[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lower-urinary-tract-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lower-urinary-tract-dysfunction":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":48},"100625621","ambulatory-long-length-urodynamics-evaluation-100625621",false,"NCT07425015","Ambulatory Long Length URodynamics Evaluation","ALLURE","Inclusion Criteria:\n\n1. Male or female patient must be ≥ 22 years of age.\n2. Patient is a candidate for UDS per standard of care.\n3. Patient is able to provide informed consent.\n\nExclusion Criteria:\n\n1. Patient has one or more symptoms indicative of a urinary tract infection (UTI) (i.e., fever, costovertebral angle pain or tenderness, suprapubic tenderness, worsening urinary frequency, worsening urgency, and\u002For dysuria).\n2. Patient has a history of recurrent UTIs (≥ 3 episodes in previous 12 months).\n3. Patient has used antibiotics within the past 7 days from the baseline\u002Fscreening visit.\n4. Patient diagnosed with neurogenic LUTD (i.e., one or more of these conditions: normal-pressure hydrocephalus, cerebral palsy, spinal cord injuries, traumatic brain injury, stroke, Parkinson's disease, multiple sclerosis, meningomyelocele, spina bifida, dementia, Guillain-Barre syndrome, and tumors involving the central nervous systems or spine).\n5. Patient diagnosed with interstitial cystitis (IC), bladder pain syndrome, painful bladder syndrome or any etiology of chronic pelvic pain syndrome (CPPS).\n6. Patient with a urostomy.\n7. Patient with a colostomy.\n8. Patient has an atypical anatomic structural variation or has had a previous surgical intervention that has permanently changed structural anatomy anywhere along their lower urinary tract (urethra, pelvic floor, urethral sphincter, and\u002For bladder wall) that the principal investigator deems might compromise the placement or retention of the Glean sensors during the study (e.g., strictures).\n9. Patient has a Pelvic Organ Prolapse Quantification (POP-Q) of Grade III or higher (i.e., most distal portion of the prolapse protrudes more than 1 centimeter below the hymen).\n10. Patient with any abnormal or concerning rectal conditions such as ongoing anal fissures, rectocele, fistula, active herpes, or active yeast infections.\n11. Patient has a known inability to void.\n12. Patient has a previous history of radiation leading to bleeding (e.g., hemorrhagic radiation cystitis).\n13. Patient is pregnant (as confirmed by urine pregnancy test or medical history) or breastfeeding, pregnant within the past 6 months, or intending to become pregnant during the study period.\n14. Patients who may not be able to independently use a smart device.\n15. Subjects who, at the principal investigator's determination, would not be appropriate for this study.","ALL","22 Years",{"count":19,"type":20},101,"ESTIMATED","INTERVENTIONAL",[23],"NA","A prospective, open-label, single arm interventional trial evaluating the safety and performance of the in-clinic and extended monitoring of the lower urinary tract using the Glean Urodynamics System.",[26,27,28,29,30,31,32],"Urology","Urinary Bladder, Overactive","Benign Prostatic Hyperplasia","Urodynamics","Home Monitoring","Urinary Incontinence (UI)","Lower Urinary Tract Dysfunction",[34,35,36],"Bright Uro","Glean Urodynamics System","Uroflowmetry","RECRUITING","2026-04-13",{"date":40,"type":41},"2026-04-15","ACTUAL",{"date":43,"type":41},"2026-02-17",{"date":45,"type":20},"2027-06",{"name":34,"class":47},"INDUSTRY",7,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":63,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":77},"100602704","video-game-based-balance-training-in-children-with-lower-urinary-tract-dysfunction-100602704","NCT07126977","Video Game-Based Balance Training in Children With Lower Urinary Tract Dysfunction","The Effect of Video Game-Based Balance Exercises Added to Standard Rehabilitation on Clinical Symptoms and Pelvic Floor Muscle Functions in Children With Lower Urinary Tract Dysfunction","Inclusion Criteria:\n\n* Being between 5 and 12 years of age\n* Having a diagnosis of \"Lower Urinary Tract Dysfunction\" made by a pediatric urologist according to the criteria defined by the ICCS\n* Voluntary participation of both the parent and the child in the study\n\nExclusion Criteria:\n\n* Having any neurologically based condition\n* Presence of any condition in the parent or child that affects the ability to respond to the assessment tools (e.g., intellectual disability, developmental delay, cognitive problems)\n* Having any physical impairment (orthopedic, structural, etc.) that prevents the use of Wii-Fit\n* Presence of malformations or anatomical anomalies in the urinary tract system\n* History of urological surgery\n* Having constipation and\u002For fecal incontinence\n* Previous participation in pelvic floor muscle rehabilitation\n* Regular use of medication","5 Years","12 Years",{"count":59,"type":20},30,[23],"This study aims to investigate the effects of video game-based balance exercises, in addition to standard treatment, in children aged 5-12 years with lower urinary tract dysfunction (LUTD). The single-center study will include 30 children who will be randomly assigned to an experimental group (video game-based balance exercises + standard treatment) or a control group (standard treatment only). Children in the experimental group will play selected balance games using the Wii console and Wii Balance Board twice a week for 8 weeks.