[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malnourishment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malnourishment":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100509320","the-effect-of-high-caloric-oral-nutritional-supplements-on-growth-and-development-of-malnourished-children-100509320",false,"NCT05911893","the Effect of High Caloric Oral Nutritional Supplements on Growth and Development of Malnourished Children","EHCONSGDMC","Inclusion Criteria:\n\n* Aged 1-3 years\n* BMI for Age Z-score\\\u003C-2\n* Height-for-age z score\\\u003C-2\n* Total daily energy intake\\\u003C75% of recommended nutrient intake\n* The child's guardian is willing to participate in this study and sign an informed consent form.\n\nExclusion Criteria:\n\n* Chronic or severe infectious disease (e.g., chronic hepatitis, HIV or tuberculosis infection)\n* Certain congenital or genetic diseases affecting physical growth and development (congenital heart disease, Down's syndrome, infantile anorexia nervosa, etc.), malignancies and use of drugs (diuretics, appetite stimulants, steroids and growth hormones, etc.)\n* Severe gastrointestinal disorders (e.g., celiac disease, short bowel syndrome, inflammatory bowel disease, etc.)\n* Acute and chronic respiratory\u002Fdigestive tract infections within 2 weeks prior to enrollment\n* Allergy or contraindication to any of the ingredients in the high-energy total nutrition formula used in this study\n* Have used high-energy enteral nutrition preparations for the last 3 months","ALL","1 Year","3 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to investigate the effect of high caloric oral nutritional supplements on body proportion, weight, linear growth pattern, neuropsychological development level and related health aspects (gut health, immune function, quality of life, etc.) in participants aged 1 to 3 years who are malnourished (underweight and wasting),as well as to evaluate the safety of applying high caloric oral nutritional supplements. Participants will receive nutritional education and daily high caloric oral nutritional supplements(experimental group),or will receive nutritional education and dietary instruction(control group).This study may provide data to support the development of clinical intervention strategies for malnourished Chinese children.",[27,28,29,30],"Malnutrition, Child","Malnourishment","Nutritional Deficiency","Undernutrition",[32,33,34],"Oral Nutritional Supplements","Physique Growth","Neuropsychological Development","RECRUITING","2026-03-16",{"date":38,"type":39},"2026-03-18","ACTUAL",{"date":41,"type":39},"2024-06-17",{"date":43,"type":21},"2026-03-10",{"name":45,"class":46},"Children's Hospital of Chongqing Medical University","OTHER",13,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":83},"100612375","nutritional-management-of-the-patient-with-type-2-diabetes-at-nutritional-risk-or-with-malnutrition-in-clinical-practice-100612375","NCT07252765","Nutritional Management of the Patient With Type 2 Diabetes at Nutritional Risk or With Malnutrition in Clinical Practice","Nutritional Management of the Patient With Type 2 Diabetes at Nutritional Risk or With Malnutrition in Clinical Practice. STARLIGHT Study","STARLIGHT","Inclusion Criteria:\n\n* Adult patients diagnosed with type 2 diabetes (T2D) or drug-induced diabetes\n* Patients at nutritional risk according to MUST or presenting malnutrition according to GLIM criteria.\n* Patients requiring a diabetes-specific oral nutritional supplement (ONS) that is high-calorie, high-protein, and contains soluble fiber in real-world clinical practice, and who have been prescribed such a supplement within the previous 7 days.\n* Patients able to provide informed consent and complete the study questionnaires.\n\nExclusion Criteria:\n\n* Patients participating in other studies or clinical trials related to malnutrition, or who, in the investigator's opinion, may alter the course of the study.\n* Patients currently receiving or expected to receive other types of nutritional interventions involving supplements (oral or otherwise) or non-conventional feeding methods (e.g., feeding tubes).\n* Patients with a history of metabolic\u002Fendocrine diseases (other than diabetes) or any other condition causing liver or kidney failure, defined as ALT \\> 3x ULN or eGFR \\\u003C 30 ml\u002Fmin\u002F1.73 m², and according to the investigator's judgment.