[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lower-urinary-tract-symptoms-luts\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lower-urinary-tract-symptoms-luts":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,50,81,108,132,159,190,217,248],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100636760","thulium-laser-enucleation-with-bladder-neck-incision-for-small-volume-benign-prostatic-hyperplasia-100636760",false,"NCT07569874","Thulium Laser Enucleation With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia","Thulium Laser Enucleation of the Prostate Combined With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia: A Multicentre, Randomized, Single-Blind, Controlled Trial","ThuLEP-BNI","Inclusion Criteria:\n\n* Male patients aged 40-80 years.\n* Diagnosis of benign prostatic hyperplasia (BPH) and scheduled to undergo surgical treatment.\n* International Prostate Symptom Score (IPSS) of at least 12, maximum urinary flow rate of no more than 15 mL\u002Fs, with a voided volume greater than 150 mL.\n* Prostate volume of less than 30 mL measured by transrectal ultrasound (TRUS), calculated as length × width × height × 0.52.\n* Ability, as assessed by the investigator, to understand the study requirements and complete the scheduled treatment, follow-up visits, and study-related assessments.\n\nExclusion Criteria:\n\n* Inability or refusal to provide written informed consent, or inability to comply with the required follow-up schedule.\n* Prostate-specific antigen (PSA) level of 10 ng\u002FmL or higher, unless prostate cancer has been excluded by biopsy.\n* Confirmed or suspected prostate or bladder malignancy.\n* Pre-existing bladder neck contracture or urethral stricture before surgery.\n* Known coagulation disorder or abnormal coagulation function.\n* Neurogenic bladder or detrusor underactivity that may affect bladder or urethral sphincter function.\n* Benign prostatic hyperplasia (BPH) complicated by acute urinary tract infection, acute prostatitis, or bacterial prostatitis.\n* History of prostate surgery, urethral stricture, or neurogenic bladder.\n* History of prostate cancer or pelvic radiotherapy.\n* Severe cardiovascular disease, pulmonary disease, or other systemic disease that, in the investigator's judgment, would make the patient unable to tolerate surgery.\n* Participation in another clinical trial related to benign prostatic hyperplasia (BPH) within 3 months before enrolment.\n* Any other condition that, in the investigator's opinion, makes the patient unsuitable for participation in this study.","MALE","40 Years","80 Years",{"count":21,"type":22},615,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will evaluate the safety and effectiveness of thulium laser enucleation of the prostate combined with bladder neck incision in men with small-volume benign prostatic hyperplasia (BPH). Small-volume BPH may still cause significant bladder outlet obstruction and bothersome lower urinary tract symptoms, and the optimal surgical treatment for these patients remains uncertain.\n\nIn this multicenter, randomized, single-blind, controlled trial, 426 eligible men aged 40 to 80 years will be assigned in a 1:1:1 ratio to one of three groups: thulium laser enucleation of the prostate combined with bladder neck incision, thulium laser enucleation alone, or transurethral resection of the prostate. The main goal is to compare the incidence of bladder neck contracture at 6 months after surgery. Other outcomes include symptom improvement, urinary flow, pain score, sexual function, and safety outcomes during follow-up.",[28,29,30],"Benign Prostatic Hyperplasia","Bladder Outlet Obstruction","Lower Urinary Tract Symptoms (LUTS)",[32,33,34,35,36],"Small-Volume Benign Prostatic Hyperplasia","Thulium Laser Enucleation of the Prostate","Bladder Neck Incision","Bladder Neck Contracture","Lower Urinary Tract Symptoms","NOT_YET_RECRUITING","2026-06-16",{"date":40,"type":41},"2026-06-18","ACTUAL",{"date":43,"type":22},"2026-07",{"date":45,"type":22},"2028-06",{"name":47,"class":48},"Chinese PLA General Hospital","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100637554","portuguese-mobile-app-version-of-the-iciq-bladder-diary-for-adults-with-urinary-symptoms-development-and-feasibility-study-100637554","NCT07602413","Portuguese Mobile App Version of