[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malnutrition-calorie\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malnutrition-calorie":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,50,75,99,149,178,199,252,278,305,342],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100639806","nutritional-status-in-adults-with-diabetic-foot-ulcers-100639806",false,"NCT07621770","Nutritional Status in Adults With Diabetic Foot Ulcers","Nutritional Status in Adults With Diabetic Foot in an Outpatient Wound Clinic: A Feasibility and Pilot Study","NutriDFU-P","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Diagnosed with diabetes type 1 or type 2\n* Presence of one or more DFUs\n* Receiving treatment in a participating outpatient wound clinic\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Above ankle amputation of the contralateral leg\n* Current treatment with intravenous antibiotics for acute infection.\n* Current hospitalisation for acute surgical management of the foot ulcer\n* Declining or unable to participate in a telephone follow-up interview.\n* Current long-term enteral (tube feeding) or parenteral nutritional support.\n\nExclusion criteria for bioelectrical impedance analysis (BIA)\n\n\\- Presence of a cardiac pacemaker or other implanted electronic device","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","OBSERVATIONAL","This feasibility and pilot study has two aims. The primary aim is to assess the feasibility of collecting clinical, nutritional, and functional data among adults with diabetic foot ulcers (DFUs) who are treated at an outpatient wound clinic. Specifically, the study will evaluate recruitment and inclusion rates, the relevance and clinical utility of selected variables, and assess the completeness and reliability of data collection.\n\nThe secondary aim is to provide a preliminary characterisation of nutritional status, dietary intake, body composition, muscle strength, mobility, and wound-related quality of life, to inform the design and methodology of a future full-scale national study.\n\nDFUs are associated with delayed healing, recurrent infections, reduced quality of life, and increased risk of hospitalization and amputation. These conditions are frequently accompanied by systemic inflammation, impaired circulation, and metabolic disturbances, which may increase nutritional requirements and negatively affect wound healing.\n\nDespite nutrition being recognized as a modifiable factor of ulcer healing, the nutritional status of individuals with DFUs remains insufficiently characterised, and evidence regarding clinically relevant nutritional deficiencies in this population is limited.\n\nParticipants will undergo assessment of height, weight, body composition, handgrip strength, and a 24-hour dietary recall interview during an outpatient clinic visit. Nutritional screening questionnaires and patient-reported measures of appetite, nutritional impact symptoms, mobility, and quality of life will be collected through telephone interviews within one week of the clinical visit.\n\nEligible participants are adults (\\>18 years) who are referred to the outpatient wound clinic with a hard-to-heal foot ulcer. Participants must be able to communicate in Danish or English.",[25,26,27,28,29,30,31],"Diabetic Foot Ulcers (DFU)","Nutrition Assessment","Malnutrition (Calorie)","Ulcer Foot","Dietary Intake Assessment","Bio-Impedance Measurements","Wound Healing",[33,34,35,36,37,38],"DFU","Malnutrition","Wound healing","Nutritional assessment","outpatient","hard-to-heal ulcer","NOT_YET_RECRUITING","2026-05-29",{"date":42,"type":43},"2026-06-02","ACTUAL",{"date":42,"type":21},{"date":46,"type":21},"2026-10-30",{"name":48,"class":49},"Hvidovre University Hospital","OTHER",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100612552","optimizing-patient-treatment-with-epa-enriched-nutrition-a-randomised-control-trial-100612552","NCT07255066","Optimizing Patient Treatment With EPA-enriched Nutrition, a Randomised Control Trial","OPT-EPA","Inclusion Criteria:\n\n* Participants with stage III-IV lung and\u002For colorectal cancer undergoing systemic anti-cancer treatment (SACT) or starting SACT within the next 4 weeks \\*with non-curative intent\n* Participants aged 18 or older\n* Participants at nutritional risk defined as a BMI \\\u003C20 kg\u002Fm2 and\u002For weight loss between 5-10% in the previous 6 months\\*\\*\n* Participants with systemic inflammation within 28 days of screening (e.g. CRP \\>10 mg\u002FdL)\n* Participants with an ECOG-PS\\*\\*\\* score of 0, 1 or 2\n* Participants willing and able to give written informed consent\n\nExclusion Criteria:\n\n* Participants with a recent history of tumour resection (within 12 months)\n* Participants who have lost \\>10% body weight in the previous 6 months before baseline - observed or participant reported.