[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"low-vision-one-eye-unspecified-eye\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:low-vision-one-eye-unspecified-eye":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100298518","health-education-vs-meditation-in-irreversible-age-related-vision-loss-patients-and-their-caregivers-100298518",false,"NCT03166072","Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers","Inclusion Criteria:\n\n* Patients with irreversible age-related vision loss (IARVL) and have ongoing significant disability and\u002For their caregivers who agree to consent.\n* IARVL patients between age 60 to 85 years or caregivers between 18 to 85 years.\n* Deemed competent to provide individual consent to participate.\n* Speak and understand English without requirement for interpretation or assistance.\n* Have no significant self-reported or physician diagnosed mental health disorder other than depressive and\u002For anxiety symptoms.\n* Have either a minimum of CES-D 20-item scale score of 16 OR a minimum of 8 on the Hospital Anxiety Scale (HADS-A) 7-item sub-scale.\n* Have sufficient hearing to be able to follow verbal instructions\n* Ability to sit independently without physical discomfort for 30 minutes.\n* Willing and able to attend, via Microsoft TEAMS software, the four initial training sessions of MEDITATION or HEP and at least 6 follow-up sessions.\n* Willing to dedicate 33 minutes per day to their assigned home practice.\n\nExclusion Criteria:\n\n* Inability to provide informed consent.\n* Dementia as defined by MoCA \\\u003C 21.\n* Have significant suicidal ideation as per self-report (CES-D = 3 on item question 14 and\u002For 15).\n* Have severe depression CES-D ≥ 24.\n* Participating in other similar studies.\n* Have a lifetime diagnosis of self-reported other mental disorders, including bipolar I or II disorder, primary psychotic disorder (schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder).\n* Self-reported substance abuse or dependence within the past 3 months.\n* Have an acutely unstable medical illnesses, including delirium or acute cerebrovascular or cardiovascular events within the last 6 months.\n* Have a terminal medical diagnosis with prognosis of less than 12 months.\n* Having any planned changes to mood-altering medications at the time of enrollment for the next 12 weeks.","ALL","18 Years","85 Years",{"count":19,"type":20},150,"ESTIMATED","INTERVENTIONAL",[23],"NA","Investigators aim to assess the feasibility of delivering two augmentation interventions, Meditation and a Health Enhancement Program, for potentially enhancing the quality of life and mental health of Irreversible Age-Related Vision Loss (IARVL) patients and\u002For their caregivers.",[26,27],"Low Vision, One Eye, Unspecified Eye","Low Vision Blindness",[29,30,31,32,33],"Irreversible age-related vision loss","Randomized controlled trial","Meditation","Pilot study","Quality of life","NOT_YET_RECRUITING","2026-01-30",{"date":37,"type":38},"2026-02-03","ACTUAL",{"date":40,"type":20},"2026-04-20",{"date":42,"type":20},"2027-12-20",{"name":44,"class":45},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER"]