\n\nAll participants will receive the standard program consisting of urotherapy, diaphragmatic breathing exercises, biofeedback-assisted pelvic floor muscle training, and functional exercises. Outcomes will be assessed using a Bladder Diary, uroflowmetry, ultrasonography for post-void residual urine, pelvic floor muscle activity with EMG, the Dysfunctional Voiding and Incontinence Symptoms Score Questionnaire(DVISS), quality of life with the Pediatric Incontinence Quality of Life Questionnaire (PinQ), balance tests, the McGill Core Endurance Test, and the Physical Activity Enjoyment Scale.",[32],[64,65,66],"pelvic floor","lower urinary tract dysfunction","rehabilitation","2025-09-01",{"date":69,"type":41},"2025-09-08",{"date":71,"type":41},"2025-06-15",{"date":73,"type":20},"2026-02",{"name":75,"class":76},"Bahçeşehir University","OTHER",1,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":21,"phases":89,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":77},"100592993","micturition-desire-relaxation-training-device-for-lower-urinary-tract-dysfunction-in-children-100592993","NCT07000656","Micturition Desire-Relaxation Training Device for Lower Urinary Tract Dysfunction in Children","Prospective Evaluation of Micturition Desire-Relaxation Training Device for Treating Lower Urinary Tract Dysfunction in Children: A Randomized Controlled Pilot Study","ICCS，LUTD，PNE","Inclusion Criteria:\n\n1. Diagnosis according to the ICCS criteria:\n\n   For nocturnal enuresis:\n\n   At least one episode of involuntary nighttime urination per month for more than 3 months.\n\n   No abnormalities in routine urinalysis. No period of bedwetting-free days lasting more than 6 months, except for organic diseases.\n\n   For daytime urinary incontinence:\n\n   At least one episode of intermittent urinary leakage during wakefulness per month for more than 3 months.\n\n   No anatomical or neurological causes of urinary incontinence.\n\n   For urinary frequency:\n\n   The child experiences only urinary frequency and urgency, occurring during the day and before sleep, with intervals ranging from a few minutes to 1 hour. Each urination involves a small volume, less than 50% of the estimated bladder capacity \\[EBC (mL) = 30 + (age × 30)\\], typically less than 30 mL, sometimes just a few drops, while total daily urine volume remains within normal limits. When the child is engaged in play or focused, the intervals between urination are extended, and urinary frequency symptoms disappear after falling asleep.\n2. Age: 5 to 18 years (inclusive), regardless of gender.\n3. Voluntary participation: The child and their guardian must voluntarily participate in the trial and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Exclude enuresis caused by urinary tract infections, pinworms, myelitis, spinal cord injuries, epilepsy, cerebral developmental disorders, diabetes, and other neurological, urinary, or endocrine diseases, as well as transient enuresis due to excessive activity, mental fatigue, or excessive fluid intake before bedtime.\n2. Exclude conditions causing urinary frequency such as neurogenic bladder, urinary tract infections, urethral syndrome, hypercalciuria, or metabolic diseases.\n3. Patients who have participated in or are currently participating in other clinical trials within the past month.\n4. Patients deemed unsuitable for participation in the clinical trial by the investigator.","18 Years",{"count":88,"type":20},200,[23],"Urine storage and voiding are fundamental physiological processes. In clinical settings, many cases of lower urinary tract dysfunction (LUTD) are closely associated with abnormal conditioned reflexes formed in the central nervous system during the urine storage or voiding phases. Relaxation, as a core physiological and psychological state, has been shown to promote effective urine storage and facilitate smooth voiding. By repeatedly training individuals to establish a new conditioned reflex linking the sensation of urinary urgency with a state of relaxation, it may be possible to improve bladder storage capacity and voiding function. Based on this concept, the investigators have developed the world's first Micturition Desire-Relaxation Training Device (Chinese Patent No.: ZL 2020 1 0397789.4). This study aims to evaluate the clinical efficacy of this device in treating LUTD in children.",[92,93,32,94],"Daytime Urinary Incontinence","Urinary Frequency","Primary Nocturnal Enuresis","2025-06-02",{"date":97,"type":41},"2025-06-05",{"date":99,"type":41},"2024-11-20",{"date":101,"type":20},"2026-05-31",{"name":103,"class":76},"Shanghai Children's Medical Center"]