\n* Participants with severe renal or hepatic failure or an intolerance to any of the ingredients of the study product\n* Participants who are using dietary counselling, ONS or any form of artificial feeding at the time of recruitment\n* Unable to adhere to either arm of the trial and appropriate requirements\n* Contraindication to ONS including a lactose intolerance\n* Females who are pregnant or of childbearing potential and not using adequate contraception",{"count":58,"type":21},118,"INTERVENTIONAL",[61],"NA","Malnutrition is a common and serious issue for people living with cancer. Many cancer patients experience weight loss, muscle weakness, and poor quality of life due to malnutrition. This can also reduce the success of cancer treatments, increase hospital visits, and add emotional distress for both patients and their loved ones.\n\nTreating malnutrition through good nutritional care is increasingly recognised as an important part of cancer treatment. Leading experts recommend that all cancer patients be checked for signs of malnutrition and given personalised nutrition plans when necessary. While dietary counselling and oral nutritional supplements (ONS) are often used to help patients, there is still a need for better evidence to show how well these interventions work.\n\nA key factor contributing to malnutrition in cancer patients is inflammation. Omega-3 fatty acids, (like those found in oily fish) are known for their anti-inflammatory properties. Some studies suggest that omega-3s may help cancer patients by reducing inflammation, keeping muscles strong, improving appetite, and enhancing overall well-being.\n\nThe OPT-EPA study will investigate whether a nutritional drink, called Fortimel Forticare Sensations (FFS), can improve nutritional status in patients with lung or colorectal cancer who are at risk of malnutrition. This drink is enriched with omega-3 fatty acids (Eicosapentanoic acid (EPA) and Docosahexaenoic acid (DHA)) and provides a high amount of protein and calories in a small volume, making it easier to consume, especially for patients with taste changes.\n\nIn this study, participants will be divided into two groups. The experimental group will receive dietary counselling and standard care along with FFS, the omega-3-enriched nutritional drink, while the other (control) group will receive dietary counselling and standard care, with supplements provided only if clinically necessary. Researchers will evaluate the impact on patients' nutritional status, body weight, muscle, inflammation levels, and quality of life.\n\nThrough the OPT-EPA study, researchers hope to gain clearer insights into whether omega-3-containing supplements can provide meaningful benefits for cancer patients. Ultimately, this could help improve the quality of care and outcomes for people facing cancer-related malnutrition.",[27,64,65],"Colorectal Cancer","Lung Cancer","2026-05-01",{"date":68,"type":43},"2026-05-04",{"date":70,"type":21},"2026-06",{"date":72,"type":21},"2027-06",{"name":74,"class":49},"University of Edinburgh",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":93,"leadSponsor":95,"locationsCount":98},"100633301","stunting-and-targeting-reduction-of-impaired-growth-in-kids-effectively-100633301","NCT07524907","Stunting and Targeting Reduction of Impaired Growth in Kids Effectively","STRIKE: Stunting and Targeting Reduction of Impaired Growth in Kids Effectively: A Community Engaged Comprehensive, Multi-Faceted Nutrition Quality Improvement Program","STRIKE","Household Component\n\nInclusion\n\n* Children aged 1-5 years experiencing stunting or its risk (defined as HAZ ≤ -1 SD at baseline)\n* Children's legal guardian agrees to participate in the study\n* Full term pregnancy (defined as ≥ 37 weeks gestation and ≥ 2500g birth weight)\n* Residence in study area attending Children International (NGO) centers\n\nExclusion\n\n• Children who have current medical conditions requiring hospitalization: gastrointestinal tract infections or inflammatory bowel disease; active tuberculosis; acute hepatitis B or C; human immunodeficiency virus OR malignancy; cystic