[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"low-energy-availability\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:low-energy-availability":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,44,74,103,126,152],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100638662","effects-of-resistance-training-on-women-with-functional-hypothalamic-amenorrhea-100638662",false,"NCT07612735","Effects of Resistance Training on Women With Functional Hypothalamic Amenorrhea","Impact of Strength Training on Mental Health and Physical Fitness in Women With Functional Hypothalamic Amenorrhea","Inclusion Criteria:\n\n* General Profile: Active women aged 18 to 35 years.\n* FHA Group: Clinical diagnosis of Functional Hypothalamic Amenorrhea, defined as the absence of menstruation for at least three consecutive months not attributable to other endocrine disorders.\n* Control Group (EU): Eumenorrheic women with regular ovulatory cycles lasting between 24 and 35 days during the previous six months.\n* Commitment: Agreement to participate in a supervised 8-week resistance training program and provision of medical documentation confirming menstrual status.\n\nExclusion Criteria:\n\n* Hormonal Status: Current use of any hormonal contraceptives.\n* Medical Conditions: Diagnosed endocrine disorders such as Polycystic Ovary Syndrome (PCOS), hyperandrogenism, or thyroid dysfunction.\n\nPregnancy: Current pregnancy.\n\n* Physical Activity History: Engagement in any structured resistance training program during the three months prior to the start of the intervention.\n* General Health: Any medical condition that could interfere with the study protocol or the ability to perform physical exercise.",true,"FEMALE","18 Years",{"count":20,"type":21},28,"ESTIMATED","INTERVENTIONAL",[24],"NA","Functional hypothalamic amenorrhea (FHA) is a condition where women lose their menstrual periods, typically due to a combination of stress and insufficient calorie intake to fuel their daily physical activity (low energy availability). Standard medical advice often requires these women to completely stop exercising to recover their energy balance and hormones. However, this \"complete rest\" approach can cause severe anxiety for active individuals and removes the necessary mechanical loading that keeps bones strong.\n\nThis study evaluates the safety and effectiveness of an 8-week supervised resistance training (weightlifting) program as a realistic alternative treatment for active women with FHA. The researchers compare a group of women experiencing FHA to a control group of women with regular menstrual cycles. Over the 8 weeks, participants complete three moderate-intensity, full-body weightlifting sessions per week.\n\nThe primary goal is to determine if women with FHA can successfully recover their menstrual cycles while continuing to lift weights. Additionally, the study monitors changes in muscle strength, jumping performance, body composition, resting heart rate, and psychological well-being. Ultimately, this study aims to provide healthcare providers and coaches with evidence-based strategies that allow female athletes to safely maintain their athletic identity and physical health during recovery.",[27,28,29,30],"Amenorrhea","Functional Hypothalamic Amenorrhea (FHA)","Low Energy Availability","Relative Energy Deficiency in Sport","NOT_YET_RECRUITING","2026-05-22",{"date":34,"type":35},"2026-05-29","ACTUAL",{"date":37,"type":21},"2026-05-15",{"date":39,"type":21},"2026-07-25",{"name":41,"class":42},"Catholic University of Murcia","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":43},"100603401","preventing-athlete-under-fueling-through-nutrition-100603401","NCT07136038","Preventing Athlete Under-fueling Through Nutrition.","Prevention and Education for RED-S Through Fueling Outcomes and Research in Metabolic Health","PERFORM","Inclusion Criteria:\n\n1. Age range: from 18 years of age and up\n2. Currently active and NCAA-eligible (including academic standing) member of any Case Western Reserve University (CWRU) Athletic Team\n3. Signed Informed Consent\n\nExclusion Criteria:\n\n1. Under 18 years of age\n2. Pregnant women or women who are nursing\n3. Unwilling to provide anthropometrics, questionnaires or other collection needs\n4. History of a diagnosed disordered eating","ALL",{"count":54,"type":21},300,[24],"The goal is to improve nutrition screening and support for Division III athletes.\n\nThe study will use standard, low-risk nutrition screening methods, such as measuring height, weight, grip strength, and body composition, as well as having athletes complete questionnaires. Dietitians trained in sports nutrition will provide nutrition advice based on these screenings.