[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lung-lesions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lung-lesions":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100618697","impact-of-a-hypnotic-recording-on-artifacts-in-4d-ct-in-the-context-of-stereotactic-body-radiation-therapy-for-lung-cancer-100618697",false,"NCT07334990","Impact of a Hypnotic Recording on Artifacts in 4D CT in the Context of Stereotactic Body Radiation Therapy for Lung Cancer","HYPNOCT-4D","Inclusion Criteria:\n\n* Age ≥18 years,\n* Indication for lung SBRT, peripheral or central lesion,\n* Patient new to hypnosis (medical or stage hypnosis),\n* Patient covered by social security or equivalent,\n* Dated and signed consent form.\n\nExclusion Criteria:\n\n* Indication for treatment with abdominal compression,\n* Patient undergoing treatment for multiple lesions in the same treatment sequence,\n* Patient with an ultra-central lesion (distance to the mediastinum \\\u003C 2 cm),\n* Patient already included in this protocol,\n* Cognitive or physical disorders preventing the trial from proceeding smoothly,\n* Patient with one or more active psychotic disorders (such as schizophrenia),\n* Patients suffering from severe dissociative disorders,\n* Patient who does not understand French or is deaf,\n* Pregnant or breastfeeding women,\n* Patient under guardianship or curatorship or deprived of liberty.","ALL","18 Years",{"count":19,"type":20},25,"ESTIMATED","INTERVENTIONAL",[23],"NA","This is a single-center prospective cohort study evaluating the impact of a simple audio recording hypnosis system on the occurrence of artifacts on 4D CT scans in patients requiring SBRT radiotherapy for lung lesions (peripheral or central).\n\nThe primary objective of the study is to evaluate the use of a hypnotic recording on the reduction of artifacts in 4D CT scans for patients undergoing stereotactic body radiation therapy for lung cancer.\n\nThe secondary objectives are to evaluate:\n\n* the impact of hypnotic recording on the reduction of artifacts on intrathoracic structures (trachea, main bronchi, diaphragm, lesions, heart, and lungs),\n* the regularity of respiratory amplitude,\n* the regularity of respiratory rate,\n* the volume of Internal Target Volume (ITV),\n* the reproducibility of ITV volume,\n* patient satisfaction.\n\n  1. Before this dosimetric scan, the patient will complete a self-administered questionnaire on anxiety: the HADS-A questionnaire (Hospital Anxiety and Depression Scale-only questions relating to anxiety).\n\n     During this examination, the MERM explains the dosimetric scan procedure to the patient. After the immobilization system has been set up in accordance with the department's standard protocol, a 4D CT scan will be performed while asking the patient to breathe regularly. In the event of an artifact at the level of the lesion, a second 4D CT scan will be performed under the same conditions.\n  2. The hypnotic audio recording will be played through the room's speakers. The hypnotic recording is structured in three stages, with a 5-minute induction phase, a 5-minute working phase, and finally a 5-minute return phase.\n\n     After 5 minutes of playback, the 4D CT scan for the study is performed using the same acquisition parameters as the free 4D CT scan.\n  3. Following the first radiotherapy session and for all patients included in the study, a 4D dosimetric scan will be performed using the hypnotic recording again, as described above, in order to assess the inter-fraction reproducibility of the ITV volume.