[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"longstanding-persistent-atrial-fibrillation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:longstanding-persistent-atrial-fibrillation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100327687","medtronic-terminate-af-study-100327687",false,"NCT03546374","Medtronic Terminate AF Study","Irrigated Radio Frequency Ablation to Terminate Non-Paroxysmal Atrial Fibrillation (Terminate AF Study)","Inclusion Criteria:\n\n* History of non-paroxysmal AF (persistent or longstanding persistent)\n* Concomitant indication for non-emergent open-heart surgery, eg,\n\n  1. Coronary artery bypass grafting\n  2. Valve repair or replacement\n* Able to take the anticoagulant warfarin or novel oral anticoagulants (NOAC)\n\nExclusion Criteria:\n\n* Wolff-Parkinson-White syndrome\n* New York Heart Association (NYHA) Class = IV\n* Left Ventricular Ejection Fraction ≤ 30%\n* Need for emergent cardiac surgery (ie, cardiogenic shock) or redo open heart surgery\n* Previous AF ablation, atrioventricular (AV) -nodal ablation, or surgical Maze procedure\n* Contraindication for anticoagulation therapy\n* Left atrial diameter \\> 6.0 cm\n* Preoperative need for an intra-aortic balloon pump or intravenous inotropes\n* Renal failure requiring dialysis or hepatic failure\n* Life expectancy of less than 1 year\n* Predicted risk of operative mortality \\>10% as assessed by STS Risk Calculator\n* Pregnancy or desire to be pregnant within 12 months of the study treatment\n* Current diagnosis of active systemic infection\n* Active endocarditis\n* Documented MI 30 days prior to study enrollment\n* Current or planned participation in an investigational or observational drug or device trial related to the treatment of atrial arrhythmias","ALL","18 Years",{"count":19,"type":20},160,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to demonstrate the safety and effectiveness of the Cardioblate iRF and CryoFlex hand held devices for the treatment of non-paroxysmal atrial fibrillation (AF).",[26,27],"Persistent Atrial Fibrillation","Longstanding Persistent Atrial Fibrillation","RECRUITING","2026-05-07",{"date":31,"type":32},"2026-05-14","ACTUAL",{"date":34,"type":32},"2018-11-15",{"date":36,"type":20},"2026-12",{"name":38,"class":39},"Medtronic Cardiac Surgery","INDUSTRY",15]