fibrosis; immunodeficiency syndromes, congenital abnormalities of the respiratory tract, such as lung and respiratory cilia; an unsuspected foreign body in the respiratory tract; asthma; heart abnormalities; abdominal hernias; and known metabolic disorders, renal impairment, or rheumatic diseases and diabetes\n\n* Congenital condition\n* Children with disabilities such as cerebral palsy, autism spectrum disorder, neurodegenerative disorders\n* Children with chronic or acute infections e.g. HIV, malaria\n* Children who are taking medications or other agents that could potentially affect body weight, including diuretics, appetite stimulants, steroids, and growth hormones\n* Children who have genetic conditions impacting weight status such as but not limited to: Bardet-Biedl Syndrome, Prader-Willi Syndrome\n* Children already enrolled in a nutrition program that includes a supplement\n* Participant has an allergy or intolerance to any ingredient in the study supplement, as reported by the parent.\n* Children with sleep disorders such as but not limited to: obstructive sleep apnea, insomnia, parasomnias (sleepwalking, night terrors, bedwetting), delayed sleep phase syndrome, behavioral sleep disorders, circadian rhythm disorders\n* Mental health disorders such as but not limited to: anxiety, depression\n\nOrganization Component\n\nInclusion\n\n* NGO staff taking part in nutrition screenings\n* Agrees to participate in survey\n\nExclusion\n\n* Not involved in the implementation of the study\n* Not involved in working with pediatric stunting or its risk\n* Declines participation in survey","1 Year","5 Years",{"count":86,"type":21},150,"The objective of this prospective, real-world evidence\u002Fpragmatic study with a quality improvement program approach is to evaluate the feasibility and effectiveness of a community-engaged nutrition-focused program utilizing nutrition screening, education, supplementation and continuous follow up for children and their families.",[27],"2026-04-06",{"date":91,"type":43},"2026-04-13",{"date":70,"type":21},{"date":94,"type":21},"2028-01",{"name":96,"class":97},"Abbott Nutrition","INDUSTRY",1,{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":17,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":59,"phases":111,"briefSummary":112,"conditions":113,"keywords":118,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":98},"100610251","goat-milk-derived-formula-vs-undiluted-goat-milk-in-infants-unable-to-exclusively-breastfeed-growth-and-biomarker-analysis-100610251","NCT07225153","Goat Milk-Derived Formula vs. Undiluted Goat Milk in Infants Unable to Exclusively Breastfeed: Growth and Biomarker Analysis","Goat Milk-Derived Formula Alternatives vs. Undiluted Goat Milk in Babies Unable to Exclusively Breastfeed: Analysis of Growth Metrics and Biological Markers","GMDFA","Inclusion Criteria:\n\n* • Infants aged = 08 -10 weeks with WAZ better than -1.8. (NIPS \\& ICF, 2019) Age Sex WAZ Weight in Kilograms 2 Month Boys WAZ\\>-1.8 4-5 kg 2 Month Girls WAZ\\>-1.8 4-5 kg Table 3: WAZ scores\n\n  * Living in Matiari District.\n  * Who has access to goat milk in their households.\n  * The Breastfeeding group: Women who exclusively breastfeeding and not giving and sort of formula or animal derived milk.\n  * Intervention Group: Women who do not breastfeed at all or give goat milk to their infants (2-3 feeds per day).\n  * No birth deformities\n\nExclusion Criteria:\n\n* • Infant birth weight \\\u003C WAZ -1.8 i.e. weight-for-age based on established growth standards, such as the World Health Organization (WHO).\n\n  * Birth deformities or disorders, such as genetic disorders, aerodigestive problems, or congenital anomalies.\n  * Plan to migrate during the next six months.\n  * We will exclude the women who exclusive breast feed and continue breast feeding for first 4 months.\n  * If the child is enrolled or included in any other interventional trial.\n  * Who does not have access to goat milk in their households.\n  * Are medically disqualified: Any potential participant who is deemed medically unfit for enrollment, due to the presence of severe or unstable health conditions that could compromise safety or interfere with the study outcomes, will be excluded from participation","8 Weeks","10 Weeks",{"count":110,"type":21},15,[61],"The goal of this clinical trial is to learn if Goat Milk-Derived Formula Alternatives (GMDFA) are safe and effective for infants who are unable to be exclusively breastfed. It will also study growth patterns, biological markers, and gut microbiome differences among infants receiving GMDFA, undiluted goat milk, or breast milk.