the ICIQ Bladder Diary for Adults With Urinary Symptoms: Development and Feasibility Study","Development and Feasibility of the Portuguese Version of the ICIQ-bladder Diary as a Mobile Application","Inclusion Criteria\n\n* Adults aged 18 years or older\n* Diagnosis of overactive bladder and\u002For urinary incontinence for at least 6 months\n* Previous experience completing a paper bladder diary\n* Own and regularly use a smartphone\n* Able to understand and use the My São João App and the Diário da Bexiga VD mobile application\n* Able and willing to provide informed consent\n\nExclusion Criteria\n\n* Unable to understand, read, speak, or write Portuguese\n* No regular access to the internet during the study period\n* Unable to use a smartphone application independently","ALL","18 Years",{"count":60,"type":22},40,"1 Month","OBSERVATIONAL","The goal of this clinical trial is to evaluate a mobile app version of the International Consultation on Incontinence Questionnaire Bladder Diary (ICIQ-Bladder Diary) in Portuguese adults with urinary symptoms. The study aims to learn whether an electronic bladder diary is feasible, easy to use, and well accepted by participants and physicians.\n\nThe main questions it aims to answer are:\n\nIs the mobile app feasible, based on the percentage of participants who completely fill in the diary over 1 month? Do participants consider the app to be high quality and easy to use? Do participants and physicians prefer the electronic diary over paper formats?\n\nParticipants will:\n\nUse the mobile app version of the ICIQ-Bladder Diary for 1 month; Complete questionnaires about app quality, usability, and preference, including the User Mobile App Rating Scale (uMARS).\n\nSix rehabilitation physicians will review the completed diaries and answer questions about ease of interpretation and preferred diary format.\n\nThe investigators expect the app to be feasible and well accepted by both participants and physicians. If successful, the app may support wider use of electronic bladder diaries in clinical practice in Portugal.",[30],[66,67,68,69,70],"Bladder diary","incontinence","smartphone","mobile app","electronic diary","2026-05-18",{"date":73,"type":41},"2026-05-22",{"date":75,"type":22},"2026-05-25",{"date":77,"type":22},"2026-08-31",{"name":79,"class":80},"Unidade Local de Saúde São João","OTHER_GOV",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":57,"minAge":4,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":23,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":107},"100640507","essential-oils-for-urinary-symptoms-in-multiple-sclerosis-patients-100640507","NCT07599189","Essential Oils for Urinary Symptoms in Multiple Sclerosis Patients","Efficacy and Safety of Essential Oil Aromatherapy on Neurogenic Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis: A Randomized Single-Blind Placebo-Controlled Clinical Trial.","AROMA-MS","Inclusion Criteria:\n\n* Confirmed diagnosis of Multiple Sclerosis (any form)\n* Documented lower urinary tract symptoms defined by an Overactive Bladder Symptom Score (OABSS) ≥ 3 at screening\n* Age between 18 and 65 years\n* Willing and able to provide written informed consent\n* Capable of performing daily topical self-application of the study oil, or having a caregiver available to assist throughout the study period\n\nExclusion Criteria:\n\n* Active urinary tract infection confirmed by urine culture at screening\n* Pre-existing urological condition unrelated to Multiple Sclerosis (e.g., bladder cancer, benign prostatic hyperplasia, or interstitial cystitis)\n* Known allergy or hypersensitivity to essential oils, apricot kernel oil, lavender, or rosemary\n* Active skin lesions, wounds, or dermatological conditions on the lower abdomen at the intended site of application\n* Pregnancy, breastfeeding, or planning to become pregnant during the study period\n* Significant cognitive impairment preventing understanding of study procedures or completion of questionnaires\n* Current use of an indwelling urinary catheter or practice of intermittent self-catheterization",{"count":90,"type":22},60,[25],"The goal of this clinical trial is to learn if essential oil aromatherapy works to improve urinary symptoms in adults with multiple sclerosis. It will also learn about the safety of essential oil use in this population.