the end of the procedure.\n\nPostoperative pain will be assessed using the Numerical Rating Scale (NRS) within 24 hours after surgery, at one month, and at least six months postoperatively. The study will also evaluate opioid consumption and examine the relationship between early postoperative pain and the development of chronic postsurgical pain. The results may help determine whether local anesthetic injection during sling surgery can improve short- and long-term pain outcomes.",[62,63,64,28],"Pain After Surgery","PSP","Chronic Pain Syndrome",[66,67,68,69,70],"TVT","TVTO","Mid Urethral Sling","pain","chronic pain syndrom","2026-06-20",{"date":73,"type":39},"2026-06-23",{"date":75,"type":22},"2026-07-01",{"date":77,"type":22},"2027-10-01",{"name":79,"class":80},"Hadassah Medical Organization","OTHER",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":23,"phases":91,"briefSummary":92,"conditions":93,"keywords":99,"overallStatus":109,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":119},"100611379","peng-block--lia-for-endoprosthesis-surgery-100611379","NCT07239817","PENG Block + LIA For Endoprosthesis Surgery","PENG 360°: PENG Block + LIA Nella Endoprotesi di Anca.","PENG 360°","Inclusion Criteria:\n\n* Provision of signed and dated informed consent form.\n* Scheduled for hip endoprosthesis surgery for femoral fracture with an anterior approach.\n* Age 18 years or older.\n* Willing and able to comply with the study protocol.\n\nExclusion Criteria:\n\n* Failure to provide informed consent.\n* Age less than 18 years.\n* Known allergy to local anesthetics or other medications used in the protocol.\n* Presence of infection at the planned injection site.\n* Pre-existing hip prosthesis or prior major surgery on the same hip (e.g., revision surgery).\n* ASA physical status class \\> IV.\n* Administration of intraoperative opiates or conversion to general anesthesia.",{"count":90,"type":22},100,[25],"The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery. The main questions it aims to answer are:\n\n* Is the new local anesthesia technique as effective as standard spinal anesthesia in managing pain during the first two days after surgery?\n* Does the new technique allow participants to move their leg sooner after the operation?\n\nResearchers will compare the new local anesthesia technique (numbing medicine injected directly around the hip joint) to standard spinal anesthesia (a numbing injection in the back) to see if the new technique works just as well for pain control while possibly causing fewer side effects like nausea.\n\nParticipants who join this study will be randomly placed into one of two groups.\n\nOne group will receive the standard spinal anesthesia before their surgery.\n\nThe other group will receive the new local anesthesia technique before their surgery.\n\nAfter the operation, researchers will track the amount of extra pain medicine each participant uses and will check their ability to move their hip, knee, and foot.",[94,95,96,97,98,28],"Hip Fractures","Arthroplasty, Replacement, Hip","Pain, Postoperative","Anesthesia and Analgesia","Nerve Block",[100,101,102,103,104,105,106,107,108],"Pericapsular Nerve Group Block","PENG block","Local Infiltration Analgesia","Spinal Anesthesia","Hip Arthroplasty","Postoperative Pain","Femoral Fractures","Ultrasound Guidance","Early Mobilization","RECRUITING","2026-06-10",{"date":112,"type":39},"2026-06-12",{"date":114,"type":39},"2025-12-09",{"date":116,"type":22},"2026-12-30",{"name":118,"class":80},"ASST Gaetano Pini-CTO",1,{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":127,"enrollmentInfo":128,"targetDuration":4,"studyType":23,"phases":130,"briefSummary":131,"conditions":132,"keywords":4,"overallStatus":109,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":142,"leadSponsor":144,"locationsCount":119},"100580456","ultrasound-guided-versus-surgical-rectus-sheath-block-versus-local-anesthesia-infiltration-for-postoperative-analgesia-in-patients-undergoing-total-abdominal-hysterectomy-100580456","NCT06837532","Ultrasound Guided Versus Surgical Rectus Sheath Block Versus Local Anesthesia Infiltration for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy","Ultrasound Guided Versus Surgical Rectus Sheath Block Versus Local Anesthesia Infiltration for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy: A Randomized Trial","Inclusion Criteria:\n\n* Age from 18 to 65 years old.\n* American Society of Anesthesiologists (ASA) physical status I - II.\n* Patients scheduled for elective total abdominal hysterectomy under general anesthesia.\n\nExclusion Criteria:\n\n* Hepatic, renal or cardiac disease.\n* Any known allergy to local anesthetic.\n* Physical or mental conditions which may vaguely measure postoperative pain following surgery.\n* History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs) or central nervous system (CNS) depressants as antiepileptic, and bleeding disorders.","65 Years",{"count":129,"type":22},90,[25],"The aim of this work is to compare the efficacy and safety of the effectiveness and safety of ultrasound-guided surgical rectus sheath block and local anesthetic infiltration for postoperative analgesia in patients undergoing total abdominal hysterectomy.",[133,134,135,28,136,137],"Ultrasound","Surgical","Rectus Sheath Block","Postoperative Analgesia","Total Abdominal Hysterectomy","2025-02-20",{"date":140,"type":39},"2025-02-21",{"date":138,"type":39},{"date":143,"type":22},"2025-08-01",{"name":145,"class":80},"Ain Shams University"]