\n\nFollowing this second 4D CT scan under hypnosis, patient satisfaction will be assessed (using a Likert scale questionnaire).",[26,27],"Stereotactic Body Radiation Therapy","Lung Lesions",[29],"Hypnosis","NOT_YET_RECRUITING","2026-01-06",{"date":33,"type":34},"2026-01-12","ACTUAL",{"date":36,"type":20},"2025-12-30",{"date":38,"type":20},"2027-01-30",{"name":40,"class":41},"Centre Leon Berard","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":59,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100593428","robotic-assisted-bronchoscopy-under-moderate-sedation-with-propofol-100593428","NCT07006311","Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol","Robotic-assisted Bronchoscopy Under Moderate Sedation With Propofol: A Single-center Pilot Study.","Robofol","Inclusion Criteria:\n\n* informed consent signed by the subject\n* aged at least 18 years\n* scheduled for bronchoscopy with moderate sedation and tracheal intubation in order to obtain at least 1 specimens of the lung via transbronchial biopsy\n* necessary periinterventional laboratory examinations needed for the bronchoscopy\n* judgement of the subject\n\nExclusion Criteria:\n\n* endobronchial lesion causing lobar atelectasis\n* inability or contraindications to undergo bronchoscopy (e.g. severe cardiopulmonary diseases, coagulation disorders, intolerance to anesthesia or endoscopic operation, psychiatric disorders or severe neurosis)\n* pregnant or lactating women",{"count":51,"type":20},30,[23],"In this study, the investigators want to find out whether robot-assisted bronchoscopy also works with moderate sedation (Propofol), as is already used in standard bronchoscopies. The study is being conducted as a pilot study. This means that it is an initial test run for a scientific investigation. The investigators are testing on a small scale whether the intervention works as predicted before a larger study is conducted.",[27,55,56,57,58],"Robotic Assisted Bronchoscopy","Propofol","Bronchoscopy","Bronchoscopy Biopsy",[60,61,62,63],"Robotic-assisted bronchoscopy","robotic assisted bronchoscopy","diagnosis of lung lesions","moderate sedation","RECRUITING","2025-09-16",{"date":67,"type":34},"2025-09-22",{"date":69,"type":34},"2025-08-14",{"date":71,"type":20},"2026-06-01",{"name":73,"class":41},"University of Zurich",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":96,"leadSponsor":98,"locationsCount":74},"100597583","a-study-of-contrast-enhanced-ebus-in-lung-lesions-and-intrathoracic-lymph-nodes-100597583","NCT07060378","A Study of Contrast-enhanced EBUS in Lung Lesions and Intrathoracic Lymph Nodes","Inclusion Criteria:\n\n* Age \\>18 years old；\n* Enlargement of at least one intrathoracic LN (short diameter \\> 1 cm) or central parenchymal lung lesions adjacent to the airway detected on chest CT, or increased fluorodeoxyglucose uptake in at least one intrathoracic lymph node on PET \u002F CT (standardized uptake value \\> 2.5)；\n* CP-EBUS-TBNA is required to determine the diagnosis or staging, the patient agreed to undergo CE-EBUS, and there were no contraindications to EBUS-TBNA;\n* Patients who have good compliance and sign informed consent.\n\nExclusion Criteria:\n\n* Patients with known hypersensitivity to ultrasound contrast components;\n* Patients with severe pulmonary hypertension (pulmonary artery pressure \\> 90 mmHg);\n* Patients with angina pectoris, acute coronary syndrome, clinically unstable ischemic heart disease, heart failure, cardiac dysfunction, and cardiac disease with right-to-left shunting;\n* Patients with uncontrolled essential hypertension and adults with respiratory distress syndrome;\n* Pregnant or lactating women；\n* Patients with contraindications to bronchoscopy；\n* Patients with other conditions that, in the opinion of the investigator, make the patient unsuitable for the study.","90 Years",{"count":83,"type":20},250,[23],"Exploring the Clinical Application Value of Contrast Enhancement Features in CE-EBUS Images for the Diagnosis of Pulmonary Lesions and Intrapulmonary Lymph Nodes",[27,87],"Mediastinal and Hilar Lymph Node Enlargement",[89,90,91],"CE-EBUS","Ultrasound Contrast Agent","Microbubbles","2025-07-10",{"date":94,"type":34},"2025-07-11",{"date":92,"type":34},{"date":97,"type":20},"2026-01-30",{"name":99,"class":41},"Shanghai Chest Hospital"]