[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malnutrition-infant\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malnutrition-infant":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100484615","efficacy-of-mobile-health-application-in-promotion-of-exclusive-breast-feeding-and-young-child-feeding-practices-in-pakistan-100484615",false,"NCT05590351","Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan","Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Pregnant women in the third trimester at 36 +\u002F- 1 week of gestation.\n2. Planned to stay in their respective areas for at least 1 year after delivery\n3. Planned to get the infant immunized from the respective FHC of the hospitals.\n4. Have access to smart phones with internet connection.\n5. Registered and planning to deliver to any of the Secondary Care Hospitals\n6. Can read and write in local language (English and\u002For Urdu).\n7. Consent to participate and remain in the study until 1 year of child age\n\nExclusion Criteria:\n\n1. High-risk including maternal neurological\u002Fheart\u002F autoimmune\u002Frenal disease, preeclampsia, placenta previa, multiple gestations (twins\u002Ftriplets), fetal structural\u002Fgenetic anomalies, fetal growth restrictions, and birth trauma\u002Frequiring NICU admission.\n2. Women who plan to move to different location after delivery",true,"FEMALE","18 Years","48 Years",{"count":21,"type":22},300,"ESTIMATED","INTERVENTIONAL",[25],"NA","Early life nutrition is the key modifiable determinant of child growth, development, survival and diseases of adult onset. Pakistan ranks highest for neonatal mortality rate (44.2\u002F1000 live births (LBs)) globally. One third of under-five deaths (74.9\u002F1000 LBs) are attributable to high prevalence of stunting (38%), underweight (23%) and wasting (7%), greatly related to feeding practices. Given the low prevalence of exclusively breast fed (EBF) (48%) and use of minimum acceptable diet (13%), mitigation of early life nutritional risk through promotion of EBF and Young Child Feeding Practices (YCFP) provides a critical window of opportunity for intervention. Secondary Care Hospitals (SCH) of the Aga Khan Health Services Pakistan provide essential maternal and child health services for low-middle income population. Babies born at these SCHs are followed up for vaccination, growth-monitoring and other services at the closely affiliated Family Health Centers (FHCs) run by Lady Health Visitors (LHVs). We aim to examine the effectiveness of a locally designed m-Health application for empowering mothers for child nutritional care as a potentially sustainable approach. The first six months of formative research would identify perceptions, barriers and facilitators for EBF and YCFP using self-determination behavioral theory, among multi-parous pregnant mothers enrolled at three SCHs of Karachi. A randomization trial would be conducted during next 18 months among near-term pregnant women who have access to smart-phones. A culturally appropriate mhealth application called first diet would be developed to provide personalized push messages delivered weekly by the LHVs. Non-intervention group will receive face-face nutritional counselling by the research staff at FHC following routine vaccination and growth-monitoring schedule. Mothers would followed-up from one month prior to expected delivery to child's first birthday. We expect 20% improvement in rates of EBF and YCFP with m-Health intervention. If proven effective, m-health would be incorporated in routine child care provision by LHVs.",[28,29],"Malnutrition, Infant","Malnutrition, Child",[31,32,33],"infant & young child feeding practices","stunting","wasting","RECRUITING","2026-02-10",{"date":37,"type":38},"2026-02-12","ACTUAL",{"date":40,"type":38},"2026-02-02",{"date":42,"type":22},"2027-12",{"name":44,"class":45},"Aga Khan University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":16,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":46},"100562162","mother-screening-for-relapse-using-mid-upper-arm-circumference-among-children-recovered-from-severe-acute-malnutrition-full-scale-trial-100562162","NCT06599580","Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (Full Scale Trial)","Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (MAMAN)","MAMAN","Inclusion Criteria:\n\n* Caregiver's aged 18 years old or older or a legal guardian or a relative aged 18 or older\n* Child aged 6-54 months\n* Child has recovered from an episode of severe acute malnutrition per Burkinabè national guidelines (weight-for-height ≥ -2 and\u002For mid-upper arm circumference ≥ 12.5 cm in the past month, with the criterion used for admissions corresponding to the original admission criteria)\n* Family is planning to stay in the study area for 6 months\n* Appropriate consent from the caregiver or guardian.