\n* Patients expected to undergo any surgical intervention or require hospitalization due to a condition unrelated to the study during the study period.\n* Patients with other conditions that, in the investigator's opinion, may interfere with adherence to the intervention or with study procedures.","18 Years",{"count":58,"type":21},334,"OBSERVATIONAL","The objective of this observational study is to characterize the patient profile and nutritional treatment patterns of individuals with type 2 diabetes (T2D) or drug-induced diabetes who present with malnutrition, or are at risk of it, and who are prescribed a diabetes-specific oral nutritional supplement (ONS) that is high in calories and protein and contains soluble fiber.\n\nParticipants will complete a series of questionnaires during visits 1 and 3.",[62,63,28,64],"Type 2 Diabetes Mellitus (T2DM)","Malnutrition","Drug-Induced Diabetes",[66,67,68,69,70,71,28,63,72],"Metabolic control","Disease - realted malnutrition","Diabetes-specific formula","T2D","Oral nutritional supplementation","Type 2 Diabetes Mellitus","Drug-induced diabetes","2026-01-26",{"date":75,"type":39},"2026-01-28",{"date":77,"type":39},"2025-11-20",{"date":79,"type":21},"2026-10",{"name":81,"class":82},"Outcomes'10","NETWORK",12,{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":4,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":105,"locationsCount":107},"100468433","phase-2-nutritional-supplementation-in-head-and-neck-cancers-100468433","NCT05379712","Nutritional Supplementation in Head and Neck Cancers","A Randomized Open Label Trial of Multimodal Oral Nutritional Supplementation Versus Standard Care, to Prevent \u002F Attenuate Malnutrition in Patients with Cancers of the Head and Neck Receiving (chemo)-radiotherapy Treatment.","Inclusion Criteria:\n\n1. Patients must have the ability to read, understand, and sign an informed consent and must be willing to comply with study treatment and follow-up.\n2. Male or female\n3. ≥18 years of age\n4. Histopathologically confirmed primary squamous cell carcinoma of the oral cavity and oropharynx, larynx or hypopharynx, who have agreed to receive radical intent radiotherapy as primary treatment or adjuvant treatment post-surgery, with or without platinum chemotherapy\n5. Capable of volitional oral nutritional intake at baseline.\n6. A diagnostic CT image taken with a maximum of 30 days before initiation of radical intent radiotherapy. If the CT scan history in the patient's clinical record does not include a study within this window, a baseline non-contrast enhanced CT abdomen will be conducted.\n7. An Eastern Cooperative Oncology Group Performance Status of ≤ 2\n\nExclusion Criteria:\n\n1. Fed by nasogastric tube, gastrostomy or total parenteral nutrition\n2. Cancer of the nasopharynx, thyroid or salivary gland\n3. Life expectancy \\\u003C6 months.\n4. A known hypersensitivity \u002F allergy to the investigational product or to any ingredient in their formulations (e.g. Milk\u002FLactose, Fish).\n5. Enrolment in any other clinical protocol or investigational study with an interventional agent or assessments that may interfere with study procedures.\n6. Patients with untreated brain metastases (patients with previously resected and\u002For radiated brain metastases without neurologic symptoms are permitted).\n7. Poorly controlled chronic illnesses or other inflammatory diseases (e.g. COPD, uncontrolled non-insulin dependent diabetes, rheumatoid arthritis).\n8. In the investigators' opinion, patients who have medical conditions that could interfere with nutrient metabolism or absorption (e.g., short bowel syndrome, Crohn's disease, etc.)",{"count":92,"type":21},81,[94],"PHASE2","The purpose of this study is to determine whether multimodal nutrition therapy (primary nutrition intervention + adjuvant nutrition therapy) will support patients to optimize their total caloric intake during cancer treatment by measuring the difference in mean cumulative energy intake between the intervention and control group over the duration of cancer treatment.",[28,29,30],[98,32],"Nutritional Support","2025-03-25",{"date":101,"type":39},"2025-03-28",{"date":103,"type":39},"2024-10-25",{"date":79,"type":21},{"name":106,"class":46},"AHS Cancer Control Alberta",1]