\n\nThe main questions it aims to answer are:\n\n* Does essential oil aromatherapy reduce urinary urgency, frequency, and incontinence episodes in participants with multiple sclerosis?\n* What medical problems do participants have when using essential oil aromatherapy?\n\nResearchers will compare essential oil aromatherapy to a placebo (a look-alike neutral oil with no therapeutic properties) to see if essential oil aromatherapy works to improve urinary symptoms in multiple sclerosis patients.\n\nParticipants will:\n\n* Use essential oil aromatherapy or a placebo oil every day for 6 weeks\n* Complete a urinary symptom scales to record the frequency, urgency, and any leakage episodes each day\n* Fill out quality of life questionnaires at the beginning and end of the study",[94,95,96,97,30],"Multiple Sclerosis (MS)","Neurogenic Bladder Disorder","Urinary Incontinence (UI)","Urinary Urgency","2026-05-16",{"date":100,"type":41},"2026-05-20",{"date":102,"type":22},"2026-09",{"date":104,"type":22},"2027-03",{"name":106,"class":48},"University of Oran 1",2,{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":114,"sex":57,"minAge":58,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":23,"phases":118,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":128,"locationsCount":131},"100630248","establishing-normative-urodynamics-parameters-for-the-glean-urodynamics-system-in-healthy-adults-100630248","NCT07485205","Establishing Normative Urodynamics Parameters for the Glean Urodynamics System in Healthy Adults","Inclusion Criteria:\n\n1. Healthy male and female adults ages 18 to 45 years.\n2. Patient is able to read, write, and communicate in English.\n3. Patient is able to provide informed consent.\n4. Patient owns, can independently operate, and is willing to use a smart device for study data collection purposes\n\nExclusion Criteria:\n\n1. Patient with any prior pregnancy (gravida ≥1), is currently pregnant (as confirmed by urine pregnancy test or medical history), or intends to become pregnant during the study period.\n2. Patient has one or more symptoms indicative of a symptomatic urinary tract infection (UTI) (i.e., fever, costovertebral angle pain or tenderness, suprapubic tenderness, worsening urinary frequency, worsening urgency, and\u002For dysuria).\n3. Patient has a known history of urological conditions (e.g., recurrent UTIs, incontinence, symptomatic benign prostatic hyperplasia, neurogenic bladder, interstitial cystitis, urinary retention, any genitourinary cancer).\n4. Patient has a known history of neurological conditions that can affect central nervous system function.\n5. Patients with a current or prior diagnosis of diabetes mellitus (Type 1 or Type 2).\n6. Patient is currently taking medications that may affect urological functions (e.g., diuretics, anticholinergics, alpha-blockers).\n7. Patient has abnormal urinary habits if one or more of the following bladder events are reported on any day of the 3-day bladder diary: urinary frequency ≥ 8 times\u002Fday, ≥ 1 nocturia episode, ≥ 1 leak event, or ≥ 1 urgency event.\n8. Patient has a total score on the Lower Urinary Tract Dysfunction Research Network Symptom Index-10 (LURN SI-10) questionnaire greater than 0; a total score of 1 is acceptable only if the sole positive response is urinary frequency of 4-7 times per day.\n9. Patient has a urostomy and\u002For colostomy.\n10. Patient has an atypical anatomic structural variation or has had a previous surgical intervention that has permanently changed structural anatomy anywhere along their lower urinary tract (urethra, pelvic floor, urethral sphincter, and\u002For bladder wall) that the principal investigator deems might compromise the placement or retention of the Glean sensors during the study (e.g., strictures).\n11. Patient has a Pelvic Organ Prolapse Quantification (POP-Q) of Grade III or higher (i.e., most distal portion of the prolapse protrudes more than 1 centimeter below the hymen).