\n\nData will be collected at three points during the season: before the season starts, mid-season, and after the season ends. This study builds on earlier research conducted at Case Western Reserve University that showed nutrition support can improve athletes' health and performance.",[58,30,29],"Athlete",[60,61,62,63],"collegiate","sport","lean body mass","fat mass","RECRUITING","2026-03-02",{"date":67,"type":35},"2026-03-04",{"date":69,"type":35},"2025-08-19",{"date":71,"type":21},"2026-12-31",{"name":73,"class":42},"Case Western Reserve University",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":16,"sex":52,"minAge":18,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":43},"100622006","characteristics-of-performance-in-collegiate-cheerleaders-and-dancers-100622006","NCT07378007","Characteristics of Performance in Collegiate Cheerleaders and Dancers","Body Composition and Characteristics of Performance in Collegiate Cheerleaders and Dancers","Inclusion Criteria:\n\n* Must be a part of either the Florida State University dance or cheer team\n* Sex: Female\n* Age: 18-30\n* BMI: Normal (18.5 - 24.9 kg\u002Fm2)\n\nExclusion Criteria:\n\n* Not biologically female\n* Have a diagnosed and unresolved eating disorder\n* Not weight stable (defined as a gain\u002Floss of more than \\~7.7 lbs in the past 2 months)\n* Participants who are pregnant or who become pregnant during the study","30 Years",{"count":83,"type":21},65,"OBSERVATIONAL","This study aims to investigate performance differences between collegiate cheerleaders and dancers classified as normal weight obese and those classified as normal weight lean. The study will assess differences in physical performance, lifestyle behaviors, muscle quality, and nutrition-related factors between groups. Performance testing, body composition assessment, and questionnaire-based measures will be used to characterize these relationships.",[29,87,88],"Physical Performance","Nutrition",[90,91,92,93,88],"Body Composition","Energy Availability","Physical Fitness","Division I Collegiate Cheerleaders and Dancers","2026-01-28",{"date":96,"type":35},"2026-01-30",{"date":98,"type":35},"2025-08-03",{"date":100,"type":21},"2026-05-01",{"name":102,"class":42},"Florida State University",{"id":104,"slug":4,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":16,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":111,"conditions":112,"keywords":113,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":125,"locationsCount":43},"100619661","NCT07347522","Body Composition and Lifestyle Factors in ROTC","Associations Between Body Composition, Energy Availability, and Lifestyle Factors in Reserve Officer Training Corps Cadets","Inclusion Criteria:\n\n* currently enrolled as a Reserve Officer Training Corps Cadets\n* 18 years or older\n\nExclusion Criteria:\n\n* pregnancy\n* injuries preventing full participation in ROTC training or activities",{"count":110,"type":21},45,"This study aims to investigates the relationships between body composition, sleep, diet, and physical fitness in ROTC cadets. Further, it aims to evaluate the accuracy of body composition screening methods and identify lifestyle factors linked to performance. Methods include body composition testing, surveys, accelerometry, and fitness score collection from cadets.",[29,87,88],[114,115,116,117,118],"body composition","energy availability","physical fitness","Reserve Officer Training Corp","nutrition","2026-01-09",{"date":121,"type":35},"2026-01-16",{"date":123,"type":35},"2025-10-01",{"date":100,"type":21},{"name":102,"class":42},{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":16,"sex":52,"minAge":18,"maxAge":4,"enrollmentInfo":134,"targetDuration":4,"studyType":84,"phases":4,"briefSummary":136,"conditions":137,"keywords":138,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":148,"leadSponsor":150,"locationsCount":43},"100610826","energy-availability-and-its-impact-in-elite-triathletes-100610826","NCT07232628","Energy Availability and Its Impact in Elite Triathletes","Energy Availability in Elite Triathletes: Impact on Performance and Injury Risk","TriatLEA","Inclusion Criteria:\n\n* Age ≥18 years\n* Healthy individuals\n* Training ≥15 hours\u002Fweek in triathlon\n\nExclusion Criteria:\n\n* Smokers\n* Use of prohibited substances (WADA list) without medical justification\n* Existing injuries or illnesses that could worsen due to participation",{"count":135,"type":21},40,"This study investigates how energy availability affects performance, injury risk, and training outcomes in elite triathletes. Over two competitive seasons (2026-2027), 40 