[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lung-adenocarcinoma-stage-i\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lung-adenocarcinoma-stage-i":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100503096","improving-the-intraoperative-diagnosis-accuracy-of-invasiveness-for-small-sized-lung-adenocarcinoma-100503096",false,"NCT05830812","Improving the Intraoperative Diagnosis Accuracy of Invasiveness for Small-sized Lung Adenocarcinoma","Improving the Intraoperative Diagnosis Accuracy for Pre-invasive and Invasive Small-sized Lung Adenocarcinoma Node by Combining Multi-modal Information","Inclusion Criteria:\n\nCT examination within 3 months before surgery Patients with operable clinical stage I lung cancer No previous treatment in the lungs or any other organ\n\n≥ 20 years and ≤ 80 years old Tumor less than 3cm in diameter on thin-slice (0.625-1 mm) CT images Lung adenocarcinoma confirmed by surgical resection and histopathological diagnosis\n\nExclusion Criteria:\n\nMarked artifacts on CT images History of preoperative treatment Incomplete clinical information or DICOM images History of other malignant tumors Lung cancer associated with cystic airspaces","ALL","20 Years","80 Years",{"count":20,"type":21},3000,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to improve the intraoperative diagnosis accuracy of invasiveness for small-sized lung adenocarcinoma by combining multi-modal information. The main question it aims to answer is whether multi-modal information have great value of prediction on the invasiveness for small-sized lung adenocarcinoma. Since a promising limited resection is largely based on intraoperative frozen section diagnosis, there is a growing demand on the high-accuracy of timely pathology diagnosis. The multi-modal information of participants will be collected retrospectively.",[25],"Lung Adenocarcinoma, Stage I",[27,28,29,30],"multi-modal information","lung adenocarcinoma","intraoperative diagnosis","invasiveness","RECRUITING","2024-09-12",{"date":34,"type":35},"2024-09-19","ACTUAL",{"date":37,"type":35},"2023-01-01",{"date":39,"type":21},"2026-12-31",{"name":41,"class":42},"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":43},"100312776","phase-2-surgery-with-or-without-chemotherapy-for-stage-i-nsclc-with-micropapillary-component--20-100312776","NCT03351842","Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component ≥ 20%","A PHASE II STUDY Of ADJUVANT CHEMOTHERAPY After SURGERY For STAGE I Lung ADENOCARCINOMA PATIENTS With MICROPAPILLARY COMPONENT More Than Or EQUAL To 20%","Inclusion Criteria:\n\n* Completely resected Stage I NSCLC as defined by the International Staging System\n* Pathologically diagnosed Stage I micropapillary predominant lung adenocarcinoma\n* Patients must be randomized within 4 weeks from the date of surgery\n* No prior chemotherapy or radiation for non-small cell lung cancer\n* Performance status of 0 or 1\n* Women must be non-pregnant and non-lactating; patients of childbearing potential must agree to use an effective form of contraception while on study\n* Patients must have no history of previous or concomitant malignancy, other than curatively treated carcinoma in situ of the cervix, or basal cell or squamous cell carcinoma of the skin, or surgically treated in situ carcinoma of the breast, or other cancer for which the patient has been disease free for five years\n* Granulocytes \\>= 1,800\u002Ful\n* Platelets \\>= 100,000\u002Ful\n* Bilirubin \\\u003C 1.5 mg\u002Fdl\n* SGOT(serum glutamic-oxaloacetic transaminase) (AST) \\\u003C 2.0 x ULN(upper limit of normal value)\n\nExclusion Criteria:\n\n* Do not meet the inclusion criteria\n* There is evidence of distant metastases\n* Suffered from other malignancies in five years\n* Within the past January subjects received other drug trials\n* Having serious allergies or idiosyncratic persons, such as you can not use folic acid, dexamethasone, vitamin B12 patients\n* Severe lung or heart disease, a history\n* Refuses or is unable to sign informed consent to participate in trials\n* The abuse of drugs or alcohol addicts.\n* Patients with difficult to control bacterial, viral, fungal infections\n* Having a personality or mental disorders, without civil capacity or restricted civil capacity.\n* Being pregnant or lactating women.","19 Years","70 Years",{"count":54,"type":21},460,"INTERVENTIONAL",[57],"PHASE2","Randomized phase II trial aims to compare surgery with or without adjuvant chemotherapy in treating patients who are pathologically diagnosed as stage I lung adenocarcinoma with micropapillary component no less than 20%.",[60,25,61,62],"Chemotherapy, Adjuvant","Treatment","Histological Type of Neoplasm",[64,65,66],"Adjuvant chemotherapy","Micropapillary Component","Early stage lung cancer","2017-12-17",{"date":69,"type":35},"2017-12-19",{"date":71,"type":35},"2017-09-01",{"date":73,"type":21},"2024-09-01",{"name":75,"class":42},"Shanghai Pulmonary Hospital, Shanghai, China"]