[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lower-extremity-injuries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lower-extremity-injuries":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100570659","effect-of-custom-dynamic-orthoses-on-forefoot-loading-100570659",false,"NCT06710119","Effect of Custom Dynamic Orthoses on Forefoot Loading","LoadsolCP","Patient Inclusion criteria\n\n* Ages: 18-65\n* Sustained a function limiting injury below the knee, requiring a carbon fiber custom dynamic orthosis\n* Shoe size between women's 8 and 13.5 or men's 6.5 and 13\n* Any of the following: weakness of ankle plantarflexors (\\\u003C4\u002F5 on MMT), limited pain free ankle motion (DF\\\u003C10deg or PF\\\u003C20deg), mechanical pain with loading onto hindfoot\u002Fmidfoot\u002Fforefoot (\\>4\u002F10 on verbal numeric pain rating scale), ankle or hindfoot fusion, candidate for ankle or hindfoot fusion, candidate for amputation secondary to ankle\u002Ffoot impairment\n* Ability to walk 25 feet without using a cane or crutch\n* Ability to walk at a slow to moderate pace\n* Able to read and write in English and provide written informed consent\n\nPatient Exclusion criteria\n\n* Pain \\> 9\u002F10 while walking\n* Ankle weakness as a result of spinal cord injury or central nervous system pathology\n* AFO or CDO prescription that includes a knee brace or goes up to thigh\n* Medical or psychological conditions that would preclude functional testing (ex. severe traumatic brain injury, heart condition, clotting disorder, lung condition, stroke, vestibular disorder)\n* Nerve, muscle, bone, or other condition limiting function of the contralateral extremity\n* BMI greater than 40\n* Visual or hearing impairment that limit walking ability or limit the ability to comply with instructions given during testing\n* Pregnancy","ALL","18 Years","65 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The proposed study is designed to evaluate how foot loading changes during initial accommodation to a carbon fiber custom dynamic orthosis (CDO), after targeted training with or without visual feedback of foot loading, and after take-home use of the CDO. This study will quantify initial offloading associated with CDO use and determine if visual feedback of foot loading and additional take-home use of the CDO can further reduce forces, as orthotists work to provide CDOs to patients.",[27],"Lower Extremity Injuries",[29,30,31,32,33,34],"Gait Analysis","Ankle Foot Orthosis","Carbon Fiber","Biomechanics","Visual Feedback","Foot Loading","RECRUITING","2025-12-29",{"date":38,"type":39},"2025-12-31","ACTUAL",{"date":41,"type":39},"2025-06-18",{"date":43,"type":21},"2027-12-31",{"name":45,"class":46},"University of Iowa","OTHER",2]