[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"loco-regional-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:loco-regional-anesthesia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100600798","comparison-of-loco-regional-analgesic-techniques-in-patients-undergoing-video-assisted-thoracoscopic-surgery-vats-100600798",false,"NCT07102173","Comparison of Loco-regional Analgesic Techniques in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS)","Management Protocol for Comparison of Loco-regional Analgesic Techniques in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS)","PRoGEVATS","Inclusion Criteria:\n\n* Adult patients\n* Signed informed consent\n* Elective unilateral surgery\n\nExclusion Criteria:\n\n* Minor patients\n* BMI \\> 40\n* Unstable neurological disorders\n* Known allergy to acetaminophen and NSAIDs\n* Chronic renal failure (stage \\> 4, whith GFR between 29 and 15 mL\u002Fmin)\n* Patient refusal\n* Chronic use of NSAIDs and opioids in the 3 months prior to surgery\n* Contraindications to peripheral block (infection al the insertion site, allergy to local anesthetics, severe coagulation disorders)","ALL","18 Years",{"count":20,"type":21},72,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare two loco-regional analgesic techniques:\n\n1. Intercostal nerve block: Performed by the surgeon intraoperatively before final lung re-expansion, involving the administration of 20 mL of 0.5% levobupivacaine using a 27G needle into the subpleural space of the thoracotomy access site and adjacent intercostal spaces.\n2. Ultrasound-guided ESPB: Performed by an anesthesiologist under surgical asepsis with the patient in a seated position. After identifying the target transverse process, a linear ultrasound probe is placed sagittally approximately 2 cm from the midline. The needle (22G, 50 mm) is inserted in-plane in a cranio-caudal direction until contacting the transverse process. After confirming proper injection by observing anesthetic spread between the erector spinae muscle and transverse process, a total of 30 mL of 0.375% ropivacaine is administered.\n\nThis protocol is intended for patients undergoing video-assisted thoracoscopic surgery (VATS) for pneumonectomies, lobectomies, wedge resections, and bullectomies.\n\nPrimary Endpoint:QoR Score at 24 hours (validated questionnaires. Secondary Endpoints: Intraoperative NOL, QoR at 48-72 hours, opioid consumption at 12-24-48 hours, NLR at 24 hours, CPSP incidence at 3 months.",[27],"Loco-regional Anesthesia",[29,30,31,32,33],"VATS","post-operative analgesia","loco-regional anesthesia","ESPB","Intercostal nerve block","NOT_YET_RECRUITING","2025-07-28",{"date":37,"type":38},"2025-08-03","ACTUAL",{"date":40,"type":21},"2025-08-01",{"date":42,"type":21},"2026-04",{"name":44,"class":45},"ASST Sette Laghi","OTHER"]