[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"low-vision-blindness\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:low-vision-blindness":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100298518","health-education-vs-meditation-in-irreversible-age-related-vision-loss-patients-and-their-caregivers-100298518",false,"NCT03166072","Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers","Inclusion Criteria:\n\n* Patients with irreversible age-related vision loss (IARVL) and have ongoing significant disability and\u002For their caregivers who agree to consent.\n* IARVL patients between age 60 to 85 years or caregivers between 18 to 85 years.\n* Deemed competent to provide individual consent to participate.\n* Speak and understand English without requirement for interpretation or assistance.\n* Have no significant self-reported or physician diagnosed mental health disorder other than depressive and\u002For anxiety symptoms.\n* Have either a minimum of CES-D 20-item scale score of 16 OR a minimum of 8 on the Hospital Anxiety Scale (HADS-A) 7-item sub-scale.\n* Have sufficient hearing to be able to follow verbal instructions\n* Ability to sit independently without physical discomfort for 30 minutes.\n* Willing and able to attend, via Microsoft TEAMS software, the four initial training sessions of MEDITATION or HEP and at least 6 follow-up sessions.\n* Willing to dedicate 33 minutes per day to their assigned home practice.\n\nExclusion Criteria:\n\n* Inability to provide informed consent.\n* Dementia as defined by MoCA \\\u003C 21.\n* Have significant suicidal ideation as per self-report (CES-D = 3 on item question 14 and\u002For 15).\n* Have severe depression CES-D ≥ 24.\n* Participating in other similar studies.\n* Have a lifetime diagnosis of self-reported other mental disorders, including bipolar I or II disorder, primary psychotic disorder (schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder).\n* Self-reported substance abuse or dependence within the past 3 months.\n* Have an acutely unstable medical illnesses, including delirium or acute cerebrovascular or cardiovascular events within the last 6 months.\n* Have a terminal medical diagnosis with prognosis of less than 12 months.\n* Having any planned changes to mood-altering medications at the time of enrollment for the next 12 weeks.","ALL","18 Years","85 Years",{"count":19,"type":20},150,"ESTIMATED","INTERVENTIONAL",[23],"NA","Investigators aim to assess the feasibility of delivering two augmentation interventions, Meditation and a Health Enhancement Program, for potentially enhancing the quality of life and mental health of Irreversible Age-Related Vision Loss (IARVL) patients and\u002For their caregivers.",[26,27],"Low Vision, One Eye, Unspecified Eye","Low Vision Blindness",[29,30,31,32,33],"Irreversible age-related vision loss","Randomized controlled trial","Meditation","Pilot study","Quality of life","NOT_YET_RECRUITING","2026-01-30",{"date":37,"type":38},"2026-02-03","ACTUAL",{"date":40,"type":20},"2026-04-20",{"date":42,"type":20},"2027-12-20",{"name":44,"class":45},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":15,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100441464","development-of-a-multi-sensory-rehabilitation-program-for-people-with-ultra-low-vision-100441464","NCT05028712","Development of a Multi-sensory Rehabilitation Program for People With Ultra Low Vision","Inclusion Criteria:\n\n* People with ultra low vision (visual acuity ≤20\u002F1600)\n\nExclusion Criteria:\n\n* \\\u003C12 years of age\n* dependent on sighted guide\n* cognitive impairment","12 Years","99 Years",{"count":56,"type":20},36,[23],"This research is aimed to address one of the big gaps in the current vision rehabilitation protocols for people with profound visual impairment by evaluating a multisensory approach. There are a growing number of clinical trials that recruit people with end-stage eye diseases and the rehabilitation plan following various treatments is not clear. It is important to address this in order to maximize the efficacy of such treatments and to improve the quality of life in people with profound visual impairment.",[27,60,61,62],"Visual Impairment","Quality of Life","Functional Visual Loss",[64,65,66],"ultra low vision rehabilitation","multi sensory","functional vision assessment","RECRUITING","2025-12-04",{"date":70,"type":38},"2025-12-11",{"date":72,"type":38},"2024-03-08",{"date":74,"type":20},"2026-07",{"name":76,"class":45},"State University of New York College of Optometry"]