\n12. Patient would not be appropriate for this study as determined by the Principal Investigator.",true,"45 Years",{"count":117,"type":22},72,[25],"A prospective, open-label, single arm interventional trial to establish normative reference ranges for urodynamics parameters in healthy adult participants using using the Glean Urodynamics System.",[30],"RECRUITING","2026-04-17",{"date":124,"type":41},"2026-04-22",{"date":126,"type":41},"2026-03-31",{"date":104,"type":22},{"name":129,"class":130},"Bright Uro","INDUSTRY",3,{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":138,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":17,"minAge":140,"maxAge":4,"enrollmentInfo":141,"targetDuration":4,"studyType":23,"phases":143,"briefSummary":144,"conditions":145,"keywords":147,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":49},"100633437","concomitant-trans-perineal-prostate-biopsy-and-ablation-bioblation-for-prostate-cancer-100633437","NCT07526675","Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer","Validation of Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Symptomatic (LUTS) Selected Most Probably Low and Intermediate Risk PCa Patients","Bioblation","Inclusion Criteria:\n\n* Patients with severe Lower Urinary Tract Symptoms (LUTS) meeting the following parameters:\n\n  1. IPSS score \\> 20\n  2. Uroflowmetry flow rate \\\u003C 10 ml\u002Fsec\n  3. Post-void residual \\> 150 cc\n* Patients most probably having low to favorable intermediate-risk prostate cancer, defined as:\n\n  1. PSA level between 4 and 20 ng\u002Fml\n  2. MP-MRI showing 3 or fewer focal lesions\n  3. MP-MRI focal lesions measuring \\\u003C 1.5 cm\n* International or visiting patients requiring early return to their home country due to professional or personal commitments, provided they can undergo short-term management and follow-up coordination\n\nExclusion Criteria:\n\n* Patient PSA level \\> 20 ng\u002Fml\n* More than 3 focal lesions on MP-MRI\n* Metastatic prostate cancer\n* History of lower urinary tract surgery (e.g., TURP, Laser, urinary diversions, artificial urinary sphincter)\n* History of pelvic radiation therapy or radical pelvic surgery","18 Months",{"count":142,"type":22},30,[25],"This prospective study aims to validate the clinical outcomes of performing a concomitant trans-perineal prostate biopsy and laser ablation (termed \"Bioblation\") during a single session. The intervention is designed for symptomatic patients presenting with lower urinary tract symptoms (LUTS) who are highly suspected to have low to favorable intermediate-risk prostate cancer. By combining diagnosis and targeted treatment under local anesthesia, this approach seeks to facilitate early relief of severe symptoms and a rapid return to daily activities. Ultimately, the study evaluates whether this combined procedure decreases the patient's exposure to multiple, temporally separated interventions without compromising oncological safety or efficacy.",[146,30,28],"Prostate Cancer",[146,148,138,149,36,28],"Transperineal Laser Ablation","Focal Therapy","2026-04-09",{"date":152,"type":41},"2026-04-13",{"date":154,"type":22},"2026-04-10",{"date":156,"type":22},"2026-04-28",{"name":158,"class":48},"Benha University",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":11,"sex":166,"minAge":58,"maxAge":4,"enrollmentInfo":167,"targetDuration":4,"studyType":23,"phases":169,"briefSummary":170,"conditions":171,"keywords":173,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":107},"100577439","reducing-disparities-in-urinary-control-symptoms-for-minority-women-100577439","NCT06798311","Reducing Disparities in Urinary Control Symptoms for Minority Women","SUPPORT","Inclusion Criteria:\n\n* Age 18 years or older\n* Able to converse in English\n* A response of at least \"somewhat bothered\" by urinary incontinence, urinary frequency or urgency on the UDI\n* Willing to engage in conservative treatment of their UI\u002FLUTS for 16 weeks\n\nExclusion Criteria:\n\n* Anterior or posterior pelvic organ prolapse beyond the hymen or apical prolapse to the hymen\n* Currently taking medications for their UI\u002FLUTS or history of surgical intervention for UI\n* Patients with abnormal PVR and positive urine culture at time of study entry\n* History of recurrent UTIs\n* History of mobility or neurologic disorders that would prevent ability to complete at home physical therapy\n* Planning to start PT within the next 16 weeks","FEMALE",{"count":168,"type":22},80,[25],"The study is designed to address the disparity in available conservative\u002Fbehavioral treatments for UI\u002FLUTS. The program was developed by experts from urogynecology, psychology, and physical therapy then