\n\nExclusion Criteria:\n\n* Caregiver age under 18 years old, or legal guardian or relatives under 18 years old\n* Child age \\\u003C 6 months or \\> 54 months\n* Twins\u002Fmultiple births\n* Children with feeding issues\n* Did not recover from severe acute malnutrition in the past month\n* Family is planning to move out of the study area in the next 6 months\n* Caregiver or guardian refuses to provide consent","ALL","6 Months","54 Months",{"count":59,"type":22},2400,[25],"A 1:1:1 individually randomized unmasked controlled trial is proposed in which caregivers will be trained to screen their children who have recovered from an episode of SAM (severe acute malnutrition) using MUAC (mid-upper arm circumference) tapes. One arm will include caregiver screening with a mid-upper arm circumference tape and usual monthly follow-up schedule for the first 3 months post enrollment and a final follow-up at 6 months. Another arm will include caregiver screening with a mid-upper arm circumference tape and a reduced follow-up schedule for one visit at 3 months and a final visit at 6 months. The third arm will adhere to the current standard of care, which is no caregiver training to conduct mid-upper arm circumference screenings and monthly clinic-based follow-up appointments for 3 months with a final visit at 6 months post enrollment. Children aged 6-54 months with a documented recovery from uncomplicated severe acute malnutrition that was managed in a participating outpatient nutritional program and their caregivers will be eligible for inclusion in the trial. Caregivers will be trained to screen their children weekly for 6 months following discharge from the nutritional program and will be counseled to bring their child back to the nutritional program should their mid-upper arm circumference value fall in the red zone of the mid-upper arm circumference tape (\\\u003C 11.5 cm). All children will be seen at 3 and 6 months for the primary outcome assessment. By conducting this study, our primary goal is to determine if training caregivers to screen their children for relapse to MAM (moderate acute malnutrition) or SAM (severe acute malnutrition) using mid-upper arm circumference tapes following recovery from SAM (severe acute malnutrition) will reduce the risk of relapse. An additional aim is to assess the level of acceptability of caregivers screening children for malnutrition using mid-upper arm circumference tapes from both a clinic and caregiver perspective.",[29,28,63,64,65],"Malnutrition or Risk of Malnutrition","Hemoglobin Level Measurement","Anemia",[67,68,69,70],"MUAC (mid-upper arm circumference)","Caregiver screening","malnutrition","home based malnutrition screening","2025-11-17",{"date":73,"type":38},"2025-11-20",{"date":75,"type":38},"2025-03-20",{"date":77,"type":22},"2027-11",{"name":79,"class":45},"University of California, San Francisco",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":55,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100544709","providing-breastfeeding-support-after-discharge-from-hospital-to-improve-growth-and-development-of-malnourished-infants-100544709","NCT06372418","Providing Breastfeeding Support After Discharge From Hospital to Improve Growth and Development of Malnourished Infants","Enhancing Growth and Development Among Malnourished Infants Recovering From a Serious Illness (IBAMI-2)","IBAMI-2","Inclusion Criteria:\n\nInfants admitted to Kilifi County Hospital (KCH) aged between 4 weeks and 12 weeks old\n\nAND Wasting or underweight assessed by Weight-for-length Z-score (WFLz)\\\u003C-2 OR Weight-for-age Z-score (WFAz) \\\u003C-2\n\nOR Mid upper arm circumference (MUAC)\\\u003C110mm OR presence of bilateral pitting oedema AND\n\n* Any possibility to breastfeed (carer of reproductive age willing to breastfeed and infant without clinical abnormalities obstructing breastfeeding\n* Caregivers consent to participation in the study\n\nExclusion Criteria:\n\nInfants with no possibility to breastfeed. OR Infants with congenital abnormalities that would affect breastfeeding e.g. cleft palate or invalidate the use of normal growth standards.\n\n\\-","4 Weeks","12 Weeks",{"count":91,"type":22},250,[25],"The current guidelines used to manage malnutrition among infants aged below 6 months (u6m) recommend that infants admitted to hospital with malnutrition be supported to reestablish exclusive breastfeeding before discharge. Studies have shown that reestablishing exclusive breastfeeding among infants being treated for acute malnutrition is possible. However, follow-up of the infants after discharge has revealed poor growth raising questions about what happens to infant feeding practices after discharge and whether providing breastfeeding support to mothers after discharge would help improve the recovery and growth of their infants.\n\nProviding a package of home-based care with breastfeeding support to mothers of infants u6m recovering from acute malnutrition has the potential to improve the retention of exclusive breastfeeding and lead to enhanced infant growth and survival. To date, no such post-discharge package of care is available in Kenya or other lower and meddle income countries (LMICs). The aim of this study is to apply participatory, qualitative and quantitative approaches to develop and evaluate the impact of a post-discharge package of care on the growth and development of acutely ill malnourished infants after discharge from hospital.",[28,95],"Breastfeeding, Exclusive","NOT_YET_RECRUITING","2024-04-17",{"date":99,"type":38},"2024-04-18",{"date":101,"type":22},"2024-05",{"date":103,"type":22},"2027-02",{"name":105,"class":45},"University of Oxford"]