[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"local-calcitriol-delivery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:local-calcitriol-delivery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100608345","clinical-evaluation-of-local-calcitriol-delivery-on-maxillary-canine-retraction-100608345",false,"NCT07200349","Clinical Evaluation of Local Calcitriol Delivery on Maxillary Canine Retraction","CALCR25","Inclusion Criteria:\n\n1. Presence of class I malocclusion requiring bilateral extraction of the maxillary first premolars and subsequent canine retraction.\n2. Presence of class II malocclusion requiring bilateral extraction of the maxillary first premolars and subsequent canine retraction.\n3. Age range between 13 and 35 years to include both adolescent and adult patients suitable for orthodontic treatment.\n4. Presence of permanent dentition.\n5. Good oral hygiene.\n\nExclusion Criteria:\n\n1. History of chronic systemic disease.\n2. Presence of active gingival or periodontal disease.\n3. Known allergy or hypersensitivity to vitamin D.\n4. Pregnancy or lactation.\n5. History of previous orthodontic treatment.\n6. Presence of craniofacial anomalies affecting bone physiology.",true,"ALL","13 Years","35 Years",{"count":21,"type":22},22,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction. It is a split-mouth randomized clinical trial, where Calcitriol will be locally applied on one side of the maxilla, and the other side will serve as control.",[28,29,30],"Maxillary Canine Retraction","Local Calcitriol Delivery","Orthodontic Tooth Movement",[32,33,34,35],"Calcitriol","Vitamin D3","Canine Retraction","Split-mouth Trial","NOT_YET_RECRUITING","2025-09-30",{"date":39,"type":40},"2025-10-01","ACTUAL",{"date":42,"type":22},"2025-11-01",{"date":44,"type":22},"2026-10",{"name":46,"class":47},"Al-Azhar University","OTHER"]