[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malignant-biliary-obstruction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malignant-biliary-obstruction":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,51,82,111,125,148,173,195],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100054303","12-mm-partial-covered-versus-bare-self-expandable-metallic-stents-for-malignant-distal-biliary-obstruction-100054303",false,"NCT07559968","12-mm Partial Covered Versus Bare Self-Expandable Metallic Stents for Malignant Distal Biliary Obstruction","12-mm Partial Covered Versus Bare Self-Expandable Metallic Stents for Malignant Distal Biliary Obstruction: A Prospective, Randomized Clinical Study","PCSEMS-12","Inclusion Criteria:\n\n* Patients who voluntarily provide written informed consent after receiving sufficient explanation of the study purpose, methods, and potential benefits and risks\n* Adults aged 19 years or older\n* Patients diagnosed with unresectable malignant distal biliary obstruction based on imaging studies (CT, MRI, ERCP, etc.) or histologic confirmation\n* Patients who have already undergone percutaneous transhepatic biliary drainage (PTBD) according to the institutional clinical protocol and are scheduled for metallic stent placement through the existing PTBD tract\n\nExclusion Criteria:\n\n* Patients with a previous history of biliary metallic stent placement\n* Patients with upper biliary obstruction (hilar level or above)\n* Patients with other major biliary lesions in addition to malignant distal biliary obstruction\n* Patients for whom the investigator judges that study conduct or data collection would be markedly difficult","ALL","19 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Metallic stents are commonly used for biliary drainage in patients with unresectable malignant distal biliary obstruction. However, it is unclear whether a 12-mm partially covered self-expandable metallic stent or a 12-mm bare self-expandable metallic stent provides better effectiveness and safety. This prospective, randomized clinical trial will compare these two stent types in adult patients who have already undergone percutaneous transhepatic biliary drainage (PTBD) and are scheduled for metallic stent placement through the existing PTBD tract. A total of 60 participants will be enrolled. After stent placement, participants will be followed for 12 months, with assessments at 3, 6, and 12 months. The study will evaluate recurrent biliary obstruction, stent patency duration, reintervention, overall survival, and procedure-related complications. The results are expected to provide evidence for selecting the most appropriate 12-mm metallic stent for patients with unresectable malignant distal biliary obstruction.",[27,28,29],"Malignant Distal Biliary Obstruction","Malignant Biliary Obstruction","Biliary Obstruction",[31,32,33,34,35,36,37],"12-mm metallic stent","partially covered self-expandable metallic stent","bare self-expandable metallic stent","malignant distal biliary obstruction","PTBD","recurrent biliary obstruction","stent patency","RECRUITING","2026-07-10",{"date":41,"type":42},"2026-07-13","ACTUAL",{"date":44,"type":42},"2026-05-27",{"date":46,"type":21},"2029-12-31",{"name":48,"class":49},"Chung-Ang University Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":62,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":50},"100635870","suprapapillary-metal-stent-vs-routine-transpapillary-drainage-in-malignant-hilar-biliary-obstruction-smart-b-trial-100635870","NCT07558304","Suprapapillary Metal Stent vs. Routine Transpapillary Drainage in Malignant Hilar Biliary Obstruction (SMART-B Trial)","Randomized Clinical Trial of Suprapapillary Drainage With Metal Stent vs. Routine Internal-External Transpapillary Drainage in Patients With Malignant Hilar Biliary Obstruction","SMART-B","Inclusion Criteria:\n\n1. Age \\>18 years.\n2. Malignant proximal biliary obstruction on imaging (magnetic resonance cholangiopancreatography or contrast-enhanced abdominal computed tomography) with histopathological confirmation or high clinical and radiological suspicion.\n3. Total bilirubin \\> 3 mg\u002FdL.\n4. Patients not candidates for potentially curative surgical resection due to locally advanced disease, metastatic disease, or inadequate clinical condition.