\n\nThe main questions it aims to answer are:\n\n1. Do infants receiving GMDFA show similar growth patterns to those who are breastfed?\n2. Are biological markers of gut health and nutrition (such as calprotectin, lipocalin-2, CRP, and claudin) comparable between the groups?\n3. How do feeding types (GMDFA, goat milk, or breast milk) influence the infant gut microbiome composition, metabolic pathways, and lipid profiles?\n4. Is GMDFA a safe and nutritionally adequate feeding option for infants unable to be exclusively breastfed?\n\nWe will compare GMDFA, undiluted goat milk, and breast milk (reference group) to evaluate infant growth, gut health, and metabolic outcomes.\n\nParticipants will:\n\nBe randomly assigned to one of three feeding groups: GMDFA, undiluted goat milk, or breastfed\n\nAttend regular follow-up visits for growth measurements and sample collection (blood, stool, and breast milk where applicable)\n\nHave feeding practices monitored and recorded through caregiver interviews and feeding logs\n\nAdditional Analyses:\n\nMicrobiome analysis: to identify gut bacterial diversity and composition across feeding groups Metagenomic analysis: to explore functional genes and metabolic pathways related to nutrition and gut health Lipidomic analysis: to assess differences in lipid and fatty acid profiles in breast milk, goat milk, and infant samples",[27,114,115,116,117],"Infant Nutrition Disorder","Growth Flatering","Gut Microbiome","Lipidomics",[119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,117,137,138],"Infant nutrition","goat milk","Infant feeding practices","Breastfeeding","Breastfeeding Alternatives","Alternate feeding practices","Growth outcomes","Infant growth metrics","Gut microbiome","Gut inflammation biomarkers","Calprotectin","Lipocalin-2","Claudin-2","C-reactive protein (CRP)","Randomized controlled trial","Rural Pakistan","Infant health","Malnutrition prevention","Breast milk","Metagenomics","RECRUITING","2026-03-25",{"date":142,"type":43},"2026-03-30",{"date":144,"type":43},"2025-08-30",{"date":146,"type":21},"2026-03-18",{"name":148,"class":49},"Aga Khan University",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":17,"minAge":84,"maxAge":18,"enrollmentInfo":156,"targetDuration":4,"studyType":59,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":98},"100624680","rems25-study-on-the-use-of-rems-technology-in-diseases-commonly-associated-with-reduced-bone-mineral-density-bmd-100624680","NCT07412782","REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)","Observational Study for the Assessment of Bone Mineral Density (BMD) Using REMS Technology","Inclusion Criteria:\n\n* Written informed consent from adult patients or parents\u002Flegal guardians\n* Age between 5 and 18 years\n* Both sexes and all ethnicities\n* Known condition negatively affecting bone health\n\nExclusion Criteria:\n\n\\- Age below 5 years or over 18 years",{"count":157,"type":21},100,[61],"This study evaluates bone mineral density (BMD) in pediatric patients aged 5-18 years with conditions negatively affecting bone health, using REMS (Radiofrequency Echographic Multi Spectrometry), a non-invasive and radiation-free ultrasound technology. Bone health is crucial during childhood, when peak bone mass develops, and reduced BMD is associated with increased fracture risk. DXA is the current reference method but has limitations in children, including radiation exposure and growth-related measurement issues. REMS has been validated in adults and shows promise in pediatrics, despite the lack of reference values. The study is a single-center, national, non-profit interventional study lasting about 12 months. Participants will undergo REMS BMD measurement, clinical history collection, and assessment of anthropometric and pubertal parameters, with prior DXA data collected when available. The primary aim is to describe BMD values measured by REMS in pediatric osteoporosis, with secondary aims including subgroup analyses and comparison with DXA. A sample of 100 patients is planned. Statistical analyses will assess BMD distributions, correlations with clinical variables, and agreement between REMS and DXA using correlation coefficients and Bland-Altman analysis.",[161,162,163,164,165,27,166,167,168],"Osteogenesis Imperfecta","Osteoporosis","Hypogonadisms","Neoplasia","Obesity & Overweight","Hypercortisolism","Growth Hormone Deficiency (GHD)","Osteopenia","2026-02-13",{"date":171,"type":43},"2026-02-17",{"date":173,"type":43},"2025-12-04",{"date":175,"type":21},"2026-12-31",{"name":177,"class":49},"Meyer Children's Hospital IRCCS",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":185,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":187,"conditions":188,"keywords":4,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":198,"locationsCount":98},"100612695","malnutrition-screening-study-100612695","NCT07256925","Malnutrition Screening Study","LEVEL-UP Turkish Adult Outpatient Screening Study","Inclusion Criteria:\n\n* Participant has voluntarily signed and dated an informed consent form (ICF), approved by an Independent Ethics Committee (IEC)\u002FInstitutional Review Board (IRB), and provided other applicable privacy regulation authorization (if applicable) prior to any participation in the study.\n* Participant is ≥ 18 years of age who attend hospital clinics (medical and radiation oncology, neurology, and geriatrics clinics) as an outpatient for any reason.\n\nExclusion Criteria:\n\n* NA",{"count":186,"type":21},7500,"This is a non-interventional, cross-sectional, non-randomized, observational study to screen for the risk of malnutrition and sarcopenia in outpatients aged 18 and over who attend hospital clinics for any reason in Turkey.",[189,190],"Malnutrition, Calorie","Sarcopenia","2026-01-28",{"date":193,"type":43},"2026-01-29",{"date":195,"type":43},"2026-01-12",{"date":197,"type":21},"2026-07",{"name":96,"class":97},{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":205,"eligibilityCriteria":206,"healthyVolunteers":207,"sex":208,"minAge":18,"maxAge":4,"enrollmentInfo":209,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":211,"conditions":212,"keywords":225,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":98},"100607934","early-life-malnutrition-environmental-enteric-dysfunction-and-microbiome-trajectories-100607934","NCT07195006","Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories","Early Life Diarrhoea Episode(s), Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories From Birth Until 3 Years of Life ; The University of Zimbabwe Birth Cohort Study-2 (UZBCS-2)","UZBCS-2","Inclusion Criteria for Cases:\n\n* MUAC ≤23 cm in pregnancy\n* ≥18 years' old\n* At least 20 weeks' gestational age\n* Height ≥150 cm\n* Planning to be staying in the study area for the next 3 years\n* Willing to participate and comply with all study requirements and procedures.\n\nAny pregnant woman meeting the above eligible criteria regardless of HIV status who meet the above inclusion criteria will be invited to participate in the study\n\nInclusion criteria for Controls\n\n* Age, HIV status, gestational age at enrolment, and area residence matched normo-nourished peers with MUAC ≥25 - ≤35 cm\n* Haemoglobin level of ≥11g\u002FdL\n* ≥18 years' old\n* At least 20 weeks' gestational age\n* Height ≥150 cm\n* Planning to stay in the study area for the next 3 years\n\nExclusion Criteria\n\n* Acute or chronic conditions in mothers interfering with the study according to the judgment of the investigator (HIV infection is not an exclusion criterion)\n* Presence of severe mental health disorders interfering with study procedures according to the judgment of the investigator.",true,"FEMALE",{"count":210,"type":21},368,"Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it. The interaction of the mother with the infant shapes the seeding and the trajectory of the infant intestinal microbiota which is crucial for development of a healthy immune system Malnutrition has been associated with intestinal inflammation, intestinal leakage and reduced calorie absorption. Early life malnutrition and environmental enteric dysfunction (EED) immunopathology remains poorly described in the context of mother-infant dyads. This is essential as malnutrition, poor water, sanitation and hygiene (WASH), including the presence of infectious diseases limit the developmental potential of the exposed infants in SSA, including Zimbabwe. In addition, maternal stress and poor mental health may also affect standard hygiene practices, including how a mother cares for her baby, potentially aggravating EED and the risk of the infant being malnourished.\n\nPrimary outcomes\n\n1. Infant malnutrition and recovery.\n2. Gut dysfunction (gut inflammation, leaky gut, malabsorption, dysbiosis)\n3. Diarrhea episodes, defined as any episode of acute diarrhoea (≥3 passages of loose stool within 24 hours as reported by the mother) occurring before the next study visit.