[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lower-extremity-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lower-extremity-injury":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100636465","cohort-study-of-ppp-injections-for-athletes-with-muscle-injury-100636465",false,"NCT07566039","Cohort Study of PPP Injections for Athletes With Muscle Injury","Prospective Cohort Study of Athletes Following an Injection of Platelet-Poor Plasma Into an Acute Muscle Injury","Inclusion Criteria:\n\n* Age between 18 and 45 years\n* Diagnosis of a muscle strain in the lower extremities, including but not limited to hamstring, quadriceps, and gastrocnemius\n* Injury occurred within 10 days of the initial clinical evaluation\n* Injury occurred while engaging in athletic or sporting activities\n* Participants must be willing to undergo prescribed physical therapy\n* Participants have agreed to standard-of-care management for their injury, which may include ultrasound-guided aspiration with or without a platelet-poor plasma injection\n\nExclusion Criteria:\n\n* Previous injection at the injury site.\n* Pregnant or breastfeeding women, or women who may become pregnant during the study duration\n* Injuries resulting from puncture or crush trauma\n* Injuries occurring more than 10 days prior to the injection date\n* Injuries not caused by athletic or sporting activity\n* Previous muscle injury in the same muscle group within 6 months","ALL","18 Years","45 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","The investigators hypothesize that a single injection of platelet-poor plasma (PPP) into an acute muscle injury will significantly improve local muscle regeneration and patient outcomes compared to the standard of care using only ultrasound-guided hematoma aspiration. Muscle regeneration will be assessed through quantitative MRI analysis. The investigators anticipate that PPP injections will lead to a measurable reduction in scar tissue and an increase in regenerated muscle tissue at the injury site over a six-month period.",[27],"Lower Extremity Injury",[29,30,31,32,33],"Lower extremity injury","PPP injection","Platelet Poor Plasma injection","Athlete","muscle injury","NOT_YET_RECRUITING","2026-05-04",{"date":37,"type":38},"2026-05-06","ACTUAL",{"date":40,"type":21},"2026-05-01",{"date":42,"type":21},"2030-12-31",{"name":44,"class":45},"University of Colorado, Denver","OTHER",3,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":17,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100609785","dance-mental-health-app-100609785","NCT07219095","Dance Mental Health App","Use of a Mental Health App in the Recovery of Adolescent Dancers From a Lower Extremity Injury: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Provision of informed consent (adult participant), or consent of parent\u002Flegal guardian in conjunction with adolescent assent (minor participant)\n2. 13 to 18 years of age\n3. Endorses dance as their primary sport, or participates 3 days per week or greater in dance prior to injury\n4. Stated willingness to comply with all study procedures including the intervention regimen and availability for the duration of the study\n5. Access to a device with which the SuperBetter app can be downloaded and used\n\nExclusion Criteria:\n\n1. Dance is not a primary sport or less than 3 days per week spent dancing prior to injury (skater, gymnast, other sport)\n2. Requiring surgery or prior surgery for the injury being treated\n3. Injury outside of the leg below the knee\n4. Known eating disorder or bone density issue (documented abnormal Z score and\u002For eating disorder diagnosis upon review of the medical chart)\n5. Verbalized plans to not return to dance after recovery from the injury","13 Years",{"count":56,"type":21},50,[24],"This project aims to enhance self-compassion in adolescent dancers recovering from a foot and ankle injury by incorporating the use of a mental health intervention app using gamified design during their recovery.",[60,61,27],"Ankle Injury","Foot Injury",[63,64],"dance","self-compassion","RECRUITING","2025-10-16",{"date":68,"type":38},"2025-10-21",{"date":70,"type":21},"2025-11-15",{"date":72,"type":21},"2029-11-15",{"name":74,"class":45},"University of California, San Diego",1]