elite and sub-elite triathletes will be monitored through physiological tests, blood samples, and questionnaires. The goal is to identify markers of low energy availability and understand its impact on health and athletic performance. The study is observational and does not involve experimental treatments. Participants continue their regular training and diet while undergoing periodic assessments.",[29,30],[139,140,141,142,143],"RED-S","injury risk","performance","triathlon","biomarker","2025-11-14",{"date":146,"type":35},"2025-11-18",{"date":123,"type":35},{"date":149,"type":21},"2028-06",{"name":151,"class":42},"Bispebjerg Hospital",{"id":153,"slug":154,"hasResults":11,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":158,"eligibilityCriteria":159,"healthyVolunteers":16,"sex":52,"minAge":18,"maxAge":160,"enrollmentInfo":161,"targetDuration":4,"studyType":22,"phases":163,"briefSummary":164,"conditions":165,"keywords":168,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":177,"leadSponsor":179,"locationsCount":43},"100602382","impact-of-diet-induced-change-in-energy-balance-on-metabolism-in-endurance-athletes-100602382","NCT07122778","Impact of Diet-induced Change in Energy Balance on Metabolism in Endurance Athletes","Impact of Diet-induced Change in Energy Balance on Metabolism in Endurance Athletes: the Carpe DIEM Study","Carpe DIEM","Inclusion Criteria:\n\n* Self-identified endurance-trained sport participants\n* Training volume: \\>7 hours per week endurance training\n* Training frequency: at least 5 days per week\n\nExclusion Criteria:\n\n* Diagnosis of Relative Energy Deficiency in Sport (REDs)\n* Active eating disorder (EDE-Q)\n* Active flare of a chronic disease (e.g. inflammatory bowel disease)\n* Type 1 or 2 diabetes mellitus\n* Untreated or undergoing active treatment of anaemia (any cause)\n* Current injury which precludes undertaking high volume endurance training\n* Individuals following a habitual low-carbohydrate, high-fat diet\n* Any medical diagnosis which precludes intense exercise (e.g. untreated cardiac arrhythmia)\n* Allergy or intolerance to study foods\n* Blood donation within preceding 8 weeks of study start date\n* Use of medications that affect substrate utilisation (e.g. statins, corticosteroids, thyroxine, HRT)\n* For females: current pregnancy, breastfeeding within past 6 months or post-menopausal\n* Unable to undertake a treadmill running test\n* Participation in any research study in the past 8 weeks\n* Participation in a research study within the past year involving more than one DEXA scan\n* Unable to provide informed consent due to impaired cognitive capacity or decision-making ability","49 Years",{"count":162,"type":21},20,[24],"Recent research has suggested that increasing levels of physical activity are associated with a reduction in the independent components that contribute to total energy expenditure (such as resting metabolic rate and non-exercise movement) - this occurs to conserve energy required for physical activity where energy provision becomes scarce. There are potential deleterious health and performance consequences of a reduced energy supply to fundamental metabolic processes, putting individuals regularly undertaking high levels of physical activity, such as endurance athletes, at risk. However, this association is largely based on observational data in only moderately active populations, and it is currently unclear what role energy balance status and biological sex has on this relationship.\n\nThis research intends to address these unknowns by assessing the impact of diet-induced manipulation of energy balance (conditions of energy deficit and energy surplus) in individuals undertaking habitually high levels of physical activity on independent components of total energy expenditure (resting metabolism, exercise and non-exercise movement).\n\nMale and female athletes conducting regular moderate-to-high training volumes will undertake a randomised crossover study with a 7-day state of energy deficit and a 7-day state of energy surplus. Participants will continue to live and train as normal, but their diet will be controlled by specific food provision over the intervention periods in order to facilitate both conditions. Independent components of energy expenditure, markers of health, metabolism and performance will be measured to allow for comparison of conditions.",[166,167,29,30],"Energy Balance","Energy Deficit",[169,170,115,171],"energy deficit","energy balance","physical activity","2025-08-11",{"date":174,"type":35},"2025-08-14",{"date":176,"type":21},"2025-08",{"date":178,"type":21},"2027-05",{"name":180,"class":42},"University of Bath"]