\n5. Patients with potentially resectable neoplasms, defined as the possibility of achieving complete resection (R0), who meet at least one of the following criteria:\n\n5.1 Estimated future liver remnant \\\u003C40%, in whom percutaneous portal vein embolization of the side to be resected will also be indicated after initial drainage.\n\n5.2 Prolonged jaundice with total bilirubin \\>10 mg\u002FdL for more than 14 days. 5.3 Malnutrition, defined as ≥10% unintentional weight loss or albumin \\\u003C3 g\u002FdL, presumably attributable to cholestasis.\n\n5.4 Indication for neoadjuvant chemotherapy.\n\nExclusion Criteria:\n\n1. Tumor with distal extension to the duodenal papilla, precluding suprapapillary drainage.\n2. Prior biliary drainage procedure, either percutaneous (PTBD) or endoscopic (ERCP).\n3. Acute cholangitis, clinically defined as fever (axillary temperature \\>38°C) and leukocytosis (white blood cell count \\>10,000\u002Fmm³).\n4. Uncorrectable coagulopathy.\n5. Iodinated contrast allergy not amenable to desensitization.","18 Years",{"count":61,"type":21},84,[24],"Malignant hilar biliary obstruction is a condition in which the bile ducts near the liver become blocked due to cancer. This blockage can lead to jaundice (yellowing of the skin and eyes), itching, infection, and impaired liver function. To relieve the obstruction, doctors commonly perform procedures to drain bile and restore its flow.\n\nThere are different techniques available for biliary drainage. One common method is percutaneous transpapillary internal-external drainage, in which a catheter is placed through the liver and across the natural opening of the bile duct into the intestine. Another approach is percutaneous suprapapillary drainage using a self-expanding metal stent, which allows bile to drain without crossing into the intestine and may reduce the risk of contamination and infection.\n\nCurrently, there is no clear consensus on which of these two techniques is safer or more effective for patients with malignant proximal biliary obstruction. Some studies suggest that avoiding manipulation of the intestinal opening of the bile duct may reduce complications such as infection, but high-quality comparative evidence is lacking.\n\nThe purpose of this study is to compare percutaneous suprapapillary drainage with a self-expanding metal stent versus routine percutaneous transpapillary internal-external drainage in patients with malignant proximal biliary obstruction. The study aims to compare the rate of drainage-related complications between the two techniques, as well as to evaluate treatment success, stent patency, and the need for reintervention. In addition, in patients with potentially resectable disease undergoing preoperative biliary drainage, the study will assess and compare surgical outcomes between the two approaches. The results of this study may help determine the safest and most effective drainage strategy for these patients and improve future clinical decision-making.",[65,66,28],"Cholangiocarcinoma","Bile Duct Neoplasms",[65,68,69,70,71,28],"Percutaneous biliary drainage","Self-expanding metal stent","Suprapapillary drainage","Malignant hilar biliary obstruction","NOT_YET_RECRUITING","2026-06-12",{"date":75,"type":42},"2026-06-16",{"date":77,"type":21},"2026-06-15",{"date":79,"type":21},"2028-12-31",{"name":81,"class":49},"Hospital de Clinicas de Porto Alegre",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":92,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":109,"locationsCount":4},"100638664","comparison-of-a-short-modified-metal-stent-versus-plastic-stent-as-a-bridge-to-surgery-in-pancreatic-cancer-with-malignant-biliary-obstruction-100638664","NCT07606430","Comparison of a Short Modified Metal Stent Versus Plastic Stent as a Bridge to Surgery in Pancreatic Cancer With Malignant Biliary Obstruction","Multicenter Randomized Trial of a Short Modified 8-mm-diameter Fully Covered Metal Stent Versus Plastic Stent as a Bridge to Surgery in Pancreatic Cancer With Malignant Biliary Obstruction","BRIDGE-8","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Patients with resectable, borderline resectable, or locally advanced pancreatic cancer with distal malignant biliary obstruction requiring endoscopic biliary drainage\n3. Biliary stricture located ≥ 2 cm below the hepatic hilum\n4. Serum bilirubin ≥ 3 mg\u002FdL\n5. Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2\n6. Ability to provide written informed consent\n\nExclusion Criteria:\n\n1. Presence of distant metastasis\n2. Prior biliary stent placement for biliary obstruction\n3. Requirement for duodenal stent placement due to gastric outlet obstruction\n4. Estimated life expectancy \\\u003C 3 months\n5. Inability to undergo ERCP\n6. Any condition that, in the opinion of the investigator, would make participation unsafe or interfere with study outcomes",{"count":91,"type":21},116,[24],"This study is a multicenter, randomized clinical trial designed to compare the effectiveness and safety of a modified 8-mm fully covered self-expandable metal stent (FCSEMS) with a conventional plastic stent for preoperative biliary drainage in patients with pancreatic cancer and malignant biliary obstruction.\n\nIn patients who require biliary drainage before surgery, stent placement is commonly performed using endoscopic retrograde cholangiopancreatography (ERCP). However, the optimal stent type remains uncertain.\n\nParticipants will be randomly assigned to receive either the modified FCSEMS or a plastic stent. The primary objective is to evaluate the rate of stent-related complications requiring reintervention before surgery. Secondary outcomes include stent patency, adverse events, and surgical outcomes.\n\nThe results of this study are expected to help determine the most appropriate stent strategy for patients undergoing surgery for pancreatic cancer.",[95,28],"Pancreatic Cancer",[97,98,99,100,101,102],"pancreatic cancer","malignant biliary obstruction","preoperative biliary drainage","ERCP","fully covered self-expandable metal stent","plastic stent","2026-05-18",{"date":105,"type":42},"2026-05-26",{"date":107,"type":21},"2026-05-01",{"date":46,"type":21},{"name":110,"class":49},"Soonchunhyang University Hospital",{"id":112,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":25,"conditions":115,"keywords":116,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":123,"locationsCount":4},"100635998",{"count":20,"type":21},[24],[27,28,29],[31,32,33,34,35,36,37],"2026-04-30",{"date":119,"type":42},"2026-05-06",{"date":121,"type":21},"2026-05",{"date":46,"type":21},{"name":124,"class":49},"Chung-Ang University Hosptial, Chung-Ang University College of Medicine",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":133,"briefSummary":134,"conditions":135,"keywords":136,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":50},"100452276","eus-guided-hepatico-gastrostomy-using-a-novel-lumen-apposing-metal-stent-100452276","NCT05169398","EUS-guided Hepatico-gastrostomy Using a Novel Lumen Apposing Metal Stent","Inclusion Criteria:\n\n1. \\>= 18 years of age\n2. Anatomically feasible for EUS-guided hepatico-gastrostomy\n3. Patients with clinical symptoms and\u002For signs of extrahepatic biliary obstruction (jaundice, biliary-type pain, cholangitis)\n4. Patients with unsuccessful ERCP (failed ERCP, anticipated difficult ERCP or high risk for pancreatitis)\n5. Written informed consent (and assent when applicable) obtained from subject.\n\nExclusion Criteria:\n\n1. Pregnant, breastfeeding, or unwilling to practice birth control during participation in the study.\n2. Coagulopathic patients (INR\\>1.5, platelets \\\u003C50,000)",{"count":132,"type":21},20,[24],"EUS-guided biliary drainage is gaining popularity as a means of achieving endoscopic drainage in patients with failed endoscopic retrograde cholangiopancreatography (ERCP) 1. EUS-guided hepaticogastrostomy (HGS) is a type of EUS-guided biliary drainage and the procedure is employed when the ERCP fails due to a malignant bile duct obstruction but the papilla is inaccessible or if the first of the duodenum is infiltrated by tumor. Recently, a novel dedicated HGS (Niti-S, Taewoong Medical, Gyeonggi-do, Korea) has become available, the stent has a novel design to that prevents the stent from migration, further improving the safety.