modified based on focus group feedback from racially minoritized women. The study team created a patient-centered, culturally adapted, self-directed, 8-week, home-based module for women with LUTS\u002FUI. The SUPPORT program combines multiple evidence-based conservative treatments for LUTS\u002FUI including cognitive behavioral therapy, behavioral modifications, and home physical therapy exercise. Progression through the home-based program is supported by research staff. This prospective interventional study aims to evaluate the feasibility and acceptability of the SUPPORT program and its impact on patient-centered treatment outcomes, while enabling comparisons across race and ethnicity. This approach will provide a comprehensive understanding of how to effectively deliver self-management strategies for pelvic floor disorders.\n\nAt the start of the 8 week SUPPORT course participants will also be given access to a custom programmed GPT trained on the SUPPORT workbook and given instructions on empathetic communication techniques and assisting patients in performing the SUPPORT exercises as outlined in the program. At the end of 8 weeks patients will fill out a survey assessing the frequency of use and interactions with the LLM.",[96,30,172],"Pelvic Floor Disorder",[174,175,176,177,178,179,180],"cognitive behavioral therapy","self-directed","physical therapy","behavioral modifications","pelvic floor","home-based","health disparities","2026-04-06",{"date":183,"type":41},"2026-04-07",{"date":185,"type":41},"2024-10-28",{"date":187,"type":22},"2027-05",{"name":189,"class":48},"University of Chicago",{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":11,"sex":166,"minAge":58,"maxAge":197,"enrollmentInfo":198,"targetDuration":4,"studyType":23,"phases":200,"briefSummary":201,"conditions":202,"keywords":203,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":107},"100627662","rct-on-running-water-sound-during-urodynamic-100627662","NCT07451548","RCT on Running Water Sound During Urodynamic","Impact of Running Water Sound on Anxiety and Urodynamic Parameters: A Multi-Center Randomized Controlled Trial","Inclusion Criteria:\n\n* Chinese women aged 18-90 years scheduled for urodynamic study.\n* Understand written traditional Chinese.\n* Willing to participate and provide a written informed consent.\n\nExclusion Criteria:\n\n* Patients who refuse to participate or provide written consent.\n* Patients who do not understand or comprehend written traditional Chinese.\n* Patients with severe cognitive impairment or inability to complete the VAS.\n* Patients with known psychiatric conditions that may confound anxiety measurements.\n* Patients with hearing impairments that would prevent perception of the running water sound.","90 Years",{"count":199,"type":22},240,[25],"This study aims to see if listening to recorded running water sounds during a bladder function test (urodynamic study) helps patients feel calmer and makes it easier for them to empty their bladder during the test. Bladder tests can cause anxiety or discomfort, which sometimes affects results. Playing running water sounds may help patients relax and improve their experience, based on earlier research. Participants will be randomly placed into one of two groups. One group will listens to running water sounds during the test while the other group will have the test done in the usual way without additional auditory intervention. Participants rate their anxiety before, during, and after the test using simple scales. Parameters of the test will be recorded for analysis.",[30],[204,205,206,207],"Urodynamics","Anxiety","Running water sound","Maximum flow rate","2026-02-28",{"date":210,"type":41},"2026-03-05",{"date":212,"type":41},"2025-12-01",{"date":214,"type":22},"2027-11-30",{"name":216,"class":80},"Princess Margaret Hospital, Hong Kong",{"id":218,"slug":219,"hasResults":11,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":223,"eligibilityCriteria":224,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":225,"targetDuration":4,"studyType":23,"phases":227,"briefSummary":228,"conditions":229,"keywords":235,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":49},"100626004","predictors-of-trifecta-achievement-after-holep-100626004","NCT07429994","Predictors of Trifecta Achievement After HoLEP","Predictors of Trifecta Achievement After Holmium Laser Enucleation of the Prostate","ReMIUS-BPO","Inclusion Criteria:\n\n* All male patients aged ≥ 40 years who are candidates for surgical treatment for BPO.