\n\nDefinition of malnutrition outcomes to be assessed in babies born to malnourished women, is a mid- upper arm circumference (MUAC) \\\u003C23cm;\n\n* MUAC for age: Malnourished defined as those below -2 standard (SD) of the World Health Organisation (WHO) reference\n* Weight-for-age: Underweight defined as those below -2SD WHO reference\n* Weight-for-height: Wasted defined as those below -2SD WHO reference\n* Height-for-age: Stunted defined as those below -2SD WHO reference\n* Z-scores (as they are i.e. a continuous variable, taking age of infants into account)\n* A composite variable, any of malnourished, underweight, wasted or stunted.",[213,214,27,215,216,217,218,219,220,221,222,223,224],"Malnutrition Pregnancy","Malnutrition in Children","Environmental Enteric Dysfunction","Gut Dysbiosis","Gut Permeability, Gut Inflammation","Diarrhea Infectious","Maternal Stress","Child Mental Health","Natural Killer Cell Mediated Immunity","Mycotoxin Biomonitoring","Environmental Exposures","Cell-Mediated Immune Deficiency",[226,227,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242],"diarrhoeal episodes","short chain fatty acids receptor agonists","intestinal inflammation, leakage and calory extraction","toxins in drinking water and food","macro- and micronutrient composition of breast milk","human anti-Gal antibodies","mitochondria health and nutrient uptake","endothelial dysfunction and oxidative stress","hormonal mediated molecular signalling mechanisms","interaction of epigenetics & socioeconomic factors","microbiota, pathobionts and oral microbiota","metagenomics","undernutrition and intestinal infections","infant mortality, morbidity within 1st 1000 days of life","low mid upper arm circumference","sleep adequacy in maternal mental health","chronic inflammation","2025-09-18",{"date":245,"type":43},"2025-09-26",{"date":247,"type":43},"2025-01-27",{"date":249,"type":21},"2032-12-31",{"name":251,"class":49},"University of Zimbabwe",{"id":253,"slug":254,"hasResults":11,"nctId":255,"briefTitle":256,"officialTitle":257,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":11,"sex":17,"minAge":83,"maxAge":18,"enrollmentInfo":259,"targetDuration":4,"studyType":59,"phases":261,"briefSummary":262,"conditions":263,"keywords":266,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":4},"100603467","nutritional-assessment-in-patient-of-mucopolysaccharide--100603467","NCT07136896","Nutritional Assessment in Patient of Mucopolysaccharide \"","Nutritional Assessment of Patient of Mucopolysaccharide","Inclusion Criteria:Confirmed diagnosis of mucopolysaccharidosis (any subtype) by enzymatic assay or genetic testing\n\nAge between 1 and 18 years\n\nStable clinical condition at time of enrollment\n\nInformed consent obtained from parent\u002Fguardian, and assent from child when applicable -\n\nExclusion Criteria:Presence of other chronic conditions affecting growth or nutrition (e.g., untreated endocrine disorders, severe cardiac failure unrelated to MPS)\n\nAcute illness or hospitalization within the last 2 weeks prior to assessment\n\nPatients who received nutritional supplementation or dietary intervention within 3 months prior to enrollment that could affect baseline nutritional assessment\n\nRefusal or inability to comply with study assessments\n\n\\-",{"count":260,"type":21},40,[61],"\" Nutritional assessment in patients of Mucopolysaccharide \"",[264,27,265],"Mucopolysaccharidosis (MPS)","Undernutrition",[267,268],"Caloric deficiency","Pediatric nutrition","2025-08-15",{"date":271,"type":43},"2025-08-22",{"date":273,"type":21},"2025-08-16",{"date":275,"type":21},"2026-08-30",{"name":277,"class":49},"Assiut University",{"id":279,"slug":280,"hasResults":11,"nctId":281,"briefTitle":282,"officialTitle":283,"acronym":284,"eligibilityCriteria":285,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":286,"targetDuration":4,"studyType":59,"phases":288,"briefSummary":289,"conditions":290,"keywords":292,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":299,"completionDateStruct":301,"leadSponsor":303,"locationsCount":4},"100593717","nutritional-support-with-tgf-2-food-for-special-medical-purposes-tgf-2-fsmp-in-adult-allogeneic-hematopoietic-stem-cell-transplantation-allo-hsct-for-the-prevention-of-malnutrition-a-prospective-randomized-multicenter-study-100593717","NCT07010068","Nutritional Support With TGF-β2 Food