[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malignant-gastric-outlet-obstruction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malignant-gastric-outlet-obstruction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100525921","comparing-endoscopic-ultrasound-vs-surgical-gastrojejunostomy-for-management-of-goo-100525921",false,"NCT06128018","Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.","A Randomized Trial Comparing Endoscopic UltraSound-guided GasTrojejunostomy (EUS-GJ) and Surgical GastrojejunOstomy (S-GJ) for the Management of Malignant gastRic outlEt Obstruction","RESTORE","Inclusion Criteria:\n\n1. ≥ 18 years of age.\n2. Radiographic OR Endoscopic evidence of an obstructing neoplasm in the distal stomach or duodenum.\n3. GOOSS of 0 or 1\n4. BOTH surgical and endoscopic GJ are technically and clinically feasible\n5. Can understand and is willing to sign informed consent form prior to the initiation of any study procedures (or when applicable the subject's LAR).\n\nExclusion Criteria:\n\n1. \\\u003C 18 years of age\n2. ECOG \\>2\n3. Expected survival (determined by the treating oncologist) is less than 2 months.\n4. Candidates for potential resection of the cancer and obstructed anatomical area (this includes patients with borderline resectable pancreatic cancer)\n5. Peritoneal carcinomatosis with associated bowel obstruction on imaging or during laparoscopy\n6. Large volume ascites (patients with moderate volume ascites may undergo IR guided drainage prior to randomization)\n7. Anatomical factors that technically hinder EUS-GJ OR Surgical-GJ (diffuse tumor involvement in path of LAMS or surgery, surgically altered anatomy that interferes with the ability to perform an anastomosis etc)\n8. Pregnancy","ALL","18 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this interventional study is to learn about the outcomes between two options for the management of malignant gastric outlet obstruction.",[27],"Malignant Gastric Outlet Obstruction","RECRUITING","2026-04-23",{"date":31,"type":32},"2026-04-27","ACTUAL",{"date":34,"type":32},"2023-11-01",{"date":36,"type":21},"2027-03-08",{"name":38,"class":39},"AdventHealth","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":22,"phases":49,"briefSummary":50,"conditions":51,"keywords":56,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":40},"100600392","eus-directed-transenteric-ercp-edee-in-patients-with-benign-and-malignant-underlying-conditions-and-inaccessible-papillabiliodigestive-anastomosis-bda-100600392","NCT07096895","EUS-directed Transenteric ERCP (EDEE) in Patients With Benign and Malignant Underlying Conditions and Inaccessible Papilla\u002FBiliodigestive Anastomosis (BDA)","Inclusion Criteria:\n\n* signed consent form\n* Indication for an EDEE\n* Age \\>18 years\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years",{"count":48,"type":21},40,[24],"Safety and efficacy of EDEE (EUS-directed transenteric ERCP)",[52,53,27,54,55],"Biliary Intervention","Altered Anatomy","EUS Guided Enteroenteric Anastomosis","EDEE",[57,58,59,60],"ERCP","altered anatomy","EUS","anastomosis","2025-07-24",{"date":63,"type":32},"2025-07-31",{"date":65,"type":32},"2020-02-01",{"date":67,"type":21},"2027-01-01",{"name":69,"class":39},"Evangelisches Krankenhaus Düsseldorf",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":81,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":40},"100515083","roux-en-y-gastric-bypass-versus-loop-gastrojejunostomy-for-malignant-gastric-outlet-obstruction-100515083","NCT05986890","Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction","Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form.\n2. Stated willingness to comply with all study procedures and availability for the duration of the study.\n3. Male or female aged ≥18 years old.\n4. Patients with a diagnosis of malignant gastric outlet obstruction. i. Defined as malignant cancer growth of any organ origin in the area of the distal stomach or duodenum preventing normal gastric emptying as determined by symptoms and cross-sectional imaging studies.\n\n   ii. Symptoms can include abdominal distention, abdominal pain, nausea and vomiting.\n\n   iii. Cross sectional imaging findings can include tumor growth in the area of the distal stomach or duodenum, gastric distention, fluid filled stomach and decompressed bowel distal to obstruction point.\n5. Patients deemed to benefit from surgical bypass as opposed to stent placement, by the primary surgeon. This includes assessing participants survival chances and ability to undergo a surgical procedure.\n6. Patients in a general health status that permits abdominal surgery under general anesthesia. As determined by primary surgeon and anesthesiologist.\n\nExclusion Criteria:\n\n1. Patients that have had previous treatment for malignant gastric outlet obstruction.\n\n   a. Including any previous surgery or stent placement for MGOO\n2. Patients with MGOO deemed to benefit more from endoscopic stent placement rather than surgery for symptom relief. This assessment will be at treating surgeon's discretion.",{"count":77,"type":21},16,[24],"This study is intended to investigate whether roux-en-y bypass surgery is superior to conventional loop gastrojejunostomy for Malignant gastric outlet obstruction in terms of tolerance to solid food intake. We hypothesize that roux-en-y bypass will be associated with improved solid food intake in the first 30 days after surgery.",[27],[82,83,84,85,86,87],"MGOO","Malignant gastric outlet obstruction","gastric outlet","malignant tumor","proximal bowel obstruction","bowel obstruction","2025-06-13",{"date":90,"type":32},"2025-06-17",{"date":92,"type":32},"2023-08-17",{"date":94,"type":21},"2026-12-01",{"name":96,"class":39},"Corewell Health West"]