[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"long-term-oxygen-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:long-term-oxygen-therapy":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100608232","impact-of-home-non-invasive-ventilation-in-patients-with-chronic-obstructive-pulmonary-disease-discharged-from-assiut-university-hospital-100608232",false,"NCT07198880","Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From Assiut University Hospital","Inclusion Criteria:\n\n* Patients more than 18 year old.\n* Severe COPD (classified as GOLD stage Ⅲ and IV), confirmed by FEV₁\u002FFVC \\\u003C 70% and FEV₁ \\\u003C 50% of the predicted value. (9)\n* Persistent hypercapnia (PaCO₂ ≥ 60 mmHg ≥2 weeks after resolution of acute exacerbation and compliant on optimal medical therapy with or without long term oxygen therapy\n\nExclusion Criteria:\n\n* Other significant respiratory disorders (e.g,history suggestive OSA, Body Mass Index more than 30, pneumothorax, bullous lung disease, advanced interstitial lung diseases , restrictive thoracic wall diseases , neuromuscular disease).\n* Undergone intubation or tracheostomy prior to NIV initiation during the last 2 months.\n* Those using addictive narcotic medications.\n* Comorbidities and diseases that might confound survival outcomes (e.g., malignancy, advanced hepatic or renal diseases).\n* Pregnancy\n* Refusal or Inability to tolerate NIV during initiation and adaptation phase.\n* Expected Poor compliance (patients deemed unlikely to adhere to nightly NIV use such as no family support, severe frailty).\n* Withdrawal criteria: stopping bipap or medical treatment, voluntary withdrawal by the participant, failure to attend scheduled visits, and significant clinical deterioration requiring alternative management during the study period","ALL","18 Years","80 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the impact of long-term home non-invasive ventilation (NIV) on patients with COPD",[26,27,28,29,30,31,32],"COPD","COPD (Chronic Obstructive Pulmonary Disease)","Ventilation Therapy","Non Invasive Ventilation (NIV)","BiPAP","Hypercapnia","Long Term Oxygen Therapy","NOT_YET_RECRUITING","2025-09-27",{"date":36,"type":37},"2025-09-30","ACTUAL",{"date":39,"type":20},"2026-01-01",{"date":41,"type":20},"2028-01-01",{"name":43,"class":44},"Assiut University","OTHER"]