\n\nThe aim of the current study is to evaluate the feasibility and outcomes of the novel lumen apposing stent for EUS-guided HGS. The hypothesis is that the device is safe and effective.",[28],[28,137,138],"EUS-biliary drainage","EUS-guided hepaticogastrostomy","2026-03-19",{"date":141,"type":42},"2026-03-20",{"date":143,"type":42},"2022-01-15",{"date":145,"type":21},"2026-11-30",{"name":147,"class":49},"Chinese University of Hong Kong",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":50},"100601816","improving-a-bile-duct-drainage-procedure-in-patients-with-inoperable-cancer-blocking-the-bile-ducts-comparing-two-types-of-endoscopically-placed-internal-stents-to-prevent-blockage-of-a-lumen-apposing-metal-stent-100601816","NCT07115420","Improving a Bile Duct Drainage Procedure in Patients With Inoperable Cancer Blocking the Bile Ducts: Comparing Two Types of Endoscopically Placed Internal Stents to Prevent Blockage of a Lumen Apposing Metal Stent","Optimising EUS-guided Choledochoduodenostomy With Lumen Apposing Metal Stent With Stent in Stent Placement: a Randomised Study Between Double Pigtail Stent and Fully Covered Self-Expanding Metal Stent. The Opti-LAMS Study","Opti-LAMS","Inclusion Criteria:\n\n* Age ≥18 years.\n* Radiologically or histologically proven malignant distal bile duct obstruction with unresectable or metastatic disease, including those who have already failed ERCP\n* Indication for biliary drainage with presence of obstructive jaundice biochemically and dilated biliary system on imaging.\n* Informed consent provided.\n* Common bile duct (CBD) size of at least 12mm on EUS imaging\n\nExclusion Criteria:\n\n* Previous biliary stenting or surgery precluding EUS-CDS.\n* Inability to provide informed consent.\n* Pregnancy.\n* Significant coagulopathy that is not correctable.\n* Futility of intervention e.g. pre-terminal patients",{"count":157,"type":21},100,[24],"This study looks at the best way to treat bile duct blockage in people with advanced cancer that cannot be removed by surgery. A blocked bile duct can cause serious symptoms like yellowing of the skin (jaundice), infection, and pain.\n\nA common procedure called ERCP sometimes doesn't work in these patients. A newer method called EUS-guided choledochoduodenostomy (EUS-CDS) uses internal ultrasound to place a special metal tube (called a LAMS) to allow bile to drain. However, over time this stent can still become blocked.\n\nTo reduce this risk, doctors can place a second stent inside the first. This study is comparing two types of these second stents:\n\n* A plastic stent (double pigtail stent or DPS)\n* A metal stent (fully covered self-expanding metal stent or FCSEMS)\n\nThe study will include patients at Waikato Hospital. After the first stent is placed, they will be randomly assigned to receive either a DPS or FCSEMS. Patients will be followed for 6 months to see how well the stents work.\n\nThe aim is to find out which approach keeps the bile duct open longer and reduces the need for further procedures or hospitalisation, helping improve care and comfort for people with advanced cancer",[28,161,162,163],"Advanced Pancreatic Cancer and Cholangiocarcinoma","Inoperable Malignant Biliary Obstruction","Lumen Apposing Metal Stents","2025-08-03",{"date":166,"type":42},"2025-08-11",{"date":168,"type":21},"2025-09",{"date":170,"type":21},"2028-03",{"name":172,"class":49},"Waikato Hospital",{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":179,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":181,"targetDuration":4,"studyType":22,"phases":183,"briefSummary":184,"conditions":185,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":4},"100558427","proceeding-with-advanced-techniques-in-case-of-distal-malignant-biliary-obstruction-and-difficult-biliary-cannulation-compared-with-therapeutic-eus-the-prometheus-trial-100558427","NCT06550973","PROceeding With Advanced Techniques in Case of Distal Malignant Biliary Obstruction and Difficult Biliary Cannulation comparEd With Therapeutic-EUS: the PROMETHEUS Trial","Randomized, Multicentric Trial, PROceeding With Advanced Techniques in Case of Distal Malignant Biliary Obstruction and Difficult Biliary Cannulation comparEd With Therapeutic-EUS: the PROMETHEUS Trial","PROMETHEUS","Inclusion Criteria:\n\n* Age ≥18 years\n* Patients with distal malignant biliary obstruction\n* Abdominal ultrasound or computed tomography or magnetic resonance or EUS showing a dilated common bile duct \\> 15 mm diameter.\n* Difficult biliary cannulation defined as ESGE guidelines\n* Agree to receive follow up phone calls\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Coagulation and\u002For platelets hereditary disorders and\u002For INR\\>1.5, PLT\\\u003C50,000 103\u002Fmm3.