for Special Medical Purposes (TGF-β2 FSMP) in Adult Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) for the Prevention of Malnutrition: a Prospective, Randomized, Multicenter Study","Nutritional Support With TGF-β2 Food for Special Medical Purposes (TGF-β2 FSMP) in Adult Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) for the Prevention of Malnutrition: a Prospective, Randomized, Multicenter Study - (TGF-NUTRIALLO Study)","TGF-Nutri","Inclusion Criteria:\n\n* Intact intestinal tract\n* Life expectancy more than 12 weeks\n* Allogeneic stem cell transplantation\n* Signed informed consent\n\nExclusion Criteria:\n\n* Active hematological disease at the beginning of conditioning\n* Personal history of inflammatory bowel diseases\n* Personal history of bowel resection\n* Personal history of gastric bypass procedures\n* Enrolment in a competitive prospective study (malnutrition or GVHD as primary outcome)\n* Subjects with known hypersensitivity to milk proteins or components of Modulen-IBD",{"count":287,"type":21},214,[61],"prospective, randomized, multicenter study to confirm the potential benefits of TGF-β2 enriched FSMP. The primary objective is to evaluate the superiority of supplementing with TGF-β2 FSMP (experimental arm) compared to best supportive treatment (BST) in preventing malnutrition in patients submitted to allo-SCT. The secondary endpoints include the assessment of reduction of incidence of severe acute GVHD at day +100.",[27,291],"Stem Cell Transplant Complications",[293,294,295],"Stem Cell Transplant","malnutrution","gvhd","2025-06-04",{"date":298,"type":43},"2025-06-08",{"date":300,"type":21},"2025-06-01",{"date":302,"type":21},"2028-06",{"name":304,"class":49},"Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia",{"id":306,"slug":307,"hasResults":11,"nctId":308,"briefTitle":309,"officialTitle":310,"acronym":311,"eligibilityCriteria":312,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":313,"enrollmentInfo":314,"targetDuration":4,"studyType":59,"phases":315,"briefSummary":316,"conditions":317,"keywords":322,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":333,"lastUpdatePostDateStruct":334,"startDateStruct":336,"completionDateStruct":338,"leadSponsor":340,"locationsCount":98},"100590008","brief-title-the-role-of-nutrition-in-the-rehabilitation-of-patients-with-eating-disorders-after-a-vascular-stroke-100590008","NCT06961825","Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke.","The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke: A Randomized Controlled Trial Investigating the Effect of Protein Supplementation on Functional Recovery, Sarcopenia, Osteopenia, and Nutritional Status in Stroke Patients With Hypoalbuminemia.","Nutristroke","Inclusion Criteria:\n\n* Age range: Adults aged 18 to 85 years\n* Diagnosis: Patients diagnosed with a stroke (cerebrovascular accident) within the last 4 to 6 weeks\n* Serum albumin levels: Patients with low serum albumin levels (\\\u003C 3.5 g \u002F dL)\n* Nutritional intervention requirement: Patients who require nutritional intervention to support rehabilitation and nutrition\n* Informed consent: Patients who have completed the consent form for participation in the study and acceptance of the intervention\n\nExclusion Criteria:\n\n* Severe infections or serious cardiopulmonary conditions: Patients with severe infections or serious cardiopulmonary conditions requiring immediate medical intervention, which may affect nutrition and rehabilitation\n* Comorbidities: Patients with comorbid conditions such as renal or liver disease\n* History of stroke or neurological conditions: Patients with a history of stroke or other neurological conditions who do not meet the criteria for rehabilitation\n* Severe mental or psychological conditions: Patients with severe mental or psychological conditions who are unable to understand or consent to participation in the study","85 Years",{"count":157,"type":21},[61],"Brief Summary: The main objective of this thesis is to investigate the role of nutrition - specifically the administration of protein supplements (single dose and double dose) - in the rehabilitation of stroke patients with low albumin levels in relation to sarcopenia, osteopenia and functional recovery indices. The study will follow a randomized controlled trial design, incorporating clinical observation, analysis of biochemical markers, and assessment of physical and functional parameters. Participants will be randomly assigned to one of the three