\n* Ability to provide informed consent, when required.\n\nExclusion Criteria:\n\n* Clinically proven active condition(s) that require another intervention other than BPO surgery, such as lower urinary tract malignancy, urethral stricture, or neurogenic lower urinary tract symptoms.\n* History of previous surgery for BPO, urethral stricture, or prostate cancer.\n* Incomplete baseline or procedural data.",{"count":226,"type":22},604,[25],"Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment option for men experiencing bothersome lower urinary tract symptoms due to an enlarged prostate. Researchers predict that specific participant or operator-dependent conditions before or during HoLEP may influence the trifecta outcome, based on similar studies. Therefore, the aim of this study is to understand what these conditions are. Trifecta success indicates a high-quality surgery based on three essential criteria: the treatment's effectiveness, ease of recovery, and the absence of serious side effects. In this study, trifecta is defined as relief from bothersome symptoms validated by international symptom score questionnaires, no urinary incontinence, and no serious events occurring within three months after HoLEP.",[230,231,232,233,30,234,29],"HoLEP","Trifecta Achievement","Urinary Incontinence Following Surgical Procedure","Clavien Dindo Surgical Complication Scale","Benign Prostatic Enlargement (BPE)",[236,237,238],"HoLEP Trifecta","HoLEP Symptomatic Relief","HoLEP Predictive Factors","2026-02-18",{"date":241,"type":41},"2026-02-24",{"date":243,"type":22},"2026-01-30",{"date":245,"type":22},"2028-07-31",{"name":247,"class":48},"Ondokuz Mayıs University",{"id":249,"slug":250,"hasResults":11,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":254,"eligibilityCriteria":255,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":256,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":258,"conditions":259,"keywords":262,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":4},"100594233","uroflowmetry-curve-types-and-ipss-in-men-with-luts-100594233","NCT07016776","Uroflowmetry Curve Types and IPSS in Men With LUTS","Evaluation of the Association Between Uroflowmetry Curve Patterns and IPSS Domains in Men With Lower Urinary Tract Symptoms","UROFLOW-IPSS","Inclusion Criteria:\n\n* Inclusion Criteria:\n* Male patients aged 40 years or older\n* Presenting with lower urinary tract symptoms (LUTS)\n* Able to complete the IPSS questionnaire\n* Underwent uroflowmetry and serum creatinine testing\n\nExclusion Criteria:\n\n* History of prior prostate surgery\n* Active urinary tract infection\n* Known diagnosis of neurogenic bladder\n* Current use of indwelling urinary catheter",{"count":257,"type":22},250,"This prospective observational study aims to evaluate the relationship between different uroflowmetry curve types and International Prostate Symptom Score (IPSS) domains in men presenting with lower urinary tract symptoms (LUTS). Participants will undergo routine clinical evaluations including uroflowmetry, laboratory assessments, and completion of the IPSS questionnaire.\n\nEach participant will be classified into one of five predefined uroflowmetry curve types (normal\u002Fbell-shaped, plateau, staccato, intermittent, or tower-like). The IPSS will be analyzed both as a total score and as two subdomains: storage and voiding symptoms. Additional data such as age, comorbidities, medication use, prostate volume, eGFR, and QoL score will also be recorded to assess potential correlations and predictive factors for symptom severity.\n\nThe goal of this study is to better understand how objective urodynamic findings correlate with patient-reported symptoms and to inform clinical decision-making in men with LUTS.",[30,260,261],"Benign Prostatic Hyperplasia (BPH)","Voiding Dysfunction",[263,264,265,266,267],"International Prostate Symptom Score (IPSS)","Uroflowmetry","Flow curve pattern","Male urinary symptoms","Prospective observational study","2025-08-30",{"date":270,"type":41},"2025-09-03",{"date":272,"type":22},"2025-09-15",{"date":274,"type":22},"2026-06-15",{"name":276,"class":48},"Tarik Emre Sener"]