[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malignant-biliary-stricture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malignant-biliary-stricture":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100624273","phase-2-comparative-efficacy-of-intraductal-antibiotic-during-ercp-in-acute-cholangitis-100624273",false,"NCT07407491","Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis","Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* The patients diagnosed with mild and moderate acute cholangitis based on TG 18\n* Planned for ERCP within 48 hours\n* 18 years old and above\n\nExclusion Criteria:\n\n* Severe acute cholangitis\n* History of antibiotic hypersensitivity\n* Receiving cancer chemotherapy, steroids, or immunosuppressive agents\n* Concomitant infections\n* Recent biliary interventions such as percutaneous transhepatic biliary drainage (PTBD) within last 3 months\n* Known or suspected perforated tympanic membrane, myasthenia gravis","ALL","18 Years",{"count":19,"type":20},172,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis compared with standard systemic antibiotic therapy alone?",[26,27,28,29,30],"Acute Cholangitis","Biliary Tract Infection","Biliary Obstruction","Choledocholithiasis","Malignant Biliary Stricture",[26,32,33,34,29],"ERCP","Intraductal antibiotics","Biliary tract infection","RECRUITING","2026-02-05",{"date":38,"type":39},"2026-02-12","ACTUAL",{"date":41,"type":39},"2024-07-09",{"date":43,"type":20},"2026-07-08",{"name":45,"class":46},"National University of Malaysia","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":47},"100590208","raman-spectroscopy-in-the-diagnosis-of-extrahepatic-cholangiocarcinoma---a-pilot-study-100590208","NCT06964425","Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study","Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma","Inclusion Criteria:\n\n* person older than 18 years, who has known extrahepatic cholangiocarcinoma and is indicated for ERCP\n\nExclusion Criteria:\n\n* disagreement with the study",{"count":56,"type":20},20,[58],"NA","Diagnosis of extrahepatic cholangiocarcinoma is challenging because the yield of imaging and tissue sampling is limited. Raman spectroscopy is an optical method based on the analysis of scattered monochromatic light. Raman spectroscopy is able to provide a molecular 'fingerprint' of the tissue to determine its type. The aim of this pilot study was to develop a methodology for in vivo Raman spectroscopy in bile ducts to improve the current diagnostic capabilities of extrahepatic cholangiocarcinoma.",[61,62,63,64,65,66,67,68,30],"Cholangiocarcinoma, Extrahepatic","Cholangiocarcinoma of the Extrahepatic Bile Duct","Cholangiocarcinoma, Perihilar","Diagnosis","Raman Spectroscopy","Klatskin Tumor","Endoscopy","Biliary Stricture","2025-06-29",{"date":71,"type":39},"2025-07-02",{"date":73,"type":39},"2023-02-04",{"date":75,"type":20},"2025-07-30",{"name":77,"class":46},"University Hospital Olomouc"]