[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lower-limb-spasticity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lower-limb-spasticity":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100627384","trial-to-test-the-effectiveness-of-vibrotactile-stimulation-for-lower-limb-spasticity-100627384",false,"NCT07447934","Trial to Test the Effectiveness of Vibrotactile Stimulation for Lower Limb Spasticity","Vibrotactile Stimulation for Lower Limb Spasticity","Inclusion Criteria:\n\n* ≥6 months following neurologic diagnosis leading to spasticity\n* Modified Ashworth Scale (MAS) score of 3 or lower on ankle plantar flexor.\n* Ability to stand (with or without assistance) and lie supine.\n* Able to understand and comply with study procedures.\n\nExclusion Criteria:\n\n* Uncontrolled systemic illness or serious medical conditions that could interfere with study procedures.\n* Previous surgery to treat spasticity in the affected lower limb.\n* Prior Botulinum Toxin (BoNT) therapy in the target limb within 4 months.\n* Unstable medication regimens for spasmolysis or muscle relaxation.\n* Participation in tone-related treatments (e.g., physiotherapy, TENS, acupuncture) within 4 weeks prior to baseline. If ongoing treatment started more than 4 weeks before baseline, it should remain consistent throughout the study","ALL","18 Years","85 Years",{"count":20,"type":21},25,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find out if Vibrotactile Stimulation (VTS) can help improve mobility and reduce spasticity (muscle stiffness) in people with lower limb spasticity. The study will also look at how VTS affects walking speed. The main questions it aims to answer are:\n\n* Which areas of the body are the best for applying VTS?\n* Does VTS help improve walking speed in people with lower limb spasticity?\n\nParticipants will:\n\n* Receive 15 minutes of VTS treatment on different parts of the body\n* Use the VTS device for 60 minutes during supervised lab sessions and at home (at rest and while walking)\n* Complete a daily log of how much time the device was used for and note any issues or difficulties the participant experience\n* Complete assessments after the treatment to measure change in mobility\n* Complete surveys about how comfortable the device is to use",[27],"Lower Limb Spasticity",[29,30,31,32,33,34,35,36,37,38],"mobility","lower limb","spasticity","walking endurance","home device","quality of life","vts","LLS","gait","stroke","RECRUITING","2026-06-15",{"date":42,"type":43},"2026-06-17","ACTUAL",{"date":45,"type":43},"2026-04-30",{"date":47,"type":21},"2027-10-31",{"name":49,"class":50},"Weill Medical College of Cornell University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":4},"100633173","effect-of-extracorporeal-shock-wave-therapy-on-spasticity-and-mobility-in-stroke-patients-100633173","NCT07523243","Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients","Efficacy of Extracorporeal Shock Wave Therapy on Spasticity, Mobility, Motor Function, and Health-Related Quality of Life in Stroke Survivors: A Prospective Randomized Sham-Controlled Trial","ESWT-STROKE","Inclusion Criteria:\n\n* Adults aged 18-65 years\n* Diagnosed with ischemic or hemorrhagic stroke at least 3 months prior to enrollment Presence of lower extremity spasticity with a Modified Ashworth Scale (MAS) score ≥1+\n* Ability to walk independently with or without assistive devices\n* Ability to understand and follow instructions for exercise interventions and assessments\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Receipt of botulinum toxin injection in the affected lower limb within the last 3 months\n* Severe cognitive impairment preventing participation in assessments\n* Presence of fixed joint contractures limiting range of motion\n* Orthopedic or musculoskeletal disorders affecting lower limb function (e.g., fracture, severe osteoarthritis)\n* Uncontrolled cardiovascular, respiratory, or systemic disease contraindicating exercise\n* Participation in another interventional clinical trial\n* Any condition judged by the investigator to interfere with participation or safety","65 Years",{"count":62,"type":21},85,[24],"This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke. Spasticity is a common complication after stroke and can negatively affect walking ability, mobility, and quality of life.\n\nParticipants will be randomly assigned to one of two groups. Both groups will receive a standard physiotherapy and rehabilitation program. In addition, the intervention group will receive ESWT applied to the lower limb muscles, while the control group will receive a sham (placebo) ESWT application.\n\nThe treatment program will be conducted three times per week for four weeks. Clinical assessments will be performed at baseline, after treatment, and during follow-up.\n\nThe main outcomes of the study include muscle tone (spasticity), walking performance, motor function, and quality of life. The results of this study may help improve rehabilitation strategies and provide evidence for the use of ESWT in stroke patients.",[66,67,27],"Stroke","Post-Stroke Spasticity",[69,70,71,72,73],"Extracorporeal Shock Wave","ESWT Stroke Rehabilitation","Mobility Fugl-Meyer","Quality of Life","Spasticity","NOT_YET_RECRUITING","2026-04-09",{"date":77,"type":43},"2026-04-14",{"date":79,"type":21},"2026-04",{"date":81,"type":21},"2026-06-20",{"name":83,"class":50},"Istanbul Medipol University Hospital"]