groups: (1) Group 1, receiving no protein supplementation (control group), (2) Group 2, receiving a single dose of protein supplement and (3) Group 3, receiving a double dose of protein supplement. The intervention will last for at least six weeks or until the biochemical markers of albumin normalize and the patient resumes regular oral intake. Biochemical assessment with be conducted through regular nutritional evaluations including measurement of serum albumin, prealbumin, C - reactive protein, creatinine, blood glucose and glycosylated hemoglobin (HbA1c), urea, electrolytes, urine albumin and additional inflammatory markers. Bone density will be assessed using DEXA, MBSR and hip measurements to determine the potential improvements resulting from the intervention. Muscle mass will be evaluated using whole - body DEXA analysis, while muscle strength and mobility will be assessed through grip strength tests and fine gait assessments. Functional recovery will be evaluated usings standardized tools for activities of daily living (Barthel Index), mental state (Geriatric Depression Scale) and quality of life (SF - 36), as well as mobility and walking tests such as the Timed Up and Go Test and 6 - Minute Walk Test. The collected data will be analyzed using appropriate statistical tools, including comparison models (ANOVA, Mann - Whitney U test) and correlation models (Pearson - Spearman). This research is expected to enhance theoretical knowledge regarding the relationship between nutrition, biochemical markers and rehabilitation outcomes in stroke patients with hypoalbuminemia. More specifically, it aims to explore the underlying mechanisms through which nutrition affects recovery - a field that remains unexplored. Additionally, the anticipated finding may contribute to the development of clinical guidelines and therapeutic approaches for the nutritional management of patients with low albumin levels, promoting personalized nutritional strategies that support effective post - stroke rehabilitation.",[318,319,190,168,27,320,321],"Stroke","Hypoalbuminemia","Protein-energy Malnutrition","Functional Decline",[323,324,325,326,327,328,329,330,331,332],"protein supplementation","nutritional intervention","albumin levels","stroke","stroke rehabilitation","eating disorders","malnutrition","nutritional assessment","sarcopenia","osteopenia","2025-04-29",{"date":335,"type":43},"2025-05-08",{"date":337,"type":21},"2025-05-05",{"date":339,"type":21},"2030-05-05",{"name":341,"class":49},"University of Ioannina",{"id":343,"slug":344,"hasResults":11,"nctId":345,"briefTitle":346,"officialTitle":347,"acronym":4,"eligibilityCriteria":348,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":349,"enrollmentInfo":350,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":351,"conditions":352,"keywords":355,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":359,"lastUpdatePostDateStruct":360,"startDateStruct":362,"completionDateStruct":364,"leadSponsor":366,"locationsCount":98},"100550875","relative-energy-deficiency-in-rowers-100550875","NCT06452758","Relative Energy Deficiency in Rowers","Relative Energy Deficiency in Females and Males Rowers - Observational Study","Inclusion Criteria:\n\n* Membership in Polish Rowing Team,\n* minimum five years of training,\n* total training time minimum of 240 minutes,\n* filling out a food diary,\n* finishing 2000-meter ergometer test.\n\nExclusion Criteria:\n\n* Probiotics within the last three months,\n* prebiotics within the last three months\n* antibiotic therapy within the last three months,\n* dietary regime,\n* gastrointestinal diseases.","23 Years",{"count":20,"type":21},"This study aims to learn about relative energy deficiency in male and female rowers at the end of the direct sport preparation phase of the annual training cycle. The main questions:\n\n\\- How will energy intake influence leptin, cortisol levels, mood, gut discomfort, and permeability? The observational study involves male and female rowers from the Polish rowing team.\n\nParticipants will perform 2000 meter ergometer test and 6000 ergometer test in annual training cycle. Researchers will compare outcomes from both tests.",[353,354,189],"Endothelial Dysfunction","Mood Disorders",[356,357,358],"relative energy deficiency","gut permeability","rowers","2024-06-11",{"date":361,"type":43},"2024-06-13",{"date":363,"type":21},"2024-06-20",{"date":365,"type":21},"2024-06-30",{"name":367,"class":49},"Poznan University of Physical Education"]