\n* Use of anticoagulants that cannot be discontinued\n* Pregnant women\n* Previous ERCP or EUS-BD attempt\n* Inability to sign the informed consent",{"count":182,"type":21},220,[24],"Endoscopic retrograde cholangiopancreatography (ERCP) stands as the primary approach for addressing jaundice in individuals with distal malignant biliary obstruction. A premise element in achieving success during therapeutic ERCP is selective biliary cannulation (SBC). Nevertheless, SBC doesn't consistently yield favorable outcomes, even among expert endoscopists, failing in around 25% to 50% of cases with standard ERCP approach (sphincterotome and guidewire).\n\nIn such situations, depending on the endoscopist's experience and preference, various advanced techniques come into play. These encompass the double guidewire cannulation approach, needle-knife precut papillotomy or fistulotomy, and transpancreatic sphincterotomy, serving as potential rescue methods.\n\nIn recent times, the EUS-guided approach has been gaining increasing significance. Initially, it was viewed as a rescue option in cases where advanced ERCP techniques failed (5-15% of cases). More recently, it has proved its feasibility as a first line alternative to ERCP in scenarios involving malignant biliary obstruction.",[28],"2024-08-09",{"date":188,"type":42},"2024-08-13",{"date":190,"type":21},"2024-10-01",{"date":192,"type":21},"2026-09-30",{"name":194,"class":49},"Istituto Clinico Humanitas",{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":4,"enrollmentInfo":202,"targetDuration":4,"studyType":22,"phases":204,"briefSummary":205,"conditions":206,"keywords":208,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":50},"100544981","eus-guided-cds-vs-ercp-as-first-line-in-malignant-distal-obstruction-in-borderline-disease-carpediem-2-trial-100544981","NCT06375954","EUS-guided CDS vs ERCP as First Line in Malignant Distal Obstruction in Borderline Disease (CARPEDIEM-2 Trial)","Endoscopic Ultrasound-Guided Biliary Drainage With Lumen-Apposing Stent vs Classical ERCP for First-line Therapy of Malignant Distal Biliary Obstruction in Borderline Disease: An Open-label, Multicenter Randomized Trial (CARPEDIEM-2 Trial)","Inclusion Criteria:\n\n* Malignant distal biliary obstruction diagnosed in patient considered BORDERLINE with biliary drainage indication: i) impaired hepatic enzymes (including hyperbilirubinemia) x3 times upper the superior normal value. ii) Radiologic singns of extrahepatic bile duct obstruction with presence of retrograde dilatation, of at least 12-mm axial diameter.\n* Consensual malignancy by a bilio-pancreatic multidisciplinar committe (histological confirmation is not mandatory)\n* Patient capable of understanding and\u002For singning the informed consent.\n* Patient who understands the type of study and will comply with all follow-up tests throughout its duration\n\nExclusion Criteria:\n\n* Pregnancy or lactation.\n* Severe coagulation disorder: INR \\> 1.5 non correctable with plasma administration and\u002For platelet count \\\u003C 50.000\u002Fmm3.\n* Distal malignant biliary strictures in patients considered directly resectable, non-surgical, unresectable, or palliative\n* Benign or uncertain etiology of biliary strictures or strictures located proximally or in close proximity to the hilum.\n* Patients with prior biliary stents or other biliary drainages (e.g., PTCD).\n* Altered intestinal anatomy due to prior surgery that prevents or hinders papillary access (e.g., gastric bypass, Billroth II, duodenal switch, Roux-en-Y).\n* Stenosis in the antral or duodenal region that prevents access to the duodenum and reaching the papilla.\n* Situations that do not allow for upper gastrointestinal endoscopy (e.g., esophageal stricture).\n* Patients with functional diversity, who lack the capacity to understand the nature and potential consequences of the study, except when a legal representative is available.\n* Patients incapable of maintaining follow-up appointments (lack of adherence).\n* Lack of informed consent.",{"count":203,"type":21},96,[24],"The aim of this clinical trial is to evaluate temporal delay (days) between biliary drainage (EUS-CDS vs ERCP as first line therapy) and chemotherapy start in patients with borderline distal malignant biliary obstruction.",[28,95,207],"Biliary Tract Neoplasms",[209,210,211,212,100,213],"Choledochoduodenostomy","Therapeutic endoscopy","Biliary Drainage","Lumen apposing metal stent","Biliopancreatic malignancy","2024-04-18",{"date":216,"type":42},"2024-04-19",{"date":218,"type":21},"2024-05-01",{"date":220,"type":21},"2027-05-01",{"name":222,"class":49},"Hospital Universitari de Bellvitge"]