[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"locally-advanced-esophageal-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:locally-advanced-esophageal-cancer":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100644605","comprehensive-perioperative-program-based-on-prehabilitation-nutritional-intervention-and-psychological-support-for-patients-with-locally-advanced-operable-oesophagogastric-cancer-100644605",false,"NCT07671625","Comprehensive Perioperative Program Based on Prehabilitation, Nutritional Intervention and Psychological Support for Patients With Locally Advanced Operable Oesophagogastric Cancer","A Comprehensive Preoperative and Postoperative Program Consisting Of Active Physical Therapy, A Comprehensive Nutritional Plan, And Psychological Support For Patients With Locally Advanced, Resectable Cancer Of The Esophagus, Gastroesophageal Junction, and Stomach","OESOFIT","Inclusion Criteria:\n\n* Consent to participate in the study\n* Age ≥ 18 years\n* Patients with locally advanced esophageal or gastric cancer indicated for comprehensive perioperative treatment\n* Resectable disease\n* ECOG performance status 0-2\n* Ability to participate in a fitness program\n* Willingness to follow a nutritional plan and recommendations\n\nExclusion Criteria:\n\n* Disseminated disease","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Perioperative chemotherapy (CHT) or CHT\u002FRT combined with surgery is the standard therapeutic approach for the treatment of locally advanced cancer of the esophagus, gastroesophageal junction (GEJ), and stomach. Comprehensive cancer treatment is associated with high perioperative morbidity and mortality. Serious postoperative complications occur in up to 20-80% of patients undergoing esophagectomy. The impact of nutritional status and overall physical condition on surgical outcomes and overall treatment has been demonstrated many times. The concept of pre-rehabilitation\u002Fpre-optimization, which involves establishing an individualized nutritional plan, monitoring and managing physical activity, and providing comprehensive supportive oncological and psychological care as early as during neoadjuvant CHT or CHT\u002FRT, is a prerequisite for improving perioperative and 30-day postoperative morbidity and mortality.",[27,28,29],"Locally Advanced Esophageal Cancer","Gastroesophageal Junction Cancer","Gastric Cancer",[31,32,33,34,35,36],"autonomic nervous system","physiotherapy","gastric cancer","nutritional intervention","psychologic support","esophageal cancer","RECRUITING","2026-06-25",{"date":40,"type":41},"2026-06-26","ACTUAL",{"date":43,"type":41},"2023-05-02",{"date":45,"type":21},"2026-12-31",{"name":47,"class":48},"Masaryk Memorial Cancer Institute","OTHER"]