[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"low-flow-low-gradient-aortic-stenosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:low-flow-low-gradient-aortic-stenosis":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100561353","transcatheter-aortic-valve-replacement-in-severe-low-flow-low-gradient-aortic-stenosis-100561353",false,"NCT06589063","Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis","Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis: the Multicenter LOW-TAVR Registry","LOW-TAVR","Inclusion Criteria:\n\n* LFLG-AS diagnosis according to current European Society of Cardiology guidelines\n* Age 18 years or older\n* Written informed consent\n\nExclusion Criteria:\n\n* LFLG-AS pseudo-severe or non-confirmed severe aortic stenosis\n* LFLG-AS referred for medical treatment or undergoing surgery","ALL","18 Years",{"count":20,"type":21},1350,"ESTIMATED","5 Years","OBSERVATIONAL","LOW-TAVR is a real-world, retrospective and prospective, multicenter Italian registry aimed at evaluating the characteristics and clinical outcomes of patients with severe low flow, low gradient aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) and, in particular:\n\n* risk factors\n* gender differences\n* comorbidities\n* pharmacological treatment\n* TAVR procedural characteristics\n* periprocedural and in-hospital complications\n* clinical outcome at 30-day, 1-year, 2-year and 5-year follow-up",[26],"Low Flow, Low Gradient Aortic Stenosis",[28,29,30,31],"aortic stenosis","transcatheter aortic valve replacement","clinical outcomes","interventional cardiology","RECRUITING","2026-04-01",{"date":35,"type":36},"2026-04-07","ACTUAL",{"date":38,"type":36},"2024-03-01",{"date":40,"type":21},"2037-12-31",{"name":42,"class":43},"University of Salerno","OTHER","Low-Flow, Low-Gradient Aortic Stenosis"]