[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lumbar-post-laminectomy-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lumbar-post-laminectomy-syndrome":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":37,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":5},"100579522","auriculotherapy-neuroimaging-100579522",false,"NCT06825390","AuriculoTherapy NeuroImaging","Mechanistic Clinical Trial of Auricular Stimulation and Cryogenic Auriculotherapy in Patients With Chronic Low-back Pain, Using Functional Near-infrared Spectroscopy and Magnetic Resonance Imaging","ATNI","Inclusion Criteria:\n\n1. Adult, at least 18 years old\n2. Episodes of chronic low back pain at least daily for at least 6 months, with an average pain score within the last week of 3\u002F10.\n\nExclusion Criteria:\n\n1. active lesions, skin disruptions, or neuropathy of either ear;\n2. recent (\\\u003C1 month) analgesic procedures or surgery;\n3. recent (\\\u003C1 month) start of new analgesic or psychoactive medication (including marijuana, opioids, tramadol, methadone, gabapentinoids, anti-depressants, anti-epileptics, mood-stabilizers, anti-psychotics, or stimulants);\n4. history of chronic pain in shoulder or thumb (to avoid confounding at control stimulation points);\n5. recent (\\\u003C 3 months) illicit drug use;\n6. prior substance misuse\u002Fabuse;\n7. cold-activated diseases (including: agammaglobulinemia, cold urticaria, cold agglutinin disease, cryofibrinogenemia, cryoglobulinemia, immunosuppression, Raynaud's disease, collagen or autoimmune diseases, multiple myeloma, platelet deficiency disorders, pyoderma gangrenosum.)\n\n   \\- MRI-specific exclusions additionally include:\n8. Pregnancy or active attempts at conception;\n9. Implanted metal or electronic device;\n10. severe claustrophobia","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a clinical study of patients who have low back pain (for at least 6 months). The goal is to understand, with brain imaging, how auriculotherapy (an acupuncture-like stimulation of the ear) may work to relieve pain. There are 4 total study visits, divided into two pairs of visits that occur before and 5-7 days after receiving either a real or sham auriculotherapy treatment. The cryo-IQ device will be used, to stimulate 7 small areas on both ears with a focused jet of cold as a small amount of compressed gas is released. This is generally not painful, and less invasive, compared to using needles for auriculotherapy.",[27,28,29,30,31,32,33,34,35,36],"Low Back Pain","Chronic Low-back Pain","Back Pain, Low","Lumbar Disc Disease","Lumbar Discogenic Pain","Lumbar Pain Syndrome","Lumbar Post-Laminectomy Syndrome","Back Pain Lower Back Chronic","Back Pain Without Radiation","Pain;Back Low;Chronic",[38,39,40,41,42,43],"auriculotherapy","auricular stimulation","functional near-infrared spectroscopy","functional magnetic resonance imaging","functional connectivity","cryo-auriculotherapy","RECRUITING","2026-02-13",{"date":47,"type":48},"2026-02-18","ACTUAL",{"date":50,"type":48},"2025-07-30",{"date":52,"type":21},"2029-04-30",{"name":54,"